Discussion Forums > Thalassemia Major

when blood required is between Paediatric and Adult bags

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zahra:
Hi Andy,
 My son had his transfusion today. He needs 380ml by 20 ml /kg rule.
Paediatric units are around 300ml and adult 500.
Choices are to use two Paediatric units and expose him to antigens from 2 donors or to bring him in earlier which would be2-3 weeks instead if 3-4 weeks.
This problem will continue till he is about 25 kg I guess and qualifies for the adult unit.
What is the standard and which would you recommend?
Zahra

Andy Battaglia:
Hi Zahra,

My ideal standard would be once weekly, which of course is not practical, but you see my direction. I would prefer minimizing the amount of donors, so taking blood one week earlier would be my advice. If there is any consideration at all about pursuing a BMT at any future point, this would become even more important, as exposure to fewer antibodies means less chance of reaction to the new bone marrow.

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