Discussion Forums > Thalassemia Major

List of all regular tests for Thal major

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anshul:
Thanks Prateek.

Currently, with every transfusion, only Hb is checked. Do i need to ask for other test like  SGPT/SGOT (ALT/AST). Heis 9 months old now.

Pratik:

--- Quote from: anshul on November 26, 2012, 05:53:56 AM ---Thanks Prateek.

Currently, with every transfusion, only Hb is checked. Do i need to ask for other test like  SGPT/SGOT (ALT/AST). Heis 9 months old now.

--- End quote ---
Yes, especially monitoring SGPT/SGOT after starting chelation. SGPT and SGOT are liver and kidney functions respectively. When using chelators, the load on them increases and that is why keeping your child hydrated is most important. Thus, you should get done SGPT and SGOT both done every time a transfusion is planned.

Normally, a thal major's SGPT can be up to 4X times larger than norms, but if it increases (when using chelators) above 140 or so, chelator's dose should be decreased or discontinued for 2-3 days.

-P.

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