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Author Topic: Help Me Understand Blood Test  (Read 542 times)
Hurricane3
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« on: March 03, 2020, 01:16:42 PM »

Hey,

I've known I had thalassemia for a while now but never thought about it too much.

RBC - 6.94
HGB - 15.2
HCT - 49
MCV - 70.6
MCH - 21.9
MCHC - 31.0
RDW 16.4
Ferritin - 491
Iron % Sat - 49

I have a few questions.

1) Based on these results, would you say I should experience any symptoms? I play table tennis and I seem to tire out a bit more easily than my peers.

2) Would you consider this a bad Ferritin level? My levels have been this way for the past couple of years, so not due to inflammation, and I've had symptoms of high ferritin, such as low libido.
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Andy Battaglia
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« Reply #1 on: March 22, 2020, 05:13:58 PM »

1) Even with your high Hb, you may have some symptoms that are not related to Hb, but instead are related to the overproduction of red blood cells. Your RBCis quite high, which does show that your normal Hb is accomplished by overproduction of red blood cells. The unmatched globin chains caused by alpha and beta globin not being evenly produced, and along with the by products of the destruction of defective red blood cells can cause many issues in thalassemics. In fact, the main goal of transfusion in majors is not necessarily raising the Hb. The goal, which can only be accomplished by raising the Hb is to slow down the ineffective electrophoresis that takes place in the bone marrow and produces so many defective red cells. This also takes place in minors, so even though you have a good Hb level, it takes a high RBC to make that happen.
Many of the nutritional recommendations I give are intended to help the body produce better quality red cells, that aren't removed by the body so quickly.

2) The ferritin is high, but unless you have a history of long term iron supplementation, it should have no real relevance.

Has your bilirubin level been tested? I would assume it is high, due to red blood cell destruction, which produces bilirubin.
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Andy

All we are saying is give thals a chance.
Giovanni Clarke
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« Reply #2 on: July 06, 2020, 07:01:09 PM »

Hi Andy,

Could you review my most recent CBC, as my doctors haven't explained what it means?

MCHC.            28.7L      31.5-35.7 g/dL
PLT count.       279        150-379 10^3/uL
RDW.              14.8       12.3-15.4%
Hemoglobin.    13.3       11.1-15.9 g/dL
MCH.              21.6L      26.6-33.0 pg
RBC count.      6.15H     3.77-5.28 10^6/uL
Hematocrit.     46.4       34.0-46.6%
MCV.               75L        80-100fL
WBC count.      5.3        3.4-10.8 10^3/uL

Thanks!
Giovanni
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