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abstracts about deficiences in Thalassemia

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ParkerLewis:
[bgcolor=#ff2700]β-Thalassemia and its effect on amino acid metabolism [/bgcolor]

http://cat.inist.fr/?aModele=afficheN&cpsidt=16428489

Thyrosin deficiency for example can possible lead to hypothyrodism,because Thyrosin is involved in Thyroxin main production.

[bgcolor=#ff2700]Serum carnitine levels in patients with homozygous beta thalassemia[/bgcolor]
http://www.springerlink.com/content/0q81qmxjdfu7jwly/

[bgcolor=#ff2700]Zinc and copper status of thalassemic children[/bgcolor]

http://www.ncbi.nlm.nih.gov/pubmed/9656419

This makes sense to me,because Copper is involved in red blood cell production,but this also means,that a deficiency in this mineral would be much worse,than it would be for normal people. Perhaps there is a connection between increased Iron absorbation in the gut and increased copper absorbation.

[bgcolor=#ff2700]Magnesium Status of thalassemic patients and rats [/bgcolor] http://www.haematologica.org/cgi/content/abstract/83/2/118
http://cat.inist.fr/?aModele=afficheN&cpsidt=2767209

[bgcolor=#ff2700]Folic acid and thalassemia [/bgcolor] http://www.ams.ac.ir/AIM/0693/0019.pdf

To be continued... :wink

Sharmin:
ParkerLewis,

Thank you very much for this information - I look forward to reading the rest :)

Sharmin

ParkerLewis:
 
effects of vitamin C and selenium on NK activity of patients with β-thalassemia
http://cat.inist.fr/?aModele=afficheN&cpsidt=17857285[/color]
The Benefits of Vitamin C and Vitamin E in Children with b-Thalassemia with High Oxidative Stress
http://www.mat.or.th/journal/index.php?command=preview&selvol=88&selno=4&selids=910

Important for Mayor Patients
Hemochromatosis and Vitamin Chttp://www.annals.org/cgi/content/full/131/6/476

Vitamin D, heart dysfunction tied in thalassemia
http://www.articlearchives.com/medicine-health/diseases-disorders-blood-anemia/259401-1.html

Low serum levels of 25-hydroxy vitamin D in adults affected by thalassemia major or intermedia
http://cat.inist.fr/?aModele=afficheN&cpsidt=17899816

Attenuation of oxidative stress-induced changes in thalassemic erythrocytes by vitamin Ehttp://cat.inist.fr/?aModele=afficheN&cpsidt=15649065

Important here: "The activities of enzymatic antioxidants viz. catalase, glutathione peroxidase and glutathione reductase were found to be drastically reduced in untreated Eβ- and β-thalassemic patients when compared to normal subjects"

The role of vitamin E in the therapy of thalassemia (mayor)
http://www.ncbi.nlm.nih.gov/pubmed/3725609

The effects of beta-carotene and vitamin E on erythrocytes lipid peroxidation in beta-thalassemia patients (mayor)http://journals.mui.ac.ir/jrms/article/viewArticle/1228

Effect of coenzyme Q10 as an antioxidant in β-thalassemia/Hb E patients
http://cat.inist.fr/?aModele=afficheN&cpsidt=18015389

Masked deficit of vitamin B12 in the patient with heterozygous β-thalassemia http://cat.inist.fr/?aModele=afficheN&cpsidt=16437129

Potassium permeability in β-thalassemia minor red blood cells
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=292232

Serum selenium levels in Greek β-thalassemia patients
http://cat.inist.fr/?aModele=afficheN&cpsidt=3408369

this stands in contrast to thal mayor patients with iron overload.
http://www.ncbi.nlm.nih.gov/pubmed/11393640

Increased sensitivity to the inhibitory effect of excess iodide on thyroid function in patients with β-thalassemia major and iron overload and the subsequent development of hypothyroidism
http://cat.inist.fr/?aModele=afficheN&cpsidt=1483474

You are welcome to add some new studies for sure...:)

Manal:
Parker Lewis

Thank you somuch for these valuable articles, i will spend some time to finish them all especially that my son was found defiecent in some of them.

Manal

nice friend:
Hi Parker Lewis ,
Good Going  :thumbs Nice & informative sharing buddy !! ....  :ty

Best Regards
Take Care
Umair

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