Discussion Forums > Working Towards a Cure
Gene Transfer Therapy Stage 1 Clinical Trials at Sloan Kettering
Sharmin:
Thank you for sharing Canadian Family. I am praying for this because of the reduced intensity preparation required as compared to blue bird.
Parin:
Thank you Canadian Family for sharing with us.
Canadian_Family:
--- Quote from: Sharmin on October 01, 2015, 03:14:37 AM ---Thank you for sharing Canadian Family. I am praying for this because of the reduced intensity preparation required as compared to blue bird.
--- End quote ---
Hi Sharmin,
I agree with your assessment. This approach uses low intensity preparation which is much safer, I am more inclined towards this approach compared to Blue Bird's. What I am still not sure is the involvement of Dr. Michel Sadelain in these trails. Last I heard from Andy was that he has its own Bio venture and there were some tension between MSKCC and him. We also have no update from Pat Girondi for a while now. I hope silence brings good news in future for us.
DrRajpal:
--- Quote from: Andy on July 10, 2014, 06:42:56 PM ---I just got off the phone with Pat Girondi. They have a meeting come up soon and we should be able to get more information after that. He did tell me that the first two patients who started at SK have a greatly reduced transfusion regimen now, and a third patient in his 40's has had some gene expression but less than is needed. It may be that a higher dose is needed in older patients. Keep in mind that these are all beta thal majors and not HbE beta thals, as the early patients that Bluebird has treated are.
--- End quote ---
hello sir
its now oct. 15 ,
how much the team have proceeded, and what we can expect of the best?
Andy Battaglia:
I don't know if Sadelain is still involved with gene therapy at SK. Sadelain became part of a group that started a new company directing research towards gene therapy to cure cancer. This company then had a huge influx of funds from a large pharma company, which I believed created a large windfall for all involved.
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