Discussion Forums > Thalassemia Major

E/Beta Thalassemia

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Md. Abdul Hakim:
Dear Andy
I don't get L-Methail Folate but have got only methaile Folate instead of L- Methaile Folate .
Could I use Methaile Folate for my two years baby? 
Is L-Methail Folate and Methail Folate same?


Regarding
Md. Abdul Hakim
 

Andy Battaglia:
They're the same thing.

Md. Abdul Hakim:
Dear Andy sir
My daughter age is now four.
we are decided to do  BMT . But we don't fiend HLA match donor. My wife brother HLA sample is Half matched (5/10 ) but my 2nd baby(sibling little sister of ZARA) HLA is not matched(0/10). How is it possible?
Dear Andy sir could you please explain:
1. Is it  possible to 100% mismatch with her sibling(little sister)?
2. ZARA has completed 13th Transfusion last month. She have to get one transfusion per month so that maintain Hb level at 9 g/dl. After Blood transfusion she often got high fiver within 6 to 12 hours(some time 103.5 to 4.0 [0][/F] even though I used wash blood and leukocyte filter.
Why does it happen? and How can I relief from it ?
My daughters HLA test report are attached below  :

Andy Battaglia:
I don't see how it's possible for a biological sister to be a zero match. Matched unrelated donors may be the best avenue to proceed.
Is anything given to the daughter before transfusion, like Benadryl? It may reduce the reaction. Closer matching of the transfused blood may also help.

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