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Thalassemia Patients and Friends and thalpal Ā© A. Battaglia 2019





55156 Posts in 5879 Topics by 6155 Members
Latest Member: jchang121

A message for all  parents who are thals. Keeping your iron load under control is an absolute obligation to your children.
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Author Topic: Sibling match percentage - Poll  (Read 3043 times)
Sunny2701
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« on: April 11, 2018, 05:25:37 PM »

Poll to get the real life figure for sibling match from the people on this website. We have been hearing 20%, 25%. Let see how much we get
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Sunny2701
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« Reply #1 on: September 30, 2018, 03:39:22 PM »

Common folks i have around 400 reads on this poll and only 2 responses. This poll is not only for me, its for everyone trying to find answers on thalpal
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JohnnyBoy53
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« Reply #2 on: July 19, 2019, 09:00:02 PM »

Isn't it 1/4? I remember seeing a graphic about this at a conference of the chances a sibling will be a match. That number also matches with your current numbers (20% - 25%)
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Andy Battaglia
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Will thal rule you or will you rule thal?


« Reply #3 on: July 27, 2019, 02:28:32 PM »

For two beta thal carriers, yes there is a 25% chance that a child would be a major. Real life experience can vary greatly, as life does not give a damn about the odds, hence families with 3 children who are all thal major.
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Andy

All we are saying is give thals a chance.
zahra
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« Reply #4 on: November 06, 2019, 10:38:35 PM »

Maybe I am wrong but I feel like this question isnt about chances of having thal kids being thal minor parents but about chances of finding a sibling that matches for bone marrow transplant.
Initially we were recommended PGD  with  IVF but the expert said the chances of a healthy ( non thal) child are good but matching sibling is chance. You could have 20 siblings and none of them match or one only and they match.
That said with the new haplo transplants you only need a 50% match. All parents and children are 50% matches. Siblings may have a higher percentage of matching. Amazingly haplo transplants have less GVHD too. My son had a 50% haplo BMT from his brother 3 years ago and is doing well with no GVHD. I look forward to when haplo transplants are available everywhere bc nearly everyone will have a match then.
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