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Author Topic: Anyone use L-Carnitine? Does it work? Does it help?  (Read 31358 times)
Andy
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« Reply #30 on: December 11, 2017, 10:14:31 PM »

I can't find the source I mentioned, but this explains the suspected correlation between uric acid levels and low carnitine levels.
http://journals.plos.org/plosgenetics/article?id=10.1371/journal.pgen.1000504
Quote
In spontaneously hypertensive rats, L-carnitine decreases serum UA levels and the age-dependent rise in serum UA [31],[32]. Kidneys absorb 95% of carnitine from the glomerular filtrate via an active Na+-dependent transport mechanism [33]. Impairment of this reabsorptive function can lead to carnitine deficiency, in which hyperuricemia may be present because carnitine competes for renal tubular excretion

Interestingly, at least two patents have been applied for for potential treatments for gout, based on L-carnitine.
https://www.google.ch/patents/US20080249168
https://www.google.com/patents/EP2147671A1?cl=en
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Andy

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