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A message for all  parents who are thals. Keeping your iron load under control is an absolute obligation to your children.
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Author Topic: Cultured Red Blood Cells:Life Span in Vivo  (Read 4239 times)
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Little A

« on: June 09, 2011, 12:25:00 PM »


I found this study in the list of clinical trials that your have listed on the facebook thalpal site.  This seems really interesting!

Brief Summary

Official Title: “First Pilot Study Evaluating the Life Span of Autologous Cultured Red Blood Cells (cRBC) Generated From Peripheral Stem Cells in Three Healthy Volunteers - Feasibility Study”

To study the in vivo life span in healthy volunteers of red blood cells generated in vitro from autologous peripheral stem cells. The study will be carried out in 4 phases : - production in vitro of the equivalent of 1 ml of blood, i.e. 5x10e9 enucleated RBC from mononuclear cells isolated from an HSC graft obtained from a healthy volunteers donor. - labeling of these cRBC with 51 Cr - reinjection of the autologous cRBC - follow up of the receivers for a maximum 33 days to measure the half-life span of the injected cells.

Study Type: Interventional
Study Design: Endpoint Classification: Bio-availability Study, Intervention Model: Single Group Assignment, Masking: Open Label, Primary Purpose: Health Services Research
Study Primary Completion Date: November 2011



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