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New Research Sheds Light On How Stem Cells Turn Into Blood Cells

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Dori:

--- Quote ---New Research Sheds Light On How Stem Cells Turn Into Blood Cells
07 Mar 2009   

Researchers funded by the Canadian Cancer Society have discovered how certain messages that are carried within stem cells can trigger those cells to become blood cells. The findings were published online on the 5th March 09 in Cell Stem Cell.

"This finding is exciting because it may provide a new way to make blood from human stem cells that could be used to regenerate the blood system in patients, including those with leukemia or those undergoing cancer treatments that indirectly destroy the immune and blood system," says Dr. Christine Williams, Director of Research Programs at the Canadian Cancer Society Research Institute.

This is the first time researchers have been able to show the importance of one particular cell pathway - known as the noncanonical Wnt pathway - in prompting stem cells to specialize and become blood cells. The pathway appears to organize the stem cells so that they can respond to signals telling them what to turn into.

Dr. Mick Bhatia, who led the study, received a $750,000 grant from the Canadian Cancer Society for this research. "By directing cell differentiation, this method provides the most efficient way to produce blood cells that we are aware of to date," he says. Dr. Bhatia is director of the McMaster University Stem Cell and Cancer Research Institute.

Stem cells are the building blocks of every organ and tissue in the body. These cells have the remarkable ability to become any type of cell in the body including bone, muscle and blood cells.

Notes:

The Canadian Cancer Society is a national community-based organization of volunteers whose mission is the eradication of cancer and the enhancement of the quality of life of people living with cancer. It is the largest national charitable funder of cancer research in Canada. Last year, the Society funded close to $49.5 million in leading-edge research projects across the country. To know more about cancer, visit the website at http://www.cancer.ca or call the toll-free, bilingual Cancer Information Service at 1 888 939-3333.

Source:
Christine Harminc
Senior Communications Officer
Canadian Cancer Society

Article URL: http://www.medicalnewstoday.com/articles/141400.php

Main News Category: Stem Cell Research

Also Appears In:  Cancer / Oncology,  Lymphoma / Leukemia,  Blood / Hematology, 
--- End quote ---

Right section?

Sharmin:
Thanks for the information.  I wonder if this could have an implications for thalassemia and other anemias. 

Sharmin

Dori:
Last night it was picked up by Dutch journalists and it was on teletext. Those daily awake bosses don't seemed too smart to understand what it meant or to call someone to explain it. It just disaappeared for the news!

Anyway, I did not understand the benefit of it too so I asked my father. When he heard I could only hear his voice and he sounded so happy.

If they can make blood from stem cells, they would be able in the future to do that also with your own stem cells.
If they succeed there comes a time that they can make those blood cells better than the ones your body makes....

In other words:It's a very good development!!!

Bonne jour!

Dore

Andy Battaglia:
Now that the ban on funding stem cell research has been lifted in the US, we can expect rapid advancement in this field. I do believe there will be very beneficial results from this research and for thals, creating red blood cells from stem cells is the most promising.

Andy Battaglia:
Let me add to what I just posted. Stem cell research holds promise for anyone with a blood disorder (not just thal) where there body does not make proper red blood cells. I can understand why Dore's dad would be excited by this.

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