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Effect of L-carnitine on the physical fitness of thalassemic patients.

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Manal:
Sharmin, Lena and everyone

After asking doctor El Beshalawy about the reason for this dosing, she told me because they found in their studies that L-carnitine when taken daily causes depression of the bone marrow leading to aplasia and taking two days off avoid this to happen.

When i told her that some people take it daily, Dr. El Beshlawy said that they have to moniter their Hb and other blood products.

She said that another doctor in the States ( can not recall the name ) had the same result with his study of L-carnitine.

Andy, this year she will release her study about the positive effect of L-carnitine over PHT

All the doctor's studies are based on 50mg/kg but she told me that it can be taken up to 100mg/kg


I asked her if hydrea could lead to aplasia as found with L-carnintine, she said no because this is compansated by the induction of fetal Hb

By the way l-carnitinne release some fetal Hb too

manal

Lena:
Dear Manal,

is there any place I can find this study by dr. El Beshlawi? I told that to my hemo and she asked if I could pass her this study because she had read a study by dr.El Beshlawi that praised the advantages of L-Carnitine. According to my hemo, who has also studied the subject, carnitine lessens the intervals between transfusions as well as prolongs the survival of red cells.
She was surprised by what I told her about only 5 days a week and asked for this study, if there is one.

Lena.

Manal:
Lena, this does not at all contradicts with the benefits of L-carnitine and still Dr. El Beshhlawy praises it and insists on its importance. It is the way it is taken only which does not diminish anything of its benefits. I just want to make sure this note is clear

When i told her about you taking it everyday, she told me exactly that this is okay as long as you keep monitering all blood products

Next time when i see her i will ask her about any documented study about this finding

take care
manal

Lena:
Do not worry Manal, everything is clear to me. I did not get it wrong.I know the importance of Carnitine. I only wanted to clear this up with my hemo and she responded immediately and wants to take it further.So please, if this is not much trouble with you, ask her for anything I can pass on to my hemo.

Shokran.

maha:
Hi Manal
L-Carnitine is not available here :wah. One of the stores had something called acetyl L-carnitine. How same or different is it from L-Carnitine. Could you tell me the name of the brand you use. It should be available in the UAE, and I could get it from there.
thankyou
maha

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