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beet as medicine in thalassemia

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nice friend:
i think this thread should be moved to the board name  " Diet, Nutrition and supplements "  . i think, it is the best place for threads like these . wat do you say Andy ??...

nice friend:
Hi Buddies ,
something  i want to share uder this topic is here ..

A quote From : http://en.wikipedia.org/wiki/Beets#Red.2Fpurple_colouring

--- Quote ---Red/purple colouring
The colour of red/purple beetroot is due to a variety of betalain pigments, unlike most other red plants, such as red cabbage, which contain anthocyanin pigments. The composition of different betalain pigments can vary, giving breeds of beetroot which are yellow or other colors in addition to the familiar deep red.[15] Some of the betalains in beets are betanin, isobetanin, probetanin, and neobetanin (the red to violet ones are known collectively as betacyanin).[bgcolor=#fff500] Other pigments contained in beet are indicaxanthin and vulgaxanthins (yellow to orange pigments known as betaxanthins). Indicaxanthin has been shown as a powerful protective antioxidant for thalassemia, as well as prevents the breakdown of alpha-tocopherol (Vitamin E).[/bgcolor]

Betacyanin in beetroot may cause red urine in some people who are unable to break it down. This is called beeturia. [16]

The pigments are contained in cell vacuoles. Beetroot cells are quite unstable and will 'leak' when cut, heated, or when in contact with air or sunlight. This is why red beetroots leave a purple stain. Leaving the skin on when cooking, however, will maintain the integrity of the cells and therefore minimise leakage

--- End quote ---

Best Regards
Take Care

nice friend:
quote from : http://www.ncbi.nlm.nih.gov/pubmed/16984002

--- Quote ---Cytoprotective effects of the antioxidant phytochemical indicaxanthin in beta-thalassemia red blood cells.

Tesoriere L, Allegra M, Butera D, Gentile C, Livrea MA.
Dipartimento Farmacochimico Tossicologico e Biologico, Università di Palermo, Via Archirafi 32, Palermo 90128, Italy. mal96@unipa.it

Antioxidant phytochemicals are investigated as novel treatments for supportive therapy in beta-thalassemia. The dietary indicaxanthin was assessed for its protective effects on human beta-thalassemic RBCs submitted in vitro to oxidative haemolysis by cumene hydroperoxide. Indicaxanthin at 1.0-10 microM enhanced the resistance to haemolysis dose-dependently. In addition, it prevented lipid and haemoglobin (Hb) oxidation, and retarded vitamin E and GSH depletion. After ex vivo spiking of blood from thalassemia patients with indicaxanthin, the phytochemical was recovered in the soluble cell compartment of the RBCs. A spectrophotometric study showed that indicaxanthin can reduce perferryl-Hb generated in solution from met-Hb and hydrogen peroxide (H2O2), more effectively than either Trolox or vitamin C. Collectively our results demonstrate that indicaxanthin can be incorporated into the redox machinery of beta-thalassemic RBC and defend the cell from oxidation, possibly interfering with perferryl-Hb, a reactive intermediate in the hydroperoxide-dependent Hb degradation. Opportunities of therapeutic interest for beta-thalassemia may be considered.

PMID: 16984002 [PubMed - indexed for MEDLINE]
--- End quote ---

Take Care
Umair

Sharmin:
Thank you for the info Umair.  Good work.

Sharmin

nice friend:
Thank you Sharmin Sis   :)

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