Discussion Forums > Thalassemia Major

Any info about Liver Issues in Thal Major children???

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Cari:
Hi all,

A friend of mine has a 5 year old little girl who is in the hospital. I don't know all the details but apparently she went in complaining that she had stomach pains.  At first, they thought it may be a blood infection or her kidneys.  Now they are saying she is having some kind of liver issue.  I can post more as I get more information but if there are any older topics relating to this issue for thal majors please let me know.

Also, if you may have any insight on this - let me know.  I believe she started to be transfused around 1 year old.  She may also post - but I wanted to get it started in case she doesn't have a chance. 

THanks in advance

Andy Battaglia:
Is she on Exjade?

Cari:
Yes

Andy Battaglia:
OK. I ask because often thals are being treated in emergency situations by doctors unfamiliar with thal or its treatments. If they are not already aware, the doctors should be told about the liver and kidney function issues that can arise with Exjade use. Her creatinine and ALTs should be tested. If they are high, Exjade is the likely cause and should be temporarily stopped.

Sharmin:
The liver and gall bladder are quite close in proximity - gall bladder issues are more common in this age group than liver - I'm sure the docs have considered this - but I wonder if there is a relation. 

As Andy said, Exjade may be having an effect on the liver. 

Sending my best to your friend's little girl, please keep us posted,

Sharmin

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