Discussion Forums > Working Towards a Cure
Resveratrol Research Update
Andy Battaglia:
We've talked about resveratrol and its role as a possible fetal hemoglobin inducer. With this report released in December, 2007 we can remove the word possible and replace it with confirmed.
From http://ecam.oxfordjournals.org/cgi/content/full/nem139v1
--- Quote ---In our laboratory, when erythroid precursor cells from normal subjects were treated with increasing concentrations of resveratrol and analysis of accumulation of globin mRNA sequences was performed by quantitative RT-PCR, a clear increase in accumulation of {gamma}-globin mRNA content was found (lower part of Fig. 3). Increase in accumulation of {alpha}-globin and β-globin mRNA was much lower. Taken together these data strongly indicate resveratrol as a strong inducer of HbF and a selective stimulator of the expression in {gamma}-globin genes.
--- End quote ---
Resveratrol is a red grape extract and should be strongly considered as a complimentary medicine for increasing fetal hemoglobin levels. These natural methods can be combined to achieve a better effect. Non-transfusing intermedias and minors with Hb issues should especially take note of this but I think most thals can benefit. This whole article provides some fascinating insight into methods nature has provided for raising hemoglobin levels. I believe that through the course of history, that those living in areas of the world where thalassemia is prominent, must have had some natural methods to help deal with it. Science is now rediscovering some of these methods.
kabir_love:
i had already started giving to my son
i bought from this site and this product
http://www.gonsi.com/products/product-detail.cfm/sku-835003003068
Andy Battaglia:
I was posting to ask you to try this when you posted and said you have bought this product. This latest report confirms its effect.
Best wishes.
Zaini:
Hi Andy,
Can we use resveratrol,wheatgrass and IP6 at the same time?
ZAINI.
Andy Battaglia:
Yes. The only caution for resveratrol is among women who have breast cancer because of its estrogen like properties. This is the same warning given about soy products in women with breast cancer, and even with that warning, soy can be used in moderation by women with breast cancer.
The effects of supplements are cumulative and what I am seeing is that the mechanisms that give them their positive properties are different for each supplement, resulting in different approaches to the problems.
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