Discussion Forums > Thalassemia Major

I v desferal taken how long

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jatin:
Hi all I have query pls reply and share experiences.
One of my know thal major patient ferrtin is around 6500 from last 2 yrs.
T2 * mri of heart is 11.0 ms
T2 * mri of liver is severe around 1
T2* mri of pancreas is 3.3 severe.
Patients is on deferasirox 500 mg 4 tabs.
Weight is 40 kg ..
He has taken inj.desferal  for sat sun by pump for around 6 months .
Pls suggest what is max numbers of days I'v desferal can be given .thanks

Andy Battaglia:
IV desferal is usually given for no more than two weeks at a time, unless the patient is in heart failure. In between IV sessions, pumping should continue at least 5 times per week. The patient's dose of deferasirox is too low. With those iron numbers, the patient should be on high dose of at least 40 mg/kg daily. For this patient, it should be 1600-2000 mg daily, split into two doses to maximize the benefit. It is critical that aggressive chelation be undertaken for at least two years.

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