Discussion Forums > Working Towards a Cure
Red Grapes
Bharat:
Very Interesting
Thanks Manal and Andy.
Bharat
Manal:
Andy i read that Resveratrol is available as a nutritional supplement, is it okay for thal to take a pill daily ?? Is there any negative side effects for pills??
Manal
Andy Battaglia:
Resveratrol is sold as a nutritional supplement. There are no known side effects or reactions with drugs. It is found in many foods, two of which that have high amounts are grapes and boiled peanuts. The resveratrol is found in the skins. It is known to have many healthful properties, and is suspected to be a cancer preventative. It is also a blood thinner, like aspirin and vitamin E, so anyone using a blood thinning drug like warfarin or coumadin should ask their doctor before using them. And just like the others, it should be stopped one week before any surgery. Thals generally have some danger of clotting so a mild natural blood thinner can often be of some benefit to thals.
Food products such as wheatgrass extract and resveratrol are made from simple foods that people consume regularly. I feel they are very safe and may have beneficial properties.
A very good analysis complete with a chart showing how much resveratrol is found in different foods, can be found at http://lpi.oregonstate.edu/infocenter/phytochemicals/resveratrol/
--- Quote ---Resveratrol
Summary
* Resveratrol is a polyphenolic compound found in grapes, red wine, purple grape juice, peanuts and some berries. (More Information)
* When taken orally, resveratrol appears to be well-absorbed by humans, but its bioavailability is relatively low because it is rapidly metabolized and eliminated. (More Information)
* Scientists became interested in exploring potential health benefits of resveratrol when its presence was reported in red wine, leading to speculation that resveratrol might help explain the “French Paradox.” (More Information)
* Moderate alcohol consumption has been consistently associated with 20-30% reductions in coronary heart disease risk, but it is not yet clear whether red wine polyphenols, such as resveratrol, confer any additional risk reduction. (More Information)
* Although resveratrol can inhibit the growth of cancer cells in culture and some animal models, it is not known whether high intakes of resveratrol can prevent cancer in humans. (More Information)
* Resveratrol administration increased the lifespans of yeast, worms, and fruit flies, but it is not known whether resveratrol will have similar effects in higher animals or humans. (More Information)
* At present, relatively little is known about the effects of resveratrol in humans.
Total Resveratrol Content of Wines and Grape Juice
Beverage Total resveratrol (mg/liter) Total resveratrol in a 5-oz glass (mg)
White wines (Spanish) 0.05-1.80 0.01-0.27
Rosé wines (Spanish) 0.43-3.52 0.06-0.53
Red wines (Spanish) 1.92-12.59 0.29-1.89
Red wines (global) 1.98-7.13 0.30-1.07
Red grape juice (Spanish) 1.14-8.69 0.17-1.30
Total Resveratrol Content of Selected Foods (73, 75, 89)
Food Serving Total resveratrol (mg)
Peanuts (raw) 1 cup (146 g) 0.01-0.26
Peanuts (boiled) 1 cup (180 g) 0.32-1.28
Peanut butter 1 cup (258 g) 0.04-0.13
Red grapes 1 cup (160 g) 0.24-1.25
--- End quote ---
Manal:
Andy i read,
'"that taking resveratrol is not recommended for growing children and pregnant females. Since the ingredients in Longevinex ( this med has resveratrol ) may inhbit the action of protective enzymes in the liver (called cytochrome P450 enzymes), "
Also i read
"Safety Issues
Resveratrol has estrogenic effects and, according to one study, might stimulate the growth of breast cancer cells.15 For this reason, it should be avoided by pregnant or nursing women as well as women who have had breast cancer or are at high risk of developing it. Combination therapy with prescription estrogen is not recommended. Maximum safe dosages for children, pregnant or nursing women, or those with severe liver or kidney disease have not been determined. "
SO Andy , does this mean that i can n't give these tablets to my son. I am trying to feed him red grapes, but his intake is very limited. I also asked my heme about resveratrol, but she said that she knows nothing about this and asked me to print her what i read about it from the internet in my next visit.
So what do you think??
Manal
Andy Battaglia:
Hi Manal,
The effects of resveratrol on estrogen are somewhat contradictory, because it may stimulate or inhibit the estrogen receptors depending on other factors. However, keep in mind that it may not have much relevance to your son, as estrogen is a problem for females because they have ovaries that produce estrogen. Resveratrol does inhibit the cytochrome P450 enzyme and this is actually from what its anti-cancer properties are derived, as P450 enzyme is over expressed in many tumors. There is much evidence that resveratrol may inhibit many types of cancers.
The concerns about children taking resveratrol is that it hasn't been studied on children so the maximum dose is not known. A low dose like what you suggested for your son seems to be safe. Can he eat peanuts? They also have high levels of resveratrol and the diet is always the first route to good nutrition.
Navigation
[0] Message Index
[#] Next page
[*] Previous page
Go to full version