It sounds very much like you have extramedullary hematopoiesis (EH) taking place in your liver, and this is also a reason why spleens are sometimes removed. The EH is the body's attempt to grow red blood cells outside the bone marrow and this can take place anywhere in the body, most often in the abdominal cavity, but it can take place anywhere, even within cells. This is much more common in intermedia thals who do not transfuse, but it is also found in majors who are under-transfused and occasionally it occurs in thal minors. I know one minor who has a growth of red blood cells that measured 18 cm and pressed so hard on her lungs that it caused an asthma-like condition because her lungs could not expand fully. Doctors may not hear much about this, but in my role here, I have heard reports from thal minors who do have EH and from those whose spleens became so enlarged that they needed it removed, so it is a problem for some thal minors, and probably far more than is known because most cases go un-diagnosed. In majors, this is treated by raising the Hb with transfusion and sometimes the drug, hydroxyurea is used to try to reduce the amount of blood being produced outside the bone marrow. My only advice is to do everything you can to keep your Hb level up. Wheatgrass and resveratrol should be tried for at least one year to see if your Hb will rise. Folic acid should be taken daily. Talk to your doctors about EH. They may not be aware that it does sometimes occur in minors, but that is exactly what happens. Red blood cells grow outside the bone marrow, and in your case it's in your liver. The main danger from these masses are when they cause great pressure on the spine or organs, but this is usually with masses growing in the abdomen.