Discussion Forums > Thalassemia Major

Planning to try Hydroxyurea. Have few questions.

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Andy Battaglia:
Especially because of the fertility issues, I would recommend against it, at least until your physical development is judged to be normal.

Dharmesh:
This trial done on Hydroxyurea in B thals..

http://www.ncbi.nlm.nih.gov/pubmed/21602718

Rashmi:
Hi Pratik,

I am on and off hydroxyurea since 2001. It did not increase my Hb level and as it has fertility issues, it was stopped.

Last year on I am again on it- this time not for HB but for my bad back. Will go for a review next month. Will get to know the exact position then.
But it has not improved my Hb or the transfusion gap. I am an intermedia.

Pratik:
Thanks for the feedback Rashmi.

I actually decided not to take it due to the same issues.

-P.

b_dcruze:
Dear Andy & Pratik,

My son in 3 years 2 months old. He has been diagnosed with Thal Major, but till now he has been behaving as a Thal intermediate. He has maintaining a healthy Hb level of 8+ without transfusion till May 2013. However, his Hb level has fallen to 7.0 in June and further to 6.9 in July end. My doctor has advised to use Hydroxyurea. I have a few questions regarding this :

1. He is 3 years old and has never been transfused, is it safe for him.
2. What are the side effects on his health and growth
3. He is 13 Kgs now, if I use what is the dosage and amount that should be given.

Please advice

Regards
Benjamin D
Kolkata

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