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How old the pack cell can be used

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ANI:
Dear All
Pl help me in understanding that how old that pack cell can be used. In our blood bank, we are ,at times ,gven blood which is  as old as 30 days. They say that the expiry date is 40 days from date of collection. My question is that will this blood be as effective as the fresh blood . Are we doing the right thing by transfusing this blood.
what is the way out. Feeling helpless. The gene therapy is also lookig like distant dream and on top of that these blood related issues.
Rgds

ANI:
Dear Andy
 Request someone you to answer my query, please.

Andy Battaglia:
Blood can keep for up to 40 days. Practical experience tells us that the fresher the blood, the longer its life will be in the recipient's body. Sometimes you have no choice. Older blood may not be quite as effective, but it is still useful. One way to avoid this is to arrange a group of donors, so that blood can be made available when needed.

JV:
Andy...my daughter goes to CHOP every 3 weeks (on fridays) for her transfusions. The last 2 times she has had a high fever the day after which lasted a few days and reached a temp of 103. Could this be a result of the blood used? Im interested in knowing how old the blood is that they use at CHOP.

Thanks,

James

ANI:
Thanks Andy for the clarification. One of my observation is that when the blood is frsh the spleen size of my son reduces and when it is not so , it usually becomes hard.

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