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The Carao Trial - How effective is it & who benefits most etc.

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Sharmin:
Dear Lloyd,

I will have some results by Monday.  Soon after starting Carao my son had the noravirus so there was some interruption in taking carao other than that he has been taking it. 

1. Confirmation of delivery of the carao  -  October 23, 2008
2. Date when carao is begun - October 23, 2008
3. Dose given - 4 tsp with warm milk
4. Age and diagnosis of patient - 10 years, thalassemia major
5. Average hb before carao was begun (the last several blood test results, if available) - pretransfusion hg 90 - 100
6. Results of all hb tests done during or soon after the period of use of carao.
    Blood test results from November 24th
    Hemoglobin   101      110 – 157 g/L
    Hematocrit    0.28      0.34 – 0.46 L/L
    RBC      3.2               3.8 – 5.6 10E12/L
    MCV      87                75 – 91 fL
    MCHC      360
    RDW      16.7             11 – 16 %
    Platelet Count   355     
    WBC      5.9
    Neutrophils   2.8
    Lymphocytes   2.1
    Monocytes   0.5
    Eosinophils   0.0
7. Whether or not any other treatments were started during the period that carao was given - began B complex (50mg) October   
    25th.     
8. Any extra observations, such as observations on energy level and effects on the overall health of the patient - increased energy     
    level and positive mood change. 

My son has gone through some treatment this year that may also influence his results, however I will continue to post my observations and his lab results. 

Sharmin

maha:
Hi Lloyd
Sorry for the delay. I had no access to the net for the past three months. I am back now but probably lost too. I did post yesterday but that was probably not the relevant thread.
My son has been on carao for more than a year now. There has been no positive change on his hb. The last two months I was able to give him only half the daily dose as he had so many other meds and was forever throwing tantrums. Now I am back to giving him 2 tsp.
thankyou
maha

Sharmin:
Lloyd,

My son had a blood test this morning.  His hg after 3 weeks is 91, a little lower than we had hoped to see it and we are hoping to see it improve for next time. He will be transfused tomorrow.   I will get the details of his blood test once I have them.

Sharmin

Sharmin:
1. Confirmation of delivery of the carao  -  October 23, 2008
2. Date when carao is begun - October 23, 2008
3. Dose given - 4 tsp with warm milk
4. Age and diagnosis of patient - 10 years and 4 months, thalassemia major
5. Average hb before carao was begun (the last several blood test results, if available) - pretransfusion hg 90 - 100
6. Results of all hb tests done during or soon after the period of use of carao.
    Blood test results from January 5th, 2009
    hemoglobin 98

7. Whether or not any other treatments were started during the period that carao was given - began B complex (50mg) October   
    25th.     
8. Any extra observations, such as observations on energy level and effects on the overall health of the patient - his energy has been great during the last 3 weeks - but for a cold he got on Saturday.  He also has some fever and headache. 
   
Sharmin

Lloyd Standish:
Sharmin and Zaini,
Thanks very much for the feedback.  It is probably too early to come to conclusions, and too few case histories, but I think the results posted tend to support the theory I posted earlier: benefits for thal major from carao will be primarily improved energy level, with little or no improvement in blood values.

Based on results posted on this forum, and many reports I have seen of greatly improved energy levels for sickle cell patients and others long before blood values improve, I think carao may improve the body's transport of oxygen, allowing the body to make better use of its limited blood.

I am hopeful that thal minors and intermediates will see good improvements in blood values from carao.  Maybe someday we will have a real scientific study.

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