I v desferal taken how long

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Offline jatin

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I v desferal taken how long
« on: July 05, 2016, 02:32:27 PM »
Hi all I have query pls reply and share experiences.
One of my know thal major patient ferrtin is around 6500 from last 2 yrs.
T2 * mri of heart is 11.0 ms
T2 * mri of liver is severe around 1
T2* mri of pancreas is 3.3 severe.
Patients is on deferasirox 500 mg 4 tabs.
Weight is 40 kg ..
He has taken inj.desferal  for sat sun by pump for around 6 months .
Pls suggest what is max numbers of days I'v desferal can be given .thanks

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Offline Andy Battaglia

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Re: I v desferal taken how long
« Reply #1 on: July 09, 2016, 02:12:51 AM »
IV desferal is usually given for no more than two weeks at a time, unless the patient is in heart failure. In between IV sessions, pumping should continue at least 5 times per week. The patient's dose of deferasirox is too low. With those iron numbers, the patient should be on high dose of at least 40 mg/kg daily. For this patient, it should be 1600-2000 mg daily, split into two doses to maximize the benefit. It is critical that aggressive chelation be undertaken for at least two years.
Andy

All we are saying is give thals a chance.

 

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