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Thalassemia Patients and Friends and thalpal © A. Battaglia 2019

55105 Posts in 5866 Topics by 6148 Members
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A message for all  parents who are thals. Keeping your iron load under control is an absolute obligation to your children.
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Author Topic: Spirulina Therapy  (Read 1291 times)
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« on: December 13, 2018, 01:37:44 PM »

J Pediatr Hematol Oncol. 2018 Dec 7. doi: 10.1097/MPH.0000000000001380. [Epub ahead of print]
Cardioprotective Effects of Spirulina Therapy in Children With Beta-Thalassemia Major.
El-Shanshory M1, Tolba O, El-Shafiey R, Mawlana W, Ibrahim M, El-Gamasy M.
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Cardiac failure in children with Thalassemia major (TM) is the major cause of death due to iron overload. Spirulina is a micro alga with proven anti-inflammatory, antioxidant and may have a cardioprotective effect.

The aim of this study was to evaluate the possible beneficial effect of spirulina supplement in TM children.

It is an interventional study carried out in 60 children with TM and 30 healthy children matched for age and sex as control. Both groups received spirulina supplement at a dose of 250 mg/kg/d for 3 months. 2D Echo, Tissue Doppler, and speckle tracking imaging (STI) were done for all the studied cohort before and after the 3-month duration of spirulina supplement.

There was significant improvement in hemoglobin level at the end of 3-month period (8.27±1.3 vs. 9.023±1.7; P <0.033) with decrease the frequency of blood transfusion in TM patients (66.6% vs. 40% required transfusion at interval less than 2 wk). Left ventricle global longitudinal strain (LVGLS) significantly improved after 3-month period (-21.7±4.64 vs. -24.67±4.478; P <0.002).

Spirulina supplement has possible beneficial effect in minimizing the frequency of blood transfusion as well as cardioprotective effect against cardiac damage in TM patients.

PMID: 30531602 DOI: 10.1097/MPH.0000000000001380

Andy Battaglia
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« Reply #1 on: December 15, 2018, 02:00:18 PM »

Very helpful information. I was just asked about spirulina last week.


All we are saying is give thals a chance.
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In Darkest Day in Brightest Night...

« Reply #2 on: December 19, 2018, 05:26:18 AM »

This is very interesting. But the dose is above average RDA.
In my case it would require 16,5 gr. I don't know...
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