Discussion Forums > Thalassemia Major

Financial assistance for Bone marrow transpant

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Madhavi:
Dear Ajinkyanahar,

Wish you all the best for the procedure....
Our best wishes are always with you....

Regards,
Madhavi

HEMANT:
i have a baby 10year old boy suffering from t/major blood transfussion start from after 8 month of his bon now i can discuss to bonmarrow transplant of our baby can you guide me where in india his treatment 100% posssiable or what is the total cost today & any orgnigation donate or sponer the 75% cost of bonmarrow.advise us urgently please thanks in advance

Narendra:
Hemant,

Thalassemia is not as fatal as it used to be. There has been tremendous advances in the management of Thalassemia and Thals have crossed the age of 50 and I even read the story of a thal reaching 60.

In response to your question, there are multiple centers in India that do BMT and the cost/success ratio (as anyone would guess) is different for each case. The 1st step towards BMT is to find a matching donor. CMC Vellore is one center I know where a lot of BMT have been done. Although, the guru of BMT at CMC has left the hospital and moved to Tata Medical Center. Regarding the cost breakdown - it is roughly around 12-15 lac rupees but again with different cases, there are changes in the cost.

Here are few links that will help you get some information on the basics of BMT.

From : http://www.thalassemia.com/bmt_2.html

--- Quote ---What is involved in obtaining a bone marrow transplant for thalassemia major?
The biggest obstacle is finding the donor for the transplantation. Since beta thalassemia major is no longer considered a fatal disease, criteria for donation differs from the criteria for BMT for a patient with a fatal disease such as cancer. Usually a patient suffering from cancer is given very toxic chemotherapy to kill the cancer cells and then is "rescued" from the chemotherapy with a bone marrow transplant. In the case of thalassemia, the goal of the chemotherapy is to remove most or all of the blood forming cells (stem cells) from the recipient and replace them with donor stem cells in order to repopulate the bone marrow space and make new, normal blood cells. In a cancer patient, the 'best' (genotypic) match is used for the transplant. In a b thalassemia major patient, the match must be the 'perfect' (HLA-identical) match. The closest perfect match is usually a sibling who has the same antigenic makeup (is HLA identical to the recipient) as the individual who has thalassemia. There is only a one in four chance a sibling will have the required immunologic criteria for a bone marrow donation. There are many children who have thalassemia who have no siblings or no siblings who are HLA-identical for donation.

Generally speaking, the younger the recipient, the more optimistic the outcome. The Lucarelli Staging System is based on the amount of liver damage sustained as a consequence of iron overload from chronic transfusion therapy and the adequacy of Desferal chelation therapy. The staging includes evaluations of liver size, the schedule and compliance of desferrioxamine therapy, and liver biopsy (in children over 3 years) to determine whether or not there has been microscopic liver damage.
--- End quote ---

Risks of BMT and CBT :  http://www.thalassemiapatientsandfriends.com/index.php/topic,2919.0

Transplant Experience of a family : http://www.thalassemiapatientsandfriends.com/index.php/topic,3125.0

HEMANT:
how many risk percentage in bonmarrow out of 100% & ist is total time spend in this process like one month two month six month or one year

HEMANT:
please guide me

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