Discussion Forums > Diet, Nutrition and Supplements
Multivitamins for thal major children
Dori:
Thank you Andy,
For a few years I avoid vit c, but i did take it between meals.
I think I do understand the article...
Manal:
Andy, so i can understand that my son can drink juice (with added vitamin C) as well as citrus fruits right after the meal, as this fact was proven by the study. But what about the other fact that is Vitamin C helps in iron absorption?? In which form does this absorbed iron become ???
I don't get it because these two fact are contradicting!!!!
manal
Andy Battaglia:
Manal,
This study does contradict previous thinking about citrus and iron absorption. This study found no connection between citrus intake and serum ferritin levels. What is noteworthy is
--- Quote ---Although a model has been proposed in which greater fruit intake is associated with increased iron uptake and higher body iron stores,13,14,16 other large studies have provided little support for this
--- End quote ---
If the thinking that iron intake is increased by vitamin C intake is based on a model and not the result of studies, one may conclude that the model is wrong,
It should also be noted that red meat and alcohol both DO cause increases in serum ferritin levels.
Also,
--- Quote ---The protective effect of fruit is therefore potentially relevant to other important iron-overload conditions that do not involve HFE mutations, including thalassemia and sickle cell anemia. Approximately half of β-thalassemia major patients die before age 35 years, predominantly from iron-induced heart failure.27 Dietary modification might assist in optimizing dose regimens for new iron chelators now coming on the market to allow safer, more effective management of iron load.
--- End quote ---
This is very interesting that they feel that dietary considerations can have a significant impact on ferritin levels.
Manal:
Thanks Andy, the picture is more clear now :wink
manal
nice friend:
Hi Andy ,
Sorry , but ii m a little confused again , i want to ask abt the Vit-C and Ferriprox ,
as everybuddy know that Ferriprox chelate's stored iron from heart , it will b good to take Vit-C with Ferriprox ?? as vit-C used to mobilize iron ( release iron in blood ) . in this ccase , is Vit-C will effect to efficiancy of Ferriprox ??.... in this case Ferriprox will have less iron in heart to chelate .. please correct me if i m wrong .. i will b real thanlful of you . and sorry again for asking again & again abt Vit-C ..
Best Regards
Take Care
Umair
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