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Thalassemia Patients and Friends and thalpal Ā© A. Battaglia 2018

54982 Posts in 5842 Topics by 6089 Members
Latest Member: Ange!123

We love you, Lisa.
May you Rest in Peace,
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Author Topic: transfusion reactions - delayed  (Read 1121 times)
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« on: August 04, 2018, 01:47:09 PM »

Hi All,
51 y/o Thal Intermedia here who is starting chronic transfusion therapy since I can no longer maintain a decent Hgb and have severe pulmonary hypertention.  My question is After 2 units (was going to do three over two days) I develop high fevers 102.F and severe body aches.  I premedicate with tylenol and benadryl but within a few hours after the end of the transfusion I am completely debilitated.  Does this ever get better?  Anything else to do?  Doc told me it wasn't going to be easy, but I don't know if I can do this every 3-4 weeks...
Thanks for any insight...  Yes I know I have a lot of anitbodies!!!
Andy Battaglia
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« Reply #1 on: August 04, 2018, 07:51:10 PM »

I would suggest transfusing no more than two units at a time and also trying a slower rate for the transfusion to see if you react less. If that doesn't help, can you get transfused only one unit and see if that reduces the reaction? I'm wondering if the problem is the volume of blood that is being taken at once. I am assuming the blood is properly matched.


All we are saying is give thals a chance.
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« Reply #2 on: August 05, 2018, 04:08:33 PM »

the blood is properly matched.  I  am A+ and receive either A+ or O+  I receive each unit over 3 hours and never have a reaction during the transfusion itself.  It's just frustrating because I feel as though it is a waste of time as I am not receiving any benefit from the RBCs. 
Thanks again
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