Thalassemia Patients and Friends

Discussion Forums => Thalassemia Intermedia => Topic started by: AL on May 13, 2008, 09:38:35 AM

Title: Latest Update On AQEEL
Post by: AL on May 13, 2008, 09:38:35 AM
Hi guys!

My son had high fever (reached 41 degrees) due to that his HB dropped to 6.2. Were were at the hospital for few days waiting for his fever to subside and eventually it does. Blood transfusion was done a few hours ago (today) but [bgcolor=#ff3a00]had to be stopped [/bgcolor] due to the fact that it appears that there are red spot appearing all over his body.

Now the doctor had requested for his urine sample to do further checkings! [bgcolor=#ff0000][/bgcolor]

My questions is does this normally happened? Why is this happening?  Should i be aware of anything else?

Please help u guys on any informations,, coz this is the second time he had blood transfusions,,the first time everything went smoothly!

Really appreciate it.

Title: Re: H.B 6.2
Post by: maha on May 13, 2008, 02:10:30 PM
Hi AL
Skin rashes are allergic reactions associated with the donor blood. They occur when antibodies in the patients blood react to proteins in the plasma of the donated blood. If the reaction is mild then it can be treated with antihistamines. I do not know how such reactions can be avoided though :dunno. Most reactions usually can be avoided by using a leucocyte reduction filter. By the way was a filter used when Aqeel was transfused the first time.
take care
maha
Title: Re: H.B 6.2
Post by: AL on May 13, 2008, 11:51:54 PM
Thanks Maha!

The 1st time transfusion they did use filters. I came to know that they did not use filters for the 2nd time. Somehow rather they forgot  :huh!

Anyway, the spots are almost cleared now. Now my wife is at the hospital waiting for the 3rd (hopefully the final) transfusion.

By the way, my son is taking wheatgrass at the moment! Any advise on to what else can he also take with that? He is now 18 months old and his weight is 12kg!

I heard about Hydroxurea and Resveratrol?  :huh
Seriously, I dont really know about these 2! Can anyone briefly describe these in a lay man term?

Thanks U all!



Title: Re: H.B 6.2
Post by: Andy Battaglia on May 14, 2008, 02:06:23 AM
Hi AL,

Resveratrol is a natural supplement made from red grapes. It is also a hemoglobin inducer that can be used with wheatgrass. Hydroxyurea is a drug that is also a hemoglobin inducer and it can be taken with the other supplements. However, it is a drug, and must be taken under a doctor's supervision.

I am certain the spots were a reaction to the unfiltered blood. Often, an antihistamine like benadryl, is taken along with the transfusion to minimize this type of reaction.
Title: Re: H.B 6.2
Post by: AL on May 14, 2008, 04:56:24 AM
Thanks Dr. Andy!  :biggrin

I will later ask about it with the doctor at the hospital! Either to give or not to give? Ask for their opinion on it.

That u all  :hugfriend

Later
Title: Highest H.B so far 9.4
Post by: AL on July 02, 2008, 01:41:31 AM
Hi all! :biggrin

I was really up beat when i got to know that my son HB was 9.4 a few weeks back! Infact, instead of our normal monthly check up, the doctor told us to come and see her again in 2 months time! Should i stick to once a month basis or as suggested by the doctor to have it once in 2 months?

His recent HB level made me wonder, is it possible that his hb increased further? Coz all the while i thought that his HB would be within the range of 7 - 8.

Maybe its the wheatgrass! Sure hope so! but am not sure for certain!

I'm trying to determine how and why his HB increased! Any Opinion on this!

My son is now 20 months old and his weight is 12.5 kg!

Thanks u all
Title: Re: H.B 6.2 (Now 9.4)
Post by: Andy Battaglia on July 02, 2008, 02:18:53 AM
Hi Al,

Some patients respond better to fetal hemoglobin inducers than other patients. It's early and probably too early to say anything for certain, but this is a positive sign. Although it may take a full year of use to judge the full effects of wheatgrass, some improvement is often shown much earlier. Keep it up and never slack. It does have positive effects beyond raising Hb and better overall health is mentioned by many patients using wheatgrass.
Title: Re: H.B 6.2 (Now 9.4)
Post by: AL on July 02, 2008, 04:51:14 AM
Thanks Dr. Andy!  :biggrin
Title: Re: H.B 6.2 (Now 9.4)
Post by: sah on July 02, 2008, 06:22:41 PM
Congratulation AL.I am soooooooooo happy for you.I was eagerly waiting for your posting to know about Aqeel latest hb level.Really AL I am so very happy and overjoyed.May GOD bless little Aqeel and  all other thals. :yahoo :clap :flowers
Title: Re: H.B 6.2 (Now 9.4)
Post by: AL on July 03, 2008, 03:32:49 AM
Thanks Sah!

Sure hope that his HB raise further!  :biggrin
Title: Re: H.B 6.2 (Now 9.4)
Post by: §ãJ¡Ð ساجد on July 03, 2008, 01:51:33 PM
:woot

I'm so happy to hear that he's doing nice :)

:party
Title: Re: H.B 6.2 (Now 9.4)
Post by: AL on July 07, 2008, 12:35:56 AM
Thanks Sajid!

Sure hope that his next check up in August, would be much BETTER!  :biggrin


اَسّلامُ علیکم
Title: Re: H.B 6.2 (Now 9.4)
Post by: sah on July 07, 2008, 04:24:13 AM
Please keep us updated AL.Praying to hear good news again in the month of August.Ameen. :pray
Title: Re: H.B 6.2 (Now 9.4)
Post by: Sharmin on July 07, 2008, 05:06:41 AM
I am wishing you all the best Al, I am sure you will continue to hear good news:) 

take care,
Sharmin
Title: Re: H.B 6.2 (Now 9.4)
Post by: Manal on July 07, 2008, 11:55:07 AM
Congratulations,  :hugfriendplease keep us updated and keep it up :wink

manal
Title: Re: H.B 6.2 (Now 9.4)
Post by: AL on July 08, 2008, 12:18:30 AM
Thanks Everyone!

No worries! I'll keep you all updated. For SURE!

 :biggrin
Title: Re: H.B 6.2 (Now 9.4)
Post by: AL on August 14, 2008, 07:37:27 AM
Hi everyone!

It's been a while since i logged in. Just that i'm busy with work etc.

Just to inform everyone that Aqeel's next appointment is on 22nd August. Frankly speaking, i am very eager to see his result becoz the last time he visited the hospital was way back in (June,,,,,as if, it is that long  :biggrin ). Normally he has appointment on monthly basis.

Lets pray together that his HB maintains above 9.4 and NOT LOWER!

Will keep u guys updated!

Later
Title: Re: H.B 6.2 (Now 9.4)
Post by: nice friend on August 14, 2008, 10:27:13 AM
WISH YOU ALL THE BEST AL ...
and your SON AS WELL... :goodluck
Title: Re: H.B 6.2 (Now 9.4)
Post by: §ãJ¡Ð ساجد on August 14, 2008, 12:28:54 PM
Wishing you all the best :)
Title: H.B Down from 12 to 9.4! Now 7.2
Post by: AL on August 22, 2008, 06:50:50 AM
Hi all! :biggrin

I was really up beat when i got to know that my son HB was 9.4 a few weeks back! Infact, instead of our normal monthly check up, the doctor told us to come and see her again in 2 months time! Should i stick to once a month basis or as suggested by the doctor to have it once in 2 months?

His recent HB level made me wonder, is it possible that his hb increased further? Coz all the while i thought that his HB would be within the range of 7 - 8.

Maybe its the wheatgrass! Sure hope so! but am not sure for certain!

I'm trying to determine how and why his HB increased! Any Opinion on this!

My son is now 20 months old and his weight is 12.5 kg!

Thanks u all

Hi everyone!

I just came back from the hospital and found that Aqeel H.B is 7.2. The doctor advised us make a revisit in 3 weeks time. For the record, Aqeel's weight increased (now 13.3kg) and his height also increased above the normal average height curve. Just that his HB is now 7.2. The doctor said that his spleen is slightly swollen (if i'm not mistaken as i were told by the doctor). Any advise on this?  :pray

Well, Remember the post of mine earlier? That i thought that Aqeel's H.B increased? Well it seems that his hb has never increased as i thought & hope so. I totally forgot that my son did have a transfusion in May, because of that his H.b in June was 9.4! Maybe because of the excitement of thinking his H.B increased, i totally forgot about his previous transfusion.  :-\  :wah. What was i thinking?
 :banghead :banghead

Now, i totally believe that Aqeel H.B, will be in no matter what in the range of 7-8 only. I will still continue with wheatgrass and at the same time try whatever i can try for others (perhaps colostrum).

What a day! :sulk




Title: Re: H.B from 6.2 to 12 after BT, then 9.4, NOW 7.2
Post by: sah on August 22, 2008, 09:35:15 AM
Hi Al,
I had a feeling that because of Aqeel's tx in the month of May,his hb is sure to be on higher side in June .But I did not wanted to depress you considering my own situation.Have faith in GOD,hope a cure of this disorder comes very soon.Please ask your doctor regarding hydroxyurea treatment,resveratrol.Take care and lots of love and hugs to Baba Aqeel.

Title: Re: H.B from 6.2 to 12 then 9.4, then 7.2 NOW 6.2
Post by: AL on September 03, 2008, 12:07:11 AM
Hi everyone!

Just want to update on Aqeel! Went to the doctor last week because he had high fever (above 40). We were prepared to admitt him that day but the doctor said Aqeel's tonsillitis is swollen and maybe its because of that and also because of teething. One of the reason she concluded that is because, when given medecine his fever reduced straight away. His HB then was 6.2.

Now, the doctor told us to visit her again in 2-3 weeks time. By the way, Aqeel at the moment are not having any fever. Thank GOD! Alhamdulillah! Sure hope that, in his next visit, his HB would increased!

Is it common for intermedia (child esspecially) to have fever so often? I'm trying to study this to try to make sure Aqeel does not has fever so often. It seems that every time he had fever his HB would definitely be at a LOWER level!

Later

Title: Re: H.B from 6.2 to 12 after BT, then 9.4, NOW 7.2
Post by: §ãJ¡Ð ساجد on September 03, 2008, 02:57:55 AM
Wishing you all the best!

I guess it's the tonsils that are causing all the trouble and making the HB down. I hope he gets well soon :getwell

:pray
Title: Re: H.B from 6.2 to 12, then 9.4, then 7.2, NOW 6.2
Post by: Manal on September 03, 2008, 03:57:47 AM
I have the same concern, does fever always cause hemolysis even if it is for just one day or a mild one as was the case with my son a week ago?

What is the frequency of hemolysis? Is it known or it is the nature of each one's body?

thanks

manal
Title: Re: H.B from 6.2 to 12, then 9.4, then 7.2, NOW 6.2
Post by: Sharmin on September 03, 2008, 04:17:24 AM
All the best to your son - I hope he feels better soon and that his hg increases. 

Manal, my son's hg drops when he has a fever.  I wonder if the increased immune activity causes more hemolysis when a fever is present. 

Sharmin
Title: Re: H.B from 6.2 to 12, then 9.4, then 7.2, NOW 6.2
Post by: §ãJ¡Ð ساجد on September 03, 2008, 05:40:45 AM
Well fever is the release of energy when cells break up. So hemolysis could be a pretty good culprit for the phenomenon. Remember our posts regarding Thals feeling warmer in winter. :dunno
Title: Re: H.B from 6.2 to 12, then 9.4, then 7.2, NOW 6.2
Post by: hopefulmommy on September 03, 2008, 03:40:07 PM
Hi,

I did read sometime back that HbE is unstable beyond 39 degree centigrade,so during fever episodes, the Hb level is likely to go down.

From general thought is it could be a good idea not to expose Aqeel to higher tempeartures or hot surroundings, and maybe monitor home temperatures. This is just a thought, but I am trying to do that for my daughter.

Does his fevers come form cold, like is he prone to catch cold easily and then have fever?

Best wishes
Title: Re: H.B from 6.2 to 12, then 9.4, then 7.2, NOW 6.2
Post by: Andy Battaglia on September 03, 2008, 03:43:20 PM
One of the common causes of hemolysis in transfused thals is antibody reactions to the blood. Infections can also be a cause, so in this case, the tonsils may be the problem. Treatment with antibiotics may be necessary if it recurs. Both the infection which causes fever and the hemolysis, as Sajid said, can cause fever. The breakdown of red cells does give off heat and fever is also common when fighting infection. The proper thing to do is to treat the source of infection in this case. If the tonsil infection subsides but the fevers continue, antibody reactions to the transfused blood should also be investigated. Folic acid, magnesium and vitamin E may also be of some help.

Not all infections cause hemolysis but some do but with thals I think hemolysis is more likely because the increased activity of the spleen during infection will most likely also filter out more red blood cells which will cause a drop in Hb. Improving the health of red blood cells through the use of supplements may reduce the amount of RBCs that are filtered by the spleen.
Title: Re: H.B from 6.2 to 12, then 9.4, then 7.2, NOW 6.2
Post by: olivia mary on September 03, 2008, 10:56:47 PM
Hi everyone..... :dunno  should the blood always be filtered before a tx?  Hi AL....you son sounds alot like Olivia.....It is always something with her.....she to has had 3 tx and during the 3rd one she swelled and broke out in a bad rash...they stopped the tx and gave her meds she was ok in a few hrs. We are going back on the 10th....they will pre-treat her and "wash" the blood. I hope she does good...
Good luck to your son and family....you are all in my prayers :grouphug
 Kathleen
Title: Re: H.B from 6.2 to 12, then 9.4, then 7.2, NOW 6.2
Post by: AL on September 04, 2008, 09:14:36 AM
Thank You Everybody!

Now i'm worried about Aqeel's spleen. What should i be expected of? Any experience to share?

He'll be 2 years old in 2 months time!

Later
Title: Re: H.B from 6.2 to 12, then 9.4, then 7.2, NOW 6.2
Post by: Zaini on September 04, 2008, 03:23:29 PM
Andy,

Do you think that starting continuous transfusions can solve the spleen issue,in Aqeel's case? And do you think maintaining hb as low as 7 is better then starting transfusions?

Zaini.
Title: Re: H.B from 6.2 to 12, then 9.4, then 7.2, NOW 6.2
Post by: Andy Battaglia on September 05, 2008, 03:26:24 AM
Reducing spleen size is one of the goals of regular transfusion, along with supplying sufficient oxygen to the body and resting the bone marrow so that the bones don't expand and weaken from excess activity.

The thinking about the treatment of thalassemia has changed greatly this decade and keeping patients as close to a normal hemoglobin level is now recognized as essential for normal growth and development and also for normal organ function that will not occur in an oxygen starved state. With advances in treatment and especially chelation, utilizing a higher threshold for Hb is now practical as long as chelation compliance is well maintained.

What concerns me about Aqeel right now is the frequent drops in Hb. At such a young age, there is so much development taking place that may be stunted by low hemoglobin levels. I feel that regular transfusions will be required unless other methods such as wheatgrass and hydroxyurea can prove successful in raising the HB. I have to agree that striving for normal Hb and normal growth is best in the long run, as the patient will be healthier with normal bone and organ development. I think antioxidants also must play an important role in protecting the organs from damage caused by accumulating iron deposits.

Kathleen, thals should receive only red blood cells and it should be filtered to help protect against transfusion reactions.

http://www.redcross.org/services/biomed/blood/supply/ulr/factsheet.html

Quote
What are leukocytes?
Leukocytes are white blood cells, one of the types of cells in human blood. The body produces leukocytes to help fight off foreign substances in the body such as bacteria, viruses and abnormal cells in an effort to avoid sickness or disease. However, when leukocytes are transfused into another person, with red blood cells, platelets or plasma, they are not well tolerated and have been associated with some types of transfusion reactions.

What is leukocyte reduction?
Leukoreduction is the removal of contaminating white blood cells from blood products. The most common method of leukocyte reduction is filtration. In this process, blood is passed through a filter that separates leukocytes from other blood components, based on their size and stickiness.

There are three types of filtration that may occur:

    * Prestorage leukocyte reduction:
          o In this preferred process, filtration occurs at the blood center soon after the blood is collected and is performed using standardized, quality controlled processing methods designed to produce a consistent level of leukocyte reduction.
    * In-lab post-storage leukocyte reduction:
          o Filtration occurs after the blood has been delivered to the hospital.
    * Bedside leukocyte reduction:
          o Filtration occurs at the patient's bedside as the transfusion is being given.

What are the benefits of leukocyte reduction?
Leukocytes contained in whole blood can act as a contaminant when transfused into a recipient, causing reactions that range from mild to potentially harmful. Leukocytes in transfused blood have also been associated with more serious problems, such as transmission of certain viruses, including cytomegalovirus (CMV), a common virus affecting more than half of all North Americans, and human T-cell lymphotropic virus (HTLV-I/II) which may cause blood or neurological diseases. Leukocytes have been known to cause the formation of antibodies that make future transfusions less likely to be effective and more likely to cause an adverse reaction.

By removing leukocytes from whole blood, the incidence rates for febrile (fever) transfusion reactions are significantly reduced for patients susceptible to this reaction, and may result in improved patient outcomes, shorter hospital stays and reduced health care costs.
Title: Re: H.B from 6.2 to 12, then 9.4, then 7.2, NOW 6.2
Post by: Zaini on September 05, 2008, 03:16:40 PM
Hi AL,

I think you should consider what Andy said,when there isn't enough blood in the body and enough oxygen,it will definitely effect body system in so many ways,every organ will have to work hard,you may not see any difference in his growth right now,but keeping low hb may create problems in the long run.I know before starting transfusions,it seems like a scary idea,but once you see the changes in your kid,you'll agree that it's better for him.

Wishing Aqeel all the best,

Zaini.
Title: Re: H.B from 6.2 to 12, then 9.4, then 7.2, NOW 6.2, Back to 7.1
Post by: AL on September 18, 2008, 06:17:59 AM
Hi everyone!

Just to update about Aqeel's condition! Well, last Friday we went for the needed check-up and Aqeels HB was 7.1.

I thought as first that we wont be needing BT but the doctor told us to get some "top up"  :huh. So for the record, Aqeel went for his BT last Friday.

You are right Zaini, after seeing Aqeel changes after the BT, i agree with you that it is the best for him. I am still continuing with the wheatgrass as i have not receive the Caroa juice. Maybe after a year of using wheatgrass and it does not show any significant difference only then i'll stop giving it to Aqeel.

Alivia Mary,
I wish you all the best with your daughter etc. You are all in my prayers too.  :grouphug

Sure hope that Thalgen will be made available soon!

Later
Title: Re: H.B from 6.2 to 12, then 9.4, then 7.2,7.1 NOW?
Post by: AL on October 09, 2008, 06:31:33 AM
Hi everyone,

Just to let u all know that Aqeel next check up is in 5 days time. He had running nose and coughing for a while now! We did gave him cough syrup and antibiotics but until know he stills cough. (coughing usually and often during night time).

I did a post right before writing this, sure hope everyone could check also the topic i wrote on [color=#ff1300]Yisui Shengxue Granules[/color] under Working Towards Cure if 'm not mistaken! Just that i thought some us might miss on it.

Later

I wrote...................It seems that this topic of Yisui Shengxue Granules has been brought up before but until now no one knows actually what is it? how to get it? Esspecially here in malaysia!
Title: Re: H.B from 6.2 to 12, then 9.4, then 7.2, NOW 6.2
Post by: Zaini on October 09, 2008, 11:27:26 AM
Hi AL,

For cough,try a spoon full of honey and a pinch or two of turmeric powder in mild warm water,make him drink it half an hour before sleep or just after he wakes up in the morning.It works wonders for my son.

Zaini.
Title: Re: H.B from 6.2 to 12, then 9.4, then 7.2, NOW 6.2
Post by: nice friend on October 09, 2008, 12:15:31 PM
hi AL ,
here is a link please check it has several herbal recipes to handle cold and flu ...once my doctor adviced me Cnnamon Tea ( Qahwa ) For Cold and flu ... this link has some recipes of it ..

http://www.livingawareness.com/coldandfluRecipes.aspx

i think this one is good one ... coze its similar to my mom's recipe ... she made this tea without Suger or any other sweetener ....

Cook Time: 3 minutes

Ingredients:

1 cinnamon stick
1 cup of boiling water
1 regular or decaffeinated black teabag
erythritol, stevia, or another sweetener, to taste (optional)
Preparation:

1. Place the cinnamon stick in a cup.

2. Add the boiling water and steep covered for 10 minutes.

3. Add the teabag. Steep for one to three minutes.

4. Sweeten to taste, if desired.  

Best Regards
Take Care
Umair
Title: Re: H.B from 6.2 to 12, then 9.4, then 7.2, NOW 6.2
Post by: olivia mary on October 11, 2008, 02:07:00 AM
hi everyone...
Just wanted to say Olivia is doing good since her last tx she gained a pound and grew 1/4 in4 weeks.
She just had another tx on Wed. she did good but she was complaining of back pain. Is this normal after a tx? She looks so healthy I am so happy, on the other hand, I know its because of the tx  :sadyup

I hope everyone is doing well. My love to all :grouphug
kathleen
Title: Re: H.B from 6.2 to 12, then 9.4, then 7.2, NOW 6.2
Post by: Zaini on October 11, 2008, 05:28:27 AM
Hi Kathleen,

I am happy to hear that Olivia is doing fine,i am sorry i am not so sure what can be the cause of her back ache,and yes transfusions can do wonders with child's over all health,but keep track of her ferritin levels if she is transfusing regularly now.

Good luck.

Zaini.
Title: Re: H.B from 6.2 to 12, then 9.4, then 7.2, NOW 6.2
Post by: Sharmin on October 11, 2008, 05:51:37 AM
Kathleen,

I am glad to hear that Olivia is doing well after her transfusions.  As Zaini said, you will need to keep an eye on her iron levels if she is transfusing regularily.  My son also complains of back pain once in a while.  Maybe it is from being in an uncomfortable position, or sitting/lying down for too long during transfusion. 

All the best,

Sharmin
Title: Re: H.B from 6.2 to 12, then 9.4, then 7.2, NOW 6.2
Post by: olivia mary on October 11, 2008, 04:21:45 PM
Thank you guys......
Olivia's ferritin was 510 last month I will find out Monday what heer current ferritin level is. I was also thinking that her back could be hurting due to growing she is getting very tall. She looks so beautiful her lips are so red I will let you know on monday about her ferritin.

Kathleen



'
Title: Last Month HB 8.7 - Now H 8.7
Post by: AL on November 07, 2008, 06:50:28 AM
Hi everyone!

Here is the update on Aqeel al Haady!

Today he went to the hospital for his routine check-up! We were worried as he has catched flu a few days ago and that he had cough for the past few months! (coughing occasionally in a day, often at night). Thank God everything is fine. He is not having asthma etc!

He is now 2 years old weighing is 14.1 kg and his height is 98cm. Sure hope that this is within the normal average weight and height!

TODAY! We did found out that Aqeel hb is as the same as previous month that is 8.7  :whew :yay

Now, i'm sticking to what we are giving him! I'm not sure which is influencing his HB level!

To share with the rest of the members here! On top of his daily folic asid and multivitamin, we are giving Aqeel also
1. wheatgrass - 1 full glass a day (1 sachet for 1 glass)
2. juice that comprises honey+dates+habasstus sauda (1 tablespoon in the morning and 1 at night) = product named Al Qurma  (if you search it it will appear only in Malay wordings)
3. Colostrum = product name Alphd Lipid (Occasionally at night, we mix a little of it in formula)

I dont want to gamble on anything so, i will stick to all those above!

Sure hope that this info will help others too!

Later!

 :grouphug

Title: Re: Last Month HB 8.7 - Today also 8.7 (as at 07/11/2008)
Post by: Zaini on November 07, 2008, 07:39:40 AM
Hi Al,

It's great to hear Aqeel is doing fine,keep updating.

Zaini.
Title: Re: Last Month HB 8.7 - Today also 8.7 (as at 07/11/2008)
Post by: Manal on November 08, 2008, 04:50:46 AM
Al, though dates is an excellent source of minerals especially potasium, Selinium and calcium but it has iron too.

This link will help you know what food consist of
http://www.nal.usda.gov/fnic/foodcomp/search/

manal
Title: Re: Last Month HB 8.7 - Today also 8.7 (as at 07/11/2008)
Post by: AL on November 10, 2008, 12:07:58 AM
Thanks Manal!

But it seems that we cannot escape food with iron.
Title: Last H.B 7.4 (as at 21/11/2008) TODAY?
Post by: AL on December 12, 2008, 12:21:12 AM
Hi everyone,

Just wanna share an update on Aqeel.

During the last appointment 2 weeks back, Aqeel hb was 7.4. At first the doctor told us to stay and get ready for BT. But after discussing among them (3-4 doctors), they decided to put in on hold and to told us to come back in 2 weeks time. The reason was, Aqeel is as active as any kid can be.

Today is his appointment back at the hospital, sure hope that he does not need to be transfused.

For the record, aqeel is now 2 years 2 months old! but till now they (the doctor) have not done any test for him for example ferritin etc.

Please advise me on what to get tested, it seems that i got to ask the doctor the do the test rather than them doing it on their on.

Ahhhh Mannnnnn :huh
Title: Re: Last Month HB 8.7 - Today also 8.7 (as at 07/11/2008)
Post by: Andy Battaglia on December 12, 2008, 12:39:36 AM
How many transfusions has he had so far?
Title: Re: Last Month HB 8.7 - Today also 8.7 (as at 07/11/2008)
Post by: AL on December 12, 2008, 01:16:07 AM
He had 3 BT!

1st = at the age of 12 months (october 2007) = 150ml
2nd = at the age of 19 months (may 2008) = 350ml
3rd = at the age of 22 months (september 2008) = 270ml
Title: Re: Last Month HB 8.7 - Today also 8.7 (as at 07/11/2008)
Post by: Sharmin on December 12, 2008, 01:36:36 AM
Dear Al,

I think that it is a good idea to follow the ferritin levels, but chelation usually does not begin until a patient has been transfused for 12 - 24 months - or until the ferritin reaches 1000.  If your son is going to be transfused regularly then chelation will be required in the future,  for now ferritin can be tested intermittently (every few months).  Because your son has low hg it is important to avoid food high in iron because he is likely to absorb iron.  He should avoid red meat and food enriched with iron.   

He will also need supplements such as L-carnitine, calcium/magnesium, vitamin D, zinc, folic acid, vitamin e, IP6 and others that are listed in the supplements thread. 

Sharmin
Title: Re: Last Month HB 8.7 - Today also 8.7 (as at 07/11/2008)
Post by: AL on December 12, 2008, 01:58:13 AM
Thanks Sharmin!

I will get him checked for his ferritin level for sure! Difinitely!
Title: Today HB 7.1
Post by: AL on December 12, 2008, 03:16:26 AM
Aqeel HB today is 7.1.

The doctor is not sure whether to transfuse or not! Please advise!
Title: Re: Last Month HB 8.7 - Today also 8.7 (as at 07/11/2008)
Post by: Sharmin on December 12, 2008, 04:12:39 AM
Dear Al,

If my son's hg were to be that low I would transfuse for sure - but you son presents more like a thal intermedia than a major so I am having a hard time answering your question. 

I personally don't think that a growing, transfused patient's hg should be allowed to go below 90 and these are my reasons : it puts stress on the bones, it puts stress on the spleen possibly causing it to enlarge, it increases blood volume and therefore puts pressure on the cardiopulmonary system, abnormal retics are produced and hemolysis of these abnormal retics depletes NO stores (NO is necessary to keep blood vessels healthy) etc etc.  For these reasons thalassemia major patients are usually transfused at hg between 90 - 100, but since your son presents more like a thalassemia intermedia than a thalassemia major perhaps the guidelines will be different for you than they would be for a thal major. 

Sharmin
Title: 2 weeks back HB 7.4, TODAY HB 7.1
Post by: AL on December 12, 2008, 05:20:34 AM
Thanks Sharmin!

I just got back from the hospital, after discussing among them (the doctors), they decided to put it on hold yet another time. Aqeel has to revisit the doctor again in 2 weeks time.

Anyway, i'll keep you all updated on his situation/progress.

Later! :rolleyes
Title: Re: Last Month HB 8.7 - Today also 8.7 (as at 07/11/2008)
Post by: Andy Battaglia on December 12, 2008, 03:27:30 PM
Al,

Ultimately, you will have to base the decision to begin regular transfusions somewhat on your own observations of Aqeel 's health. If he is developing normally, is not sickly, has a good energy level and if he is doing well on a day-to-day basis, will be the factors that can guide you. Of course, the doctor's advice will play a huge role in this and if they say he must transfuse, then you should do that, but as long as there is any question, Aqeel will rely on your observations. Please try to be objective about it and what you see over time. If he is maintaining the same level of energy and health, he may be able to continue the pattern of occasional transfusions. I do think that because he is manifesting as an intermedia and not major, that fetal hemoglobin inducers (hydrxoyurea) should be given a fair trial of at least one year, before making any decision on regular transfusions. Also, chelation is generally started after twenty transfusions. This isn't anything to be concerned about yet, but it would be beneficial if he was to be taking IP6 and green tea extract to inhibit the damage iron can do in the body. Establishing good dietary habits is also necessary.

Like all parents of thals, you will have to become the expert on your son's health. You have already shown a great deal of growth as a parent and I am confident that you will be able to make the right decisions based on your own objective observations as time passes.
Title: Re: 2 weeks back HB 7.4, TODAY HB 7.1
Post by: Manal on December 13, 2008, 04:30:02 AM
AL

What is his growth rate? Is he maintaing the same rate?  This is the most important thing that you should always have an assesment for.

Please keep us updated and good luck

manal
Title: Re: 2 weeks back HB 7.4, TODAY HB 7.1
Post by: Zaini on December 13, 2008, 11:40:40 AM
One more thing to consider is bone deformation,please keep an eye on it,if you detect any expansion in facial bones,it would be time to start transfusion.

I don't remember if we ever discussed it,and i don't know what other people think about it,but my point of view is that facial features can play a vital role in a person's confidence level,i recently saw a thal intermedia girl,who was transfused once or twice,she had the bone deformation in facial area and stunted growth,she was 13 years old,but you won't believe if you ever saw her.She was very shy and was practically trying to hide behind her mother,i could only imagine what what she must be going through in her mind.

But again intermedias vary a lot,and as Andy said you'll have to become an expert on your son and be the judge,just try to think that way that what would Aqeel want from you,how would he feel in the future when he gets old,because bone deformation is not much reversible.

Keep us updated.

Zaini.
Title: Re: 2 weeks back HB 7.4, TODAY HB 7.1
Post by: AL on December 15, 2008, 09:43:27 AM
Thanks Andy, Manal & Zaini,

To Dr. Andy  :biggrin
I will surely do my best, after all i can always refer to you all in here!  :biggrin

To Manal
Aqeel weight is slightly reduced from last month. Previously his weight was 14.4kg but now its 14.4kg. As for his height, its 98 cm. (the doctor said that his height is O.K)

To Zaini
I will difinitely take your advice into account. By the way, i've change the picture of aqeel, that is how he looks like at the moment! What say you? heheh  :biggrin

Thanks again everyone, Love u all  :hugfriend

Title: Re: 2 weeks back HB 7.4, TODAY HB 7.1
Post by: Manal on December 15, 2008, 06:01:48 PM
Hi AL

The picture is so nice, may God bless him. I think his weight is also in te normal range for his age. Please  always update us and keep up the good work

manal
Title: 2 weeks back HB 7.1, TODAY HB 6.2
Post by: AL on December 26, 2008, 09:16:57 AM
Hi everyone!

Aqeel is at the hospital at the moment, he's getting his BT for the 4th time. This is the first time ever they are putting in the blood straight not using any machines! And this is the first time ever also that Aqeel seems to be not at ease with the transfusion. He kept asking to open the needle form his hand saying that it hurts.

By the way, His HB was 6.2, weight was 14.5kg and his height was 99cm & he is 2 years and 2 months old!

I'm going back to the hospital in five minutes time, will update you guys later!

Later



Title: Re: 2 weeks back HB 7.4, TODAY HB 7.1
Post by: Zaini on December 26, 2008, 08:46:53 PM
Hi AL,

I know transfusions are hard in the beginning,but as you and Aqeel both get used to them ,they'll be more like a routine,if you decide to transfuse him regularly,and you'll see how well he'll grow and his appetite will increase,good luck with the transfusion.

Zaini.
Title: Re: 2 weeks back HB 7.4, TODAY HB 7.1
Post by: maha on December 27, 2008, 06:20:42 AM
Hi AL
What was the speed at which he was transfused? Children do feel uncomfortable when the rate of flow is fast. His weight is very good and height 99cm WOW!!!!. Your little Aqeel is big Aqeel now. :biggrin
take care
maha
Title: Re: 2 weeks back HB 7.4, TODAY HB 7.1
Post by: mother of little on December 28, 2008, 04:21:40 PM
congratulation may allah bless him.and let me know his latest progress
Title: BT for 4th time
Post by: AL on December 29, 2008, 11:53:26 PM
Hi everyone,

Thank you all for the good wishes for Aqeel!  :hugfriend

Just wanna to update on Aqeel!
It seems that after the BT he drinks a lot and looks like his appetite are not as normal. He eats a little these few days. Besides that, he is as active as usuall.

Maha,
About his BT the other day, about the speed of transfusion, well, roughly its between 3 to 3.5 hours! (390ml)

Later u all
Title: Re: 2 weeks back HB 7.4, TODAY HB 7.1
Post by: Manal on December 30, 2008, 01:08:04 AM
Hello AL

What i know is that in order to calculate the amount of blood transfused, you transfuse 15-20 ml of blood for each kilogram of body weight. So in Aqeel case and knowing that he is 14.5 kg. This means he should transfuse from 217ml to 290ml maximum. So why are you transfusing 390 ml, isn't this a big load on the heart?????????????????????????

manal
Title: Re: 2 weeks back HB 7.4, TODAY HB 7.1
Post by: AL on December 30, 2008, 04:04:05 AM
Ops sorry i meant 290ml!

they gave the blood in a full bag. When the bag is almost finished they stopped it!

Sorry for the confusions!

Title: Update: 2 weeks back HB 7.5, TODAY HB 7.7
Post by: AL on March 16, 2009, 10:02:09 AM
Hi everyone! just wanna to update on Aqeel progress!

Aqeel HB increased a bit, now its 7.7!
2 weeks back it was 7.5 and the doctor told us to visit them again in 2 weeks time (that was a day before yesterday),.

We were thrilled coz this is only the 2nd time his HB in increased! The first time was way back last year in february/march!

We did study this two weeks and try to make sure that whatever we gave him during the 2 weeks maintained!

It seems that recently he eats a lot, he ate cookies/biscuits a lot and we gave him promegranate juice every day!

we have stop giving him wheatgrass as for the past 1 year or so,,,we dont see any specific improvements on him.

Later
Title: Re: 2 weeks back HB 7.5, latest HB 7.7
Post by: Manal on March 18, 2009, 12:15:09 AM
Good luck AL please keep updating, i believe so much i n nutrition and howi t makes a lot of difference

manal
Title: Re: 2 weeks back HB 7.5, latest HB 7.7
Post by: Sharmin on March 18, 2009, 12:17:40 AM
Best of luck Al,

I am happy to hear that his hg is increasing and I hope you see continued progress. 

Best,

Sharmin
Title: Re: 2 weeks back HB 7.5, latest HB 7.7
Post by: nice friend on March 18, 2009, 08:33:19 AM
 :goodluck AL ....

Best Regards
Take Care
Umair
Title: HB 7.7 down to 6.7
Post by: AL on March 24, 2009, 11:51:10 PM
:'(

Hi Everyone!

Just wanna update, Aqeel had fever+flu+cough for like 1 week now, (due to that he does not eat well as before, and i personally believe that his weight is now reduced), to control the fever, we had to give him paracetamol for like every 5 hours.

At one time he does look week so i sent him straight to the hospital. At the hospital the doctor said that his Hg is 6.7 and his fever was 38, the doctor also notice that his throat is infected (that may be the reason why he does not eat well).

After refering with another doctor, he decided that eventhough Aqeel Hg is 6.7, he told us to give another week and gave medecines for the throut etc. He then told us to to make a revisit in 1 week.

We'll see in 1 week time about the status,,,i will difinately update u all on this.

At the moment Aqeel still does not eat well, (infact too little), but his fever is under control!

Later
Title: Re: Latest Update On AQEEL
Post by: Manal on March 24, 2009, 11:57:46 PM
I am sorry to hear this AL, but it will benefit him so much if you can give him fresh juice, it will be easier than food, keep him hydrated and supply him with vitamins that he needs. Also don't insist on giving him the typical meals but frequent snaks during the day will be good too. If he is on antibiotics, yoghurt will be very important for him too

Hope he recovers soon    :getwell :getwell

manal


Title: Re: Latest Update On AQEEL
Post by: nice friend on March 25, 2009, 05:28:25 AM
I m sorry to hear about the condition of Aqeel , i hope that he will b fine and recover soon ...
Wishing him a fast recovery ... :getwell :getwell ...


Best Regards
Take Care
Umair
Title: Re: Latest Update On AQEEL
Post by: Sharmin on March 25, 2009, 05:30:50 AM
I hope that our dear Aqueel feels better very soon. 

Best wishes to the little sweetie,

Sharmin
Title: Re: Latest Update On AQEEL
Post by: Zaini on March 25, 2009, 05:39:33 AM
I hope Aqeel is feeling better by now,AL did you try carao with Aqeel? Because we noticed that it helped in maintaining hb level in fever.

Zaini.
Title: Re: Latest Update On AQEEL
Post by: AL on March 25, 2009, 06:02:58 AM
Thank you All for the wishes!

Zaini,

About carao! We have not tried it coz it seems that the shipment did not arrive! luckily i've made arrangements with Mr. Lloyd that i'll make the payment once i received it!

Planning to go for acupunture later, once aqeel gets better!  There's one center here in Kuala Lumpur that sounded its worth a try!

http://www.thetole.org/

Thanks again to all for the wishes!
Title: Re: Latest Update On AQEEL
Post by: Manal on March 25, 2009, 06:39:40 AM
AL

In what way will Acupuncture help Aqeel???

manal
Title: Re: Latest Update On AQEEL
Post by: AL on March 25, 2009, 06:47:26 AM
Coorect me if i'm wrong, but what they do is that they will focus on the spleen! to reduce it to normal size etc. making the spleen as healthy as it can be. This sure helps isn't it?

In fact, when i told this to a doctor during our visit the other day, she was in a way up to it! BUT, for her its a NO NO for homeopathy!

Later!
Title: Re: Latest Update On AQEEL
Post by: Manal on March 25, 2009, 02:39:58 PM
Hi AL

Actually i have no idea about Acupuncture but commenting on what you said, i can say that the enlargement of Aqeel's spleen is due to a certain cause which is thalassemia, not a malfunction in the spleen itself.. i.e enlargement of spleen is accompanied or an outcome of a certain reason, so how can they control the size without dealing with thal???

Have they ever worked with thal patients before?? And what they are aiming for from reducing the spleen size, is it increasing the HB, sounds like a visious circle to me

But anyway make sure you are in good hands, as i said i am not familiar with Acupuncture but that was my thoughts

Please keep updating

manal
Title: Re: Latest Update On AQEEL
Post by: AL on March 26, 2009, 03:30:54 AM
Hi Manal,

Your concern is also my concern too! Don't worry!  :biggrin thats why i'm still considering it! the thing is, there a number of thalasemic who has been to the centre for the acupuncture!

Have not made up my mind yet! But if, there is no harm in trying and that,,, if it does no harm to other thalassemic,,,i might go for it too!

Later

L
Title: Re: Latest Update On AQEEL
Post by: nice friend on March 26, 2009, 03:59:22 AM
http://www.medicalacupuncture.org/acu_info/articles/aboutacupuncture.html
Quote
ACUPUNCTURE: WHAT IS IT?
Acupuncture is a method of encouraging the body to promote natural healing and to improve functioning. This is done by inserting needles and applying heat or electrical stimulation at very precise acupuncture points.
Hi Manal Sis,
i think they are gona insert needles or poke in his spleen .. not sure , but if it is gona happen like this , then i m also a little concerned about it.....

Alot of good Wishes &
Best REgards For Aqeel

Take Care
Umair
Umair
Title: Re: Latest Update On AQEEL
Post by: Andy Battaglia on March 26, 2009, 04:06:43 AM
Acupuncture needles are not inserted deeply at all. There is no chance an organ would be pierced. I think we should wait and see before speculating on the possible effect of acupuncture in this case. I do think nigella should also be used. Umair's experience using nigella for his spleen and Ambareen's experience using it for hepatitis and the success both had, along with the mountains of research going on into the value of nigella, do suggest we should be recommending this for improving organ function.
Title: Re: Latest Update On AQEEL
Post by: SF on March 26, 2009, 04:15:14 AM
AL,

As Andy recommended, I would try Nigella before trying anything else. I have also started taking Nigella for my HepC. My spleen and liver are also a bit enlarged.. So, I'm hoping to attack a couple of things with this simple seeds of Nigella.

Wishing Aqeel the best!
-SF
Title: Re: Latest Update On AQEEL
Post by: nice friend on March 26, 2009, 04:27:52 AM
Oh yeah , i forgot to mention about Nigella , AL , that is superb idea , my dad gave me nigella and result was decreased size of spleeen ...  i think , you should try give him Nigella ( grinded wil be best as my father gave me grinded as well .. ) for you little one amount will be little as well 1/4 of teaspoon .. .. Best of Luck AL ... I hope that Aqeel would like nigella with Honey :P :food ..

Alot of good wishes and
Best Regards for Aqeel
Take Care
Umair
Title: Re: Latest Update On AQEEL
Post by: SF on March 26, 2009, 04:53:14 AM
Umair,

How do you know your spleen size has decreased? I mean does the doc measure it by touching or have you gotten an ultrasound measuing your spleen before and after taking the Nigella seeds?

Thanks & best regards,
SF
Title: Re: Latest Update On AQEEL
Post by: Sharmin on March 26, 2009, 05:17:07 AM
Andy,

Could acupuncture be helpful for lil A and his antibody issue?  His reactive airway?

Sharmin

Title: Re: Latest Update On AQEEL
Post by: T @ r ! Q on March 26, 2009, 06:15:39 AM
I have heard of another thing Acupressure. In which you apply pressure to pressure points in your palm and feet. Each point represents an organ or body function. And it doesn't sound harmful as it doesn't puncture. I have a book on it in which pressure point map is given and i irregularly try it specially on liver and spleen points. I bet Umair can find reference articles on it and share it with everyone. Umair buddy what ya say!
Title: Re: Latest Update On AQEEL
Post by: Sharmin on March 26, 2009, 06:22:12 AM
Actually Tariq,

We have tried acupressure before - both lil A and I tried it in 2004 for 3 weeks.  It made a big difference in my energy level and it alleviated lil A's reactive airway, almost completely at the time.  The antibody issue did not exist at the time.  Since then we have moved quite a way away from the place we had gotten acupressure at. 

I found the treatment to be very effective, but very painful to endure. 

Sharmin
Title: Re: Latest Update On AQEEL
Post by: T @ r ! Q on March 26, 2009, 06:39:40 AM
Why don't you try doing it yourself. I mean why did you needed to go to the treatment center for that? Because i thought one can try it on himself/herself. Maybe i am wrong about it because i haven't seen any treatment center for Acupressure around here.

I try it whenever i am feeling down or feeling like Hg is dropping and it does appear to help regain strength. I also tried it for increasing height but it didn't work in that case. I have a wooden thick stick with pointed edges all over it (had it made specially for the purpose) and i used to roll it under my palm and feet so that all the points get pressure simultaneously (sort of body maintenance technique) but i haven't done it for long now.

I also keep on pressing points on palm while programming when i get stuck in some coding logic and trying to figure things out  :crackup
Title: Re: Latest Update On AQEEL
Post by: nice friend on March 26, 2009, 06:45:32 AM
Hi Buddies ,
Well , Sharmin has commented on it and i dont know wat more to say soo i m gonna post only quotes and a few links  :
Quote
Definition

Acupressure is a form of touch therapy that utilizes the principles of acupuncture and Chinese medicine. In acupressure, the same points on the body are used as in acupuncture, but are stimulated with finger pressure

instead of with the insertion of needles. Acupressure is used to relieve a variety of symptoms and pain.


Self-treatment
Acupressure is easy to learn, and there are many good books that illustrate the position of acupoints and meridians on the body. It is also very versatile, as it can be done anywhere, and it's a good form of treatment for spouses and partners to give to each other and for parents to perform on children for minor conditions.

While giving self-treatment or performing acupressure on another, a mental attitude of calmness and attention is important, as one person's energy can be used to help another's. Loose, thin clothing is recommended. There are three general techniques for stimulating a pressure point.

Tonifying is meant to strengthen weak chi, and is done by pressing the thumb or finger into an acupoint with a firm, steady pressure, holding it for up to two minutes.
Dispersing is meant to move stagnant or blocked chi, and the finger or thumb is moved in a circular motion or slightly in and out of the point for two minutes.
Calming the chi in a pressure point utilizes the palm to cover the point and gently stroke the area for about two minutes.
There are many pressure points that are easily found and memorized to treat common ailments from headaches to colds.

For headaches, toothaches, sinus problems, and pain in the upper body, the "LI4" point is recommended. It is located in the web between the thumb and index finger, on the back of the hand. Using the thumb and index finger of the other hand, apply a pinching pressure until the point is felt, and hold it for two minutes. Pregnant women should never press this point.
To calm the nerves and stimulate digestion, find the "CV12" point that is four thumb widths above the navel in the center of the abdomen. Calm the point with the palm, using gentle stroking for several minutes.
To stimulate the immune system, find the "TH5" point on the back of the forearm two thumb widths above the wrist. Use a dispersing technique, or circular pressure with the thumb or finger, for two minutes on each arm.
For headaches, sinus congestion, and tension, locate the "GB20" points at the base of the skull in the back of the head, just behind the bones in back of the ears. Disperse these points for two minutes with the fingers or thumbs. Also find the "yintang" point, which is in the middle of the forehead between the eyebrows. Disperse it with gentle pressure for two minutes to clear the mind and to relieve headaches.
— Douglas Dupler

Precautions

Acupressure is a safe technique, but it is not meant to replace professional health care. A physician should always be consulted when there are doubts about medical conditions. If a condition is chronic, a professional should be consulted; purely symptomatic treatment can exacerbate chronic conditions. Acupressure should not be applied to open wounds, or where there is swelling and inflammation. Areas of scar tissue, blisters, boils, rashes, or varicose veins should be avoided. Finally, certain acupressure points should not be stimulated on people with high or low blood pressure and on pregnant women.

Research & General Acceptance

In general, Chinese medicine has been slow to gain acceptance in the West, mainly because it rests on ideas very foreign to the scientific model. For instance, Western scientists have trouble with the idea of chi, the invisible energy of the body, and the idea that pressing on certain points can alleviate certain conditions seems sometimes too simple for scientists to believe.

Western scientists, in trying to account for the action of acupressure, have theorized that chi is actually part of the neuroendocrine system of the body. Celebrated orthopedic surgeon Robert O. Becker, who was twice nominated for the Nobel Prize, wrote a book on the subject called Cross Currents: The Promise of Electromedicine; The Perils of Electropollution. By using precise electrical measuring devices, Becker and his colleagues showed that the body has a complex web of electromagnetic energy, and that traditional acupressure meridians and points contained amounts of energy that non-acupressure points did not.

The mechanisms of acupuncture and acupressure remain difficult to document in terms of the biochemical processes involved; numerous testimonials are the primary evidence backing up the effectiveness of acupressure and acupuncture. However, a body of research is growing that verifies the effectiveness in acupressure and acupuncture techniques in treating many problems and in controlling pain.

There was a few more headin in this article
1) Description Origins
2) Acupressure and Chinese medicine
3) 5min Related Video: Acupressure

for complete article please visit : http://www.answers.com/topic/acupressure

these 2 are also good links to learn about it, must check it ( most important links) :

http://www.acupuncture4pain.com/t_acupressure.asp

http://www.acupressure.com/

@ SF ,
i dont remeber exactly it was done by USG or LFT , i will try to find out my reports ( if those reports are still existing in my any file :grin ) , but i remeber that my fatty belly was shrinked at that time and my shirts turned into Beggy Style like shirts ....  

here's a reason to eexplain its effectiveness over spleen is , hemolysis/red cells break's in spleen and bcoze of that its possiblee that spleen store's alot more iron than other organs and Nigella has also anti-oxidant properties , soo it can work for spleen as well ,,  i think thats why my fatty bely was shrikned that time  ....

Best Regards
Take Care
Umair

Title: Re: Latest Update On AQEEL
Post by: AL on April 17, 2009, 01:49:04 AM
Hi everyone!

2 weeks back after he had his fever, Aqeel Hg was 7.1. Since then we have started giving him a new concentrate wheatgrass + honey and we are giving him also Bee Pollen. The wheatgrass + honey is a new brand which i got during my trip to a fruit farm in Johor. The place is like 5-6 hours drive from my place. The previous wheatgrass given was in powder form. For the benefits of the Bee Pollen please check out http://www.benefitsofbeepollen.com/

Yesterday, we found out that Aqeel Hb was 7.5 and the doctor made another appointment for 8th of May 2009. Alhamdulillah (thank God), we have delay yet another transfusion.

Currently Aqeel is as active as he can be, and i notice that lately he really eats a lot.  :biggrin

Later

Title: Re: Latest Update On AQEEL
Post by: Zaini on April 17, 2009, 04:55:26 AM
AL,

I am glad to hear Aqeel's hb is increasing,keep up the good work  :thumbsup

Zaini.
Title: Re: Latest Update On AQEEL
Post by: Manal on April 17, 2009, 01:48:53 PM
AL

I am really sooooooooo happy , way to go

manal
Title: Re: Latest Update On AQEEL
Post by: Sharmin on April 17, 2009, 02:03:19 PM
I am glad that Aqueel's hg is rising and that he has got a good apetite :)

Sharmin
Title: Re: Latest Update On AQEEL
Post by: nice friend on April 17, 2009, 03:55:58 PM
I m Realy happy for him :) way to go buddy , and best of luck

Umair
Title: Re: Latest Update On AQEEL
Post by: Andy Battaglia on April 18, 2009, 08:17:03 PM
Bee pollen has a good reputation. This is the first time I have heard of it being used by a thal. Please keep us updated and let us know what you observe when he uses bee pollen.
Title: Re: Latest Update On AQEEL
Post by: MomofABabyThalMajor on April 19, 2009, 02:43:42 AM
Hi AL,
I was reading the post's regarding Aqueel. I am happy his hg level is doing good, as my son is also E-Beta thal, just wanted to know from you at what age did Aqeel start on his transfusion and at what intervals you have to give him transfusion? Does he have hg A or only hg E? How old is he now? Any advice will be appreciated. Good Luck and all the best
Title: Re: Latest Update On AQEEL
Post by: AL on April 21, 2009, 03:54:02 AM
Hi everyone!

Thank You for all the well wishes.

To Andy!
I will for sure update on the usage of bee pollen. I never thought that i'll be the first in this group who are trying it. So far, everything looks fine. :wink

To momofABabyThalMajor
My son Aqeel is now 2 and a half years old. He had his first transfusion on his 1st birthday  :wah. Till now he has had 4 BT. The interval between the transfusion are around 3-4 months.
To be frank i dont have any advice in particular, just that! do whatever you can to your capabilities, dont worry about the transfusion should there be any, Take good care of your son and try to make him happy always. Everything will be fine Insya'Allah (Gods willing).  :hugfriend

Take care

Later


Title: Re: Latest Update On AQEEL
Post by: AL on May 08, 2009, 06:35:05 AM
Hi everyone!

Today's latest visit to the hospital found that Aqeels HB is as previous month that is 7.5. The doctor checked and everything looks normal except for the slightly oversize spleen as confirmed during previous checks.

On top of that, he is fine and his weight and height increased. Aqeel (2 years and 7 months old) is now weighing 15.8kg and his height is 104cm.  :biggrin

For sure i'm gonna stick to bee pollen and Wheatgrass+Honey for the time being then. :thumbs

LATER!  :grouphug
Title: Re: Latest Update On AQEEL
Post by: maha on May 08, 2009, 11:05:51 AM
Hi AL
Happy to hear Aqeel is doing good and his hb is holding up. I would love to see his latest pic. Do upload when you have the time.

take care
maha
Title: Re: Latest Update On AQEEL
Post by: Manal on May 08, 2009, 11:25:01 AM
Hello AL

Congratulations , this is really good news. It seems that Aqeei is pretty tall cause usually children are 100cm when they are 4 years. Keep up the good work and keep us informed about the bee pollen

manal
Title: Re: Latest Update On AQEEL
Post by: Zaini on May 08, 2009, 05:31:23 PM
AL,

 :thumbs

Zaini.

Title: Re: Latest Update On AQEEL
Post by: AL on June 08, 2009, 02:58:40 AM
Hi everyone!

Just wanna let u guys know that aqeel is being warded at the hospital  since 3 days back,,,he's having a very high fever (39-40c),,,he has been given drip and also antibiotics.

His HB now is 6.5! He's not eating and drinking well.

 :pray (sure hope he recovers soon)

Later!

Take care everyone  :hugfriend
Title: Re: Latest Update On AQEEL
Post by: nice friend on June 08, 2009, 03:15:13 AM
Hi AL ,
i m sorry to hear abt the condition of cute little boy "Aqeel" .. i hope that he'll recover soon and wish that he recover ASAP ... May God bless him with health (AMEEN) .... Always Praying for him and other thals :) ..

Best Regards
Umair
Title: Re: Latest Update On AQEEL
Post by: AL on June 08, 2009, 03:59:13 AM
Hi AL ,
i m sorry to hear abt the condition of cute little boy "Aqeel" .. i hope that he'll recover soon and wish that he recover ASAP ... May God bless him with health (AMEEN) .... Always Praying for him and other thals :) ..

Best Regards
Umair

My PRAYERS are always for OTHER THALASSEMICs Too! Ameen
Title: Re: Latest Update On AQEEL
Post by: maha on June 08, 2009, 04:12:56 AM
Hi AL
Hasn`t Aqeels fever reduced with IV antibiotics. Once his infection has cleared both his hb and appetite will return to normal, Inshallah.
Wishing Aqeel a speedy recovery

maha
Title: Re: Latest Update On AQEEL
Post by: AL on June 08, 2009, 04:34:07 AM
Hi!

His fever has not reduced! Now its 39.2 C. They said that it would take like 24 hrs to take effect. Should his fever remains, they're considering to change the dosage or change a different kind of antibiotics  :huh

Later!
Title: Re: Latest Update On AQEEL
Post by: Dori on June 08, 2009, 07:13:09 AM
I hope the fever will soon leave him.

Get well soon, sweety.

He & the rest of the family is in my thoughts.

Dore
Title: Re: Latest Update On AQEEL
Post by: Zaini on June 08, 2009, 12:26:56 PM
AL,

I am really sorry to hear about Aqeel's fever,i hope he'll recover really soon, please keep updating us.

Zaini.
Title: Re: Latest Update On AQEEL
Post by: AL on June 11, 2009, 05:05:09 AM
Update on Aqeel!

Today is Day 6 at the hospital! His fever has resided! But he looks pale and weak! His HB is now 5.5!

Currently! waiting for blood for transfusion! The doctor said that in order to get HB between 12 range, they planning to do transfusion twice, today and tomorrow!

Hope for the Best!  :pray

LATER!

Title: Re: Latest Update On AQEEL
Post by: Zaini on June 11, 2009, 07:16:03 AM
Hi AL,

I hope Aqeel will be feeling better in no time,you are doing the right thing by transfusing him,hb of 5.5 is really not good for him,infact i'll suggest you think about putting him on regular transfusions and discuss this with your doctor too,i know the idea seems unthinkable right now,but two of our members Dimple and Kathleen made that decision about their intermedia kids and they are happy with it,with regular transfusions you'll see a postive change in him,in his growth,in his eating habits,and most of all in his immunity,so just think about it.And its just my opinion,implementing it or not is up to you.

Get well soon little Aqeel  :hugfriend

Zaini.
Title: Re: Latest Update On AQEEL
Post by: Dori on June 11, 2009, 09:30:07 AM
Inddeed it's not good to have such hb. You know,  i always get a transfusion with 5.5 ML/L, so having 5.5 dl/gl  :scared

I hope little Aqueel feels better soon!  :hugfriend
Title: Re: Latest Update On AQEEL
Post by: hopefulmommy on June 11, 2009, 02:11:25 PM
Hi Al,

Wish Aqeel speedy recovery.He is in our prayers.
Best wishes
Title: Re: Latest Update On AQEEL
Post by: MomofABabyThalMajor on June 11, 2009, 08:06:15 PM
Hello,
Hoping that Aqeel gets better very fast.
Pls. keep u updated.

Good Luck.
Title: Re: Latest Update On AQEEL
Post by: Andy Battaglia on June 11, 2009, 08:34:15 PM
Al,

It's good to hear things are finally being resolved. Aqeel will feel like a new boy once his Hb is high.
Title: Re: Latest Update On AQEEL
Post by: Manal on June 11, 2009, 11:42:36 PM
Please update us. I hope our little angel a speedy recovery :hugfriend

manal
Title: Re: Latest Update On AQEEL
Post by: Sharmin on June 12, 2009, 06:40:20 AM
Praying for the best for Aqeel. 

Sharmin
Title: Re: Latest Update On AQEEL
Post by: AL on June 12, 2009, 03:35:38 PM
Hi!

Aqeel is now out of the hospital (after exactly 7 days at the hospital). He has had his BT done, to a total of 400 ml.

As what you said Andy, he does look and feel like a new boy, He is so active and he eats and drinks a lot.

It seems that when they did an xray on him, there are some  infections. Currently he is doing fine but he still]s coughing occasionally. I would personally say that ,most probably the infections are due to the fact that he had been coughing for quite some time now (1-2 months).

Sure hope that he stops his coughing though.

Later

Title: Re: Latest Update On AQEEL
Post by: Andy Battaglia on June 12, 2009, 04:04:45 PM
Was he checked for pneumonia and bronchitis?
Title: Re: Latest Update On AQEEL
Post by: Zaini on June 12, 2009, 07:09:12 PM
Glad to hear your little angel is feeling fine, :hugfriend

Zaini.
Title: Re: Latest Update On AQEEL
Post by: AL on June 18, 2009, 12:44:24 AM
Its Bronchopneunomia!  :huh
Title: Re: Latest Update On AQEEL
Post by: Sharmin on June 18, 2009, 01:59:37 AM
Oh dear, I hope that he feels better soon.
Title: Re: Latest Update On AQEEL
Post by: Zaini on June 18, 2009, 08:04:12 AM
AL,

Is he still coughing and having difficulty breathing?
Title: Re: Latest Update On AQEEL
Post by: AL on June 18, 2009, 08:32:15 AM
AL,

Is he still coughing and having difficulty breathing?


Yup! He still coughing, infact, yesterday when i came back from work to fetch him i notice he had slight fever, 37.5C, we gave him paracetamol, and early in the morning around 2a.m, his fever was 38.9. Again we gave him paracetamol (tru anal), and his fever resided after 30 minutes to an hour wait.

I'm at work at the moment, sure hope that he is ok! We sent him to the nursery, and they did not give us a ring should there be anything! Tried to give them a ring but to a failure.

BTW, thinking of giving Aqeel cod liver oil! Anyone has a say on this? Did some reading, it seems that it helps! Appreciate it!

Praying for his cough to go away!

Later

Title: Re: Latest Update On AQEEL
Post by: Zaini on June 18, 2009, 11:57:11 AM
AL,

A little home remedy for his cough,put a spoon of honey and a pinch of turmeric in a cup of mild warm water and give it to him,my son has been through Pneumonia twiceand which ever kind of cough kids have,i have found this remedy really really helpful.

Zaini.
Title: Re: Latest Update On AQEEL
Post by: AL on June 19, 2009, 01:02:48 AM
Thanks Zaini, i might just do that!

Update on Aqeel,

Aqeel complained about ear ache yesterday! He cannot sleep due to that. At first i thought that there might be foreign object inside his ear, we went to see the doctor at midnight yesterday, the doctor said there's nothing in his ear but there's quite bad infection in his mouth. Due to that, it effected his ears.  :(

I really did wonder why when he was admitted at the hospital for 7 days the doctor did not give Aqeel any cough syrup? In fact after the transfusion was made, and fever resided, the doctor said that the cough will go off on its own! They only gave antibiotic for 1 day usage and folic asid! No antibiotics given! And no paracetamol for his fever should he has any later! Now i'm starting not to trust any doctor, Some say like this, some say differently!  ???

Ok back to yesterdays midnight visit to the clinic, the doctor then gave antibiotics, cough syrup, syrup for the flam and paracetamol for fever. He said that, GODS WILLING (Insya'ALLAH), everything would be fine in 3 days time.

Sure Hope So!

Ameen!

Title: Re: Latest Update On AQEEL
Post by: Manal on June 19, 2009, 01:08:22 AM
AL

I wish our little angel a speedy recovery too.

Zaini's remedy is super, i have tried it.

Please never ignore a cough and keep investigating for the reason. will be waiting for your update, take care

manal
Title: Re: Latest Update On AQEEL
Post by: Andy Battaglia on June 19, 2009, 02:14:05 AM
Antibiotics may have cleared up the lung infection some time ago. I don't understand why they were not given earlier. Hopefully, this will now clear out.
Title: Re: Latest Update On AQEEL
Post by: AL on June 19, 2009, 03:03:04 AM
Antibiotics may have cleared up the lung infection some time ago. I don't understand why they were not given earlier. Hopefully, this will now clear out.

Sure Hope sure!

For the record,

Aqeel was admitted last week (from Saturday till Friday). He had high fever continously Day 1 till Day 4. Day 4 at the hospital they put him on drip and later iv antibiotics, Day 5 on Drip and iv antibiotics, Day 6 Transfusion Starts, Day 7 Transfusion and left the hospital.

When i say they did not give antibiotics (What i meant was,, given to us when we left the hospital and to continue at home) Maybe they think that it is enough with the iv antibiotics given. Then gave us a bottle and told us to take it for 1 day 2 times a day.

Sorry for confusing everyone! 
Title: Re: Latest Update On AQEEL
Post by: Dori on June 21, 2009, 03:25:12 PM
just a thought:

First question: How old is Aqeel?

Antibiotics can make a person vit K deficiency. One should add extra green leavy for a week. I don't know how you say it in proper English, but vit K leaves a body pretty fast. Vit K is important for:
    * Blood coagulation
    * Bone metabolism
    * Vascular biology.
(source: wikipedia)


more information: http://lpi.oregonstate.edu/infocenter/vitamins/vitaminK/
Title: Re: Latest Update On AQEEL
Post by: AL on June 22, 2009, 12:44:43 AM
Hi!

 Aqeel is actually 2 years and 8 months old, weighing 16 kg.

By the way, i'm starting to give Aqeel liquid chlorophyll.

Liquid Chlorophyll provides the highest concentration of chlorophyllin from organic alfalfa to specifically support and maintain cellular health. Studies show that natural chlorophyll is absorbed through the gastrointestinal tract and acts as a cellular astringent and antioxidant, as well as stimulates hemoglobin and red blood cell production. Liquid Chlorophyll is indicated for acne, boils, skin ulcerations, burns, eczema, psoriasis, heavy metal and environmental toxicity, and for oral, buccal and dental abscesses. Liquid Chlorophyll is an essential part of any detoxification program and can be applied topically to accelerate the healing of wounds, abrasions and burns. Product ideal for vegans.
I only started this a few days back, cant wait for few months to see any good differences.

Later
Title: Re: Latest Update On AQEEL
Post by: Manal on June 22, 2009, 12:48:28 AM
AL, i think that this is what the wheatgrass is used for. Anyway hope for the best, please update us on the fresh chlorophyl :wink

manal
Title: Re: Latest Update On AQEEL
Post by: AL on June 22, 2009, 01:59:55 AM
AL, i think that this is what the wheatgrass is used for. Anyway hope for the best, please update us on the fresh chlorophyl :wink

manal

 :biggrin
Title: Re: Latest Update On AQEEL
Post by: AL on September 11, 2009, 02:08:36 AM
Hi everyone!  :biggrin

Its been a while since i last update you guys about aqeel. We are now at the hospital for his routine checkup, (for the record the last time we visited the hospital was way back 3 months back when Aqeel had his BT).

I will update you guys once i know his hb level.

Aqeel is now 35 months old (almost 3 years now), his weight is 16.6kg and his height now is 108cm.

Hiope for the best.

Amin.

Later

Title: Re: Latest Update On AQEEL
Post by: AL on September 11, 2009, 03:47:23 AM
Hi!

It seems that Aqeel HB is 6.1, he's going to be admitted soon for BT. The weird thing is, he looks active, i never predicted that his HB was 6.1 at the moment. the only thing that i'm sure is, his appetite is reduce lately.

Later
Title: Re: Latest Update On AQEEL
Post by: AL on September 13, 2009, 12:47:45 AM
hi Everyone,

Yesterday was fastest ever he had his BT done. As if, they were already ready with his blood. How Convenient. We were at the Hospital at 9 in the morning, and we were out by 6.30pm. Usually we had to stay at least for an overnight.

the only thing that i'm worried now is that his spleen is slightly enlarge com[pared to previous check up, that was 3 months back.


later
Title: Re: Latest Update On AQEEL
Post by: Zaini on September 13, 2009, 09:50:08 AM
Hi AL,

Do you check his post transfusion hb? and what did the doc say about enlarged spleen?

Zaini.
Title: Re: Latest Update On AQEEL
Post by: AL on September 14, 2009, 04:07:14 AM
Hi zaini,

For the record for the previous BT and the recent one they did not do check post transfusion hb, infact the doctor just mentioned that the spleen in slightly overlarge but DID NOT SAY MORE!

I would say that the doctor here expect us the ask them instead of them telling us or advice us accordingly.

 :whyme
Title: Re: Latest Update On AQEEL
Post by: Zaini on September 14, 2009, 11:35:48 AM
Keeping track of post transfusion hb will help you keep the record of intervals during his transfusion,and in how much time his hb goes lower,i know there is not a certain pattern for thal intermedia,but with recent transfusions Aqeel seems to be developing a pattern,so keep that in check.

Zaini.
Title: Re: Latest Update On AQEEL
Post by: andreajones021 on September 21, 2009, 03:25:23 PM
Yup! He still coughing, infact, bygone if i came aback from plan to back him i apprehension he had slight fever, 37.5C, we gave him paracetamol, and aboriginal in the morning about 2a.m, his agitation was 38.9. Again we gave him paracetamol (tru anal), and his agitation resided afterwards 30 account to an hour wait.

Title: Re: Latest Update On AQEEL
Post by: Andy Battaglia on September 21, 2009, 03:27:27 PM
andreajones021,

What do diet pills have to do with your rambling post? The link in your "message" has been deleted.
Title: Re: Latest Update On AQEEL
Post by: AL on October 03, 2009, 10:46:50 AM
Hi everyone!

To be frank, i'm starting to be worried.  :( :( :( :-\ :-\
 I'm working in Putrajaya/Malaysia and my son has been to Serdang Hospital for almost 3 years now.

Can i ask everyone in here something if you guys dont mind? Aqeel is now 3 years old (in few days time), (ooh by the way my wife is 17 weeks pregnant), when we went to see the doctor, the doctor told me that ny face look a bit,,,,(i dont remember the word). she said that it may be becouse of excess iron or iron overload. She advise us to do iron chelating the sooner the better.

My question is at what minimal age can we start on those iron chelators? The thing is aqeel has been to the same (general / government)hospital for almost 3 years now but they do not seem to take care of Aqeel thoroughly. What i mean is, everytime we went its gonna be a different doctor,,and every doctor just said that aqeel speel is slightly overlarged. So far i have no details on his iron level, bone density etc...Zero. No annual checks report etc. It seems that every time we went to the hospital, the doctor will check his hb level tahts it. if its low. do bt,,if not its ok then. I'm starting to get worried obout aqeel spleen etc.

can you guys advise me on what to ask and ask to be done, like need to know this figure? this figure? that figure? i will definitely ask the doctor about it and later ask u all on your opinion about it. Please if you dont mind, i hope that i'm not troubling you everyone in this group.

Just that now i dont know who to ask specificly about these things.

p.s.   anyone in here who are from kajang/purajaya/serdang/cheras? please let me knpw whether should i send Aqeel to other hospital perhaps HUKM, University Hospital etc? Perhaps they do have special programs for thalassemic/

THANK YOU.
Title: Re: Latest Update On AQEEL
Post by: Manal on October 03, 2009, 02:44:01 PM
Dear AL

Please read this link and feel free to discuss anything not clear

http://www.thalassemiapatientsandfriends.com/index.php?topic=1762.0

manal
Title: Re: Latest Update On AQEEL
Post by: Nur on October 05, 2009, 04:01:31 AM
Dear Al,

I'm so sorry i did not know of your posts if not for andy telling me to check it out..

I know your worries. Gov doc and hospital 'procedures' are like that in Malaysia. They tell you only if you ask and for us, we need more knowledge to get the best treatment available. And they change docs every 3 months, that makes things worse.

What i can advise you for now, you can go to PPUM, HUKM or Hospital Ampang. they provide that best thalassaemia treatment in the klang valley and surrounding area.

I dont know why there is an obsession for Malaysian doctors to make sure thals remove their spleen even if it is not necessary to do so. Personally i think thru my expirience, what they should take care for is the most basic thing of all and that is proper transfusion (keeping the HB more than 8) and keep the iron deposit low. If these two things were excellently taken care of, Insyaallah, all things will be fine.

Usually there is no minimum age to start chelation.Chelation will start if the ferritin reaches 1000 (roughly about 10 bags of transfused blood)

Hope my info brought any help.


nur[/pre]
Title: Re: Latest Update On AQEEL
Post by: AL on October 05, 2009, 06:38:32 AM
Thanks Andy, Manal and Nur for your reply,

Thanks manal on the manual.

Thanks Andy for getting Nur to read my post and reply

Thanks Nur for the insight and suggestions. Hope that we can be of friends.

Thank you All
Title: Re: Latest Update On AQEEL
Post by: Manal on October 05, 2009, 12:17:52 PM
You are welcomed AL, keep us updated please

manal
Title: Re: Latest Update On AQEEL
Post by: AL on October 06, 2009, 01:12:16 AM
Will do
Title: Re: Latest Update On AQEEL
Post by: AL on December 01, 2009, 02:26:29 AM
Hi everyone,

Sorry for taking some time in updating everyone here on Aqeel, well I've been busy lately thats for sure.

Ok now, he is fine and the last BT done was 2 weeks back. That was when his hb got below 7.

About the suggestion by Nur, we did give it a thorough thought and are still contemplating either to change hospitals or not (as to go for PPUM, HUKM or Ampang Hospital) as those hospitals are quite far from our home (around 30-40 km)(it would take like an hour to reach with the heavy traffic). Just that myself and my wife are working and that to go there once in 3 weeks would be difficult. Furthermore, should somehow aqeel needed immediate / emergency treatment, the current hospital would be the best, as it takes around 10 minutes to reached there from our home.

Just to share with all of you here, recently i was introduced to the person in charge of the pediatric ward. Even the experts are under her wing. I've been told that the ward that aqeel's  attached to are not fully control / manage by them as they have handed over that ward to be taken care by the management of UPM University.  :-\ Thats the reason it seems, is not as organized and managed.

I have also came to know that the Ampang Hospital is the best there is at the moment but they only attend to those aged above 6 years old (if i'm not mistaken as my wife did gave them a ring the other day).

Most likely we've gonna change hospital to HUKM (its far by not that far compared to the others).
Still considering btw.

Nur: Do you know anything on saving the cord blood can be done in public hospitals? Which hospitals? How to go about? i know that serdang hospitals they done di just that

Later

 :grouphug

Title: Re: Latest Update On AQEEL
Post by: AL on January 21, 2010, 01:38:10 AM
Hi everyone,

Its been a while since i last posted here on aqeel update. I've been bz as always, work and personal activities). Well there's not much to update actually, just that he is as usual active as he could be. And that we have already sent him for pre school classes. (Today he is actually 3 years and 3 months old). He does look matured for his age.

I felt that he is a big intelligent young boy now intead of a small baby aqeel :). Well, he is now eager to wake up every morning to go to school. I will for sure post the photos later :).

Btw, aqeel will be soon be an elder brother of a Insya'Allah young and healthy baby girl :). My wife is expecting soon (within the range of 13th march 2010). Please pray for us for a strong and healthy baby girl. Amin.

Okay back to aqeel, his last check up at the hospital, his hb was 7.5 and the doctor mentioned that perhaps he does not need to go for the checks every month, they're planning to set appointment either 1.5 to 2 months.

We're decided to opt for the cord blood bank, and that the only public hospital around that can cater for it is at HUKM. We're getting the representative from the company to explain to us further.

Btw, aqeel takes chlorophyll (if only you guys know the tastes  :mouthshut ) daily now, and its been more than a month now (last time he took it not daily, like 3-4 times aweek). From my observation, he has not been coughing nor having flue lately. I wonder its becoz of taking it. We gonna give another month and see any obvious diference on him.

Later u all
Salam


Title: Re: Latest Update On AQEEL
Post by: Zaini on January 21, 2010, 08:17:02 AM
Hi AL,

Glad to hear Aqeel is doing fine,and congrats in advance for your baby girl  :biggrin .

Zaini.
Title: Re: Latest Update On AQEEL
Post by: Manal on January 23, 2010, 03:23:35 AM
Congratlations AL for the baby :biggrin :biggrin

I remeber that you also were trying the  Bee pollens if i am not mistaken,do yo have any comments on using it??

manal
Title: Re: Latest Update On AQEEL
Post by: AL on January 25, 2010, 12:20:30 AM
Thanks everyone for the wishes, prayed to god for a healthy baby girl.

Manal, Yup (yes) i was the one who gave it a try before, but after 1-2 months, i dont see much difference on aqeel. So i've decided to discontinue it. I still have a lot in hand though, perhaps i'll start using it later, but as for now Aqeel is well off with the chlorophyll, folic asid and multivitamins.

Later
Title: Re: Latest Update On AQEEL & ALEESYA (G6PD Deficient) :(
Post by: AL on March 08, 2010, 03:55:49 PM
Hi everyone, Been a while

Just wanna let u guys know that Aqeel had his BT last week and he's doing fine.

Recently my wife has delivered a baby girl on 04.03.2010 weighing 3.37 kg. My wife is still at the hospital together with the baby named ALEESYA AL AFFIYA (today 08.03.2010) as Aleesya has detected to be G6PD deficient. Now i have to look further on this as i don't have any idea whatsoever about this. Seems like i need to join another group in forums for G6PD deficient.

May i ask all the Guru's around (Dr Andy :) and the rest of the gang) have you guys ever came across cases like i'm facing? Anything whatsoever? Since Aleesya is only 4 days old, and that normally only after 6 months only then we can find out whether Aleesya is thalassemic or not, wondering what if she has the combination of the 2 (G6PD & HBe Beta Thalassemia)? Is there such cases?

Need gather all the information i can in order for us to be well prepared for all circumstances.

Tq, Later

Overview of G6PD Deficiency

G6PD deficiency is an inherited condition in which the body doesn't have enough of the enzyme glucose-6-phosphate dehydrogenase, or G6PD, which helps red blood cells (RBCs) function normally. This deficiency can cause hemolytic anemia, usually after exposure to certain medications, foods, or even infections. See contraindicated substances for a list of things to avoid.

Most people with G6PD deficiency don't have any symptoms, while others develop symptoms of anemia only after RBCs have been destroyed, a condition called hemolysis. In these cases, the symptoms disappear once the cause, or trigger, is removed. In rare cases, G6PD deficiency leads to chronic anemia.

With the right precautions, a child with G6PD deficiency can lead a healthy and active life.

About G6PD Deficiency

G6PD is one of many enzymes that help the body process carbohydrates and turn them into energy. G6PD also protects red blood cells from potentially harmful byproducts that can accumulate when a person takes certain medications or when the body is fighting an infection.

In people with G6PD deficiency, either the RBCs do not make enough G6PD or what is produced cannot properly function. Without enough G6PD to protect them, RBCs can be damaged or destroyed. Hemolytic anemia occurs when the bone marrow (the soft, spongy part of the bone that produces new blood cells) cannot compensate for this destruction by increasing its production of RBCs.

Causes of G6PD Deficiency

G6PD deficiency is passed along in genes from one or both parents to a child. The gene responsible for this deficiency is on the X chromosome.

G6PD deficiency is most common in African-American males. Many African-American females are carriers of G6PD deficiency, meaning they can pass the gene for the deficiency to their children but do not have symptoms; only a few are actually affected by G6PD deficiency.

People of Mediterranean heritage, including Italians, Greeks, Arabs, and Sephardic Jews, also are commonly affected. The severity of G6PD deficiency varies among these groups — it tends to be milder in African-Americans and more severe in people of Mediterranean descent. For a scientific discussion of the different strains of G6PD Deficiency, go here.

Why does G6PD deficiency occur more often in certain groups of people? It is known that Africa and the Mediterranean basin are high-risk areas for the infectious disease malaria. Researchers have found evidence that the parasite that causes this disease does not survive well in G6PD-deficient cells. So they believe that the deficiency may have developed as a protection against malaria.

G6PD Deficiency Symptom Triggers

Kids with G6PD deficiency typically do not show any symptoms of the disorder until their red blood cells are exposed to certain triggers, which can be:

illness, such as bacterial and viral infections
certain painkillers and fever-reducing drugs
certain antibiotics (especially those that have "sulf" in their names)
certain antimalarial drugs (especially those that have "quine" in their names)
Some kids with G6PD deficiency can tolerate the medications in small amounts; others cannot take them at all. Check with your doctor for more specific instructions, as well as a complete list of medications that could pose a problem for a child with G6PD deficiency.

Other substances can be harmful to kids with this condition when consumed — or even touched — such as fava beans and naphthalene (a chemical found in mothballs and moth crystals). Mothballs can be particularly harmful if a child accidentally swallows one, so ANY contact should be avoided.

Symptoms of G6PD Deficiency

A child with G6PD deficiency who is exposed to a medication or infection that triggers the destruction of RBCs may have no symptoms at all. In more serious cases, a child may exhibit symptoms of anemia (also known as a hemolytic crisis), including:

paleness (in darker-skinned children paleness is sometimes best seen in the mouth, especially on the lips or tongue)
extreme tiredness
rapid heartbeat
rapid breathing or shortness of breath
jaundice, or yellowing of the skin and eyes, particularly in newborns
an enlarged spleen
dark, tea-colored urine
Once the trigger is removed or resolved, the symptoms of G6PD deficiency usually disappear fairly quickly, typically within a few weeks.

If symptoms are mild, no medical treatment is usually needed. As the body naturally makes new red blood cells, the anemia will improve. If symptoms are more severe, a child may need to be hospitalized for supportive medical care.

Diagnosing and Treating G6PD Deficiency

In most cases, cases of G6PD deficiency go undiagnosed until a child develops symptoms. If doctors suspect G6PD deficiency, blood tests usually are done to confirm the diagnosis and to rule out other possible causes of the anemia.

If you feel that your child may be at risk because of either a family history or your ethnic background, talk to your doctor about performing a screening with blood tests to check for G6PD deficiency.

Treating the symptoms associated with G6PD deficiency is usually as simple as removing the trigger — that is, treating the illness or infection or stopping the use of a certain drug. However, a child with severe anemia may require treatment in the hospital to receive oxygen, fluids, and, if needed, a transfusion of healthy blood cells. In rare cases, the deficiency can lead to other more serious health problems.

Caring for Your Child

The best way to care for a child with G6PD deficiency is to limit exposure to the triggers of its symptoms. With the proper precautions, G6PD deficiency should not keep your child from living a healthy, active life.

Reviewed by:
Elana Pearl Ben-Joseph, MD
Nemours Center for Children's Health Media
Alfred I. duPont Hospital for Children
Wilmington, DE
Date reviewed: August 2006

http://g6pddeficiency.org/index.php?cmd=overview

Title: Re: Latest Update On AQEEL
Post by: Zaini on March 08, 2010, 04:47:22 PM
Hi AL,

Congratulations on your baby girl,i am sorry to hear she has this problem,i am really sorry i don't know wnything about it,but after reading what you posted,i am hopeful that she'll have an active and healthy life since she has really good parents :) best of luck and prayers and wishes for her  :hugfriend convey my regards to your wife  :hugfriend .

Zaini.
Title: Re: Latest Update On AQEEL
Post by: Manal on March 08, 2010, 11:40:09 PM
AL, congratulations on you baby :biggrin

It is true that usually G6PD is very common in males copared to females who really carry the gene or pass the gene.
I know many friends who have G6PD deficency and doing very fine as long as they keep away from beans (all kinds of beans) and drugs with sulpha which is not a difficult thing to do, it is more of a life style.

The important thing, is that you should test if Aqeel has inherited this because it could be negatively impacting his thal

Manal
Title: Re: Latest Update On AQEEL
Post by: Andy Battaglia on March 09, 2010, 12:06:26 AM
Al,

We have had this topic before. Girls are normally carriers with no symptoms. You can read the previous thread at http://www.thalassemiapatientsandfriends.com/index.php?topic=2768.msg26749#msg26749 My answer is quoted below.

Quote
To answer your other question, G6PD deficiency and beta thalassemia have no relation to each other and neither condition would have an effect on the other. Some basics. If you have a child with a thal major, all of your children will be thal minors (carriers). This may or may not cause some symptoms of anemia, depending on how high the hemoglobin level can be maintained. The odds are that 50% of your male children would have G6PD deficiency and 50% of female children would be unaffected carriers. G6PD deficiency. also known as favism, can have no symptoms or there can be hemolytic episodes caused by ingestion of fava beans and certain drugs. A complete overview can be seen at http://drug.pharmacy.psu.ac.th/wbfile/159254520461.pdf
Most people with G6PD deficiency will have no problems as long as the precautions described on that page are followed.

So, your children would be like hundreds of millions of other people on earth who are thalassemia carriers. There would be no added danger if they carried both thal trait and G6PD.
Title: Re: Latest Update On AQEEL & ALEESYA (G6PD Deficient) :(
Post by: Dori on March 29, 2010, 08:03:29 AM
Hi everyone, Been a while

Just wanna let u guys know that Aqeel had his BT last week and he's doing fine.

Recently my wife has delivered a baby girl on 04.03.2010 weighing 3.37 kg. My wife is still at the hospital together with the baby named ALEESYA AL AFFIYA (today 08.03.2010) as Aleesya has detected to be G6PD deficient. Now i have to look further on this as i don't have any idea whatsoever about this. Seems like i need to join another group in forums for G6PD deficient.

May i ask all the Guru's around (Dr Andy :) and the rest of the gang) have you guys ever came across cases like i'm facing? Anything whatsoever? Since Aleesya is only 4 days old, and that normally only after 6 months only then we can find out whether Aleesya is thalassemic or not, wondering what if she has the combination of the 2 (G6PD & HBe Beta Thalassemia)? Is there such cases?

Need gather all the information i can in order for us to be well prepared for all circumstances.

Tq, Later




Dear Al,

I am very into G6PD deficiency! It's the first enzyme deficiency and mines is the second! I dont know your thalassemia background, but G6PD is often in combination of Thal minor.
G6PD is, for example, a common thing in Italy. It's related to fava beans. When eating that the blood starts to break down and cause hemolysis. There is a whole chapter about G6PD in the book 'Survival of the sickest' written by Sharon  Moalem.

Btw people with G6PD never need blood transfusions. It's interesting that this was detect by your newborn. It's no fun, I know but thal in the family and this.. There is some literature about it.

If there is anything I can do, please let me know.
Title: Re: Latest Update On AQEEL
Post by: AL on March 30, 2010, 03:44:34 AM
Thanks Manal, Zaini, Dr. Andy  :biggrin and Dori,

Hi AL,

Congratulations on your baby girl,,i am hopeful that she'll have an active and healthy life .

Zaini.

Zaini, Thank you so much. I too sure hope that she'll have a healthy and active life.  :hugfriend

AL, congratulations on you baby :biggrin

The important thing, is that you should test if Aqeel has inherited this because it could be negatively impacting his thal

Manal

Manal, I will definitely check about this towards Aqeel. Just to play safe  :hugfriend

Al,

We have had this topic before. Girls are normally carriers with no symptoms. You can read the previous thread at http://www.thalassemiapatientsandfriends.com/index.php?topic=2768.msg26749#msg26749 My answer is quoted below.

To answer your other question, G6PD deficiency and beta thalassemia have no relation to each other and neither condition would have an effect on the other. Some basics. If you have a child with a thal major, all of your children will be thal minors (carriers). This may or may not cause some symptoms of anemia, depending on how high the hemoglobin level can be maintained. The odds are that 50% of your male children would have G6PD deficiency and 50% of female children would be unaffected carriers. G6PD deficiency. also known as favism, can have no symptoms or there can be hemolytic episodes caused by ingestion of fava beans and certain drugs. A complete overview can be seen at http://drug.pharmacy.psu.ac.th/wbfile/159254520461.pdf
Most people with G6PD deficiency will have no problems as long as the precautions described on that page are followed.

So, your children would be like hundreds of millions of other people on earth who are thalassemia carriers. There would be no added danger if they carried both thal trait and G6PD.



Dr. Andy, I really appreciate it, its kinda relieve actually knowing that Aleesya might now have added danger should she carried both thal trait and G6PD. Mind my stupidity, Is there by any chance that Aleesya is major(intermediate) cum G6PD deficient? This is what really worrying me actually.

Dear Al,

Btw people with G6PD never need blood transfusions. It's interesting that this was detect by your newborn. It's no fun, I know but thal in the family and this.. There is some literature about it.

If there is anything I can do, please let me know.

Dori, Thanks Dori, should i have anything else, do mind me in asking later. Btw, from some readings i've made seems like severe case, it goes up until doing blood tranfusion. Still updating myself into more knowledge on these

THANK TOU ALL,,, :hugfriend

Title: Re: Latest Update On AQEEL
Post by: Andy Battaglia on March 30, 2010, 03:52:30 AM
Al,

The G6PD deficiency can't combine with thal minor to be anything more than thal minor. The only way she can be thal major or intermedia is if she carries two beta thal genes.
Title: Re: Latest Update On AQEEL
Post by: Dori on March 30, 2010, 09:47:20 PM
That's sugar! I've never heard of g6pd and blood transfusions. I will ask a woman from Oscar Nederlands. She is doing research about this deficiency and thal minor (at least that's what I thought).
Title: Re: Latest Update On AQEEL
Post by: AL on March 31, 2010, 12:17:33 AM
I will ask a woman from Oscar Nederlands. She is doing research about this deficiency and thal minor (at least that's what I thought).

Thanks Dori, Please update okay!

Thanks again  :hugfriend
Title: Re: Latest Update On AQEEL
Post by: Dori on March 31, 2010, 06:45:57 PM
Al, could you please send me a message about my offer? It's really important when you do so, because the lady took some time off now. She is extremely busy already and will be back in place around 10th April.
Title: Re: Latest Update On AQEEL
Post by: AL on April 01, 2010, 12:21:25 AM
Al, could you please send me a message about my offer? It's really important when you do so, because the lady took some time off now. She is extremely busy already and will be back in place around 10th April.

I've already sent as requested.  :biggrin

Thanks Dori.
Title: Re: Latest Update On AQEEL
Post by: AL on April 13, 2010, 06:43:49 AM
Hi everyone,

Latest update,

Aqeel had fever and cough a few days back, that was 2 days before his routine checkup at the hospital. During the check up he still has fever and cough, since his hb was 6.7, the doctor said that they cannot perform BT and told us to come back straight to the ward for transfusion a few days later after the fever subsided.

Yesterday we went back to the hospital and perform the needed BT (got transfused in total 350 instead of the needed 420). The doctor who checked Aqeel notice that his last transfusion Aqeel was in end of February. This time round, it is sooner than what Aqeel normally go for transfusion (normally he had transfusion very 2-3 months). The doctor then told us that she had to schedule Aqeel for routine check up every 30 days and that Aqeel might have to opt for transfusion on monthly basis. She said that Aqeel's spleen and liver is quite large (4cm and 7cm) due to this they wanted him to maintain HB of above 8. They doctor then reminded us about iron overload and that to take desferal later when needed.

Knowing that Aqeel has to go through desferal later got me worried. I mean for a yound child have to endure all those at an early age (later once he has to).  :wah :wah :wah :wah

Title: Re: Latest Update On AQEEL
Post by: Zaini on April 14, 2010, 05:29:42 PM
Hi Al,

I can understand what is worrying you,but you know there are oral chelators available,so hopefully Aqeel won't have to take needle pricks,Good luck :thumbsup .

Zaini.
Title: Re: Latest Update On AQEEL
Post by: AL on April 15, 2010, 12:22:41 AM
Zaini, Yeah, i know but i'm not sure wheather the hospital has those. Is it possible to buy it? Is it costly?

I wonder
Title: Re: Latest Update On AQEEL
Post by: Zaini on April 17, 2010, 06:42:35 PM
Of coourse its possible to buy Exjade or Asunra,and yes it is a bit costly,I don't know about your currency,but in Pakistani Rupees,a box of 30 tabs of 100 mg Asunra costs 1440 rupees.

Zaini.
Title: Re: Latest Update On AQEEL
Post by: nice friend on April 18, 2010, 03:10:07 AM
Hi AL n Zaini ,
1440 PK.R = 55.38 M.R  (Malasyian Ringgit)
55.38 M.R = 17.26 USD ( U.S Dollar )

so Asunra's price wud b approximately around 55.38 M.R  or 17.26 USD in Malasyia  if Asunra is available there in Malasyia ..

Best Regards
Take Care
Umair
 
Title: Re: Latest Update On AQEEL
Post by: AL on June 15, 2010, 03:43:58 AM
Hi all,  :biggrin

latest on Aqeel (3 years and 8 months old), recently i forgot to give his folic asid and multivitamin for 2 days (unintentionally) but strange enough i see him a bit chubby for the pass few days. As soon as i remembered (that was yesterday), i straight away gave him his folic asid and multivitamin.

For the record, his weight is 19.6kg and his folic asid dosage was 2.5 ml.

Now i'm wondering whether is it becoz of the medicine or something else that made his gain his weight? Today is Tuesday, his next visit to the hospital is in 2 days time (Thursday). Pray for his good health and his H.b as high as he could have. Last month was 7.7

Later  :hugfriend
Title: Re: Latest Update On AQEEL
Post by: Zaini on June 15, 2010, 05:49:55 AM
Hi AL,

I don't think folic acid has something to do with his weight,but folic acid is a B vitamin and B vitamin can sometimes give you stomach ache or loose stools if taken on an empty stomach,was Aqeel having any of those problems when he was taking Folic acid?as this can make a child loose weight.If he is in normal weight range,you shouldn't be worried.

Good luck for the next checkup :goodluck .

Zaini.
Title: Re: Latest Update On AQEEL
Post by: AL on June 15, 2010, 06:22:13 AM
Hi AL,

I don't think folic acid has something to do with his weight,but folic acid is a B vitamin and B vitamin can sometimes give you stomach ache or loose stools if taken on an empty stomach,was Aqeel having any of those problems when he was taking Folic acid?as this can make a child loose weight.If he is in normal weight range,you shouldn't be worried.

Good luck for the next checkup :goodluck .

Zaini.

Aqeel has not been having problems like what you've mentioned. So far his height and weight are within the normal range.

Come to think of it, i'm not worried that he's a bit chubby. I like it actually, feels like he's eating well and doing good.  :biggrin
Title: Re: Latest Update On AQEEL
Post by: AL on June 21, 2010, 03:25:08 AM
Nothing much to udpate really,

Aqeel just got out from the hospital and did a BT (320ml), instead of proposed 400ml. He's doing fine, active as ever.

LATER
Title: Re: Latest Update On AQEEL
Post by: Manal on June 21, 2010, 08:23:11 AM
Happy for you AL, keep it up :wink

manal
Title: Re: Latest Update On AQEEL
Post by: Dori on June 23, 2010, 09:48:47 AM
I am glad to hear it went well. What was his pre transf. hgb?
Title: Re: Latest Update On AQEEL
Post by: AL on June 24, 2010, 04:09:52 AM
I am glad to hear it went well. What was his pre transf. hgb?

His pre transf. hb was 6.6
Title: Re: Latest Update On AQEEL
Post by: Dori on June 28, 2010, 02:02:29 PM
His pre transf. hb was 6.6

In gl/dl or mmol/l ?
Title: Re: Latest Update On AQEEL
Post by: AL on September 06, 2010, 06:09:49 AM
Hi everyone,  :biggrin
In gl/dl or mmol/l ?
, I'm afraid i dont know its in gl/dl or mmol/l?  ???

Sorry, been busy lately, Ok now, aqeel (3 years 11  months) spleen is 7cm, liver 3cm, iron level 6++, last HB 6.7, height 114cm and weight 19.5kg. Due to this he has his 4th BT this year recently that was 2 days back.

Need some advise though, when we went for the monthly check the other day, the doctor who is attending to Aqeel ask for another expert to join in as well. It seems that they are not sure either to maintain their previous call that is to tranfuse when his HB is lower than seven. According to them, they see that Aqeel weight and height is slightly going to stagnent level, they say that it would/would not be stagnent, as they cannot foresee it. ANd that Aqeel face does shows something (dont really know the actual word). After discussion with them, we've decided as suggested by them to get BT not below 7,,but now below 9. Meaning that Aqeel might have to go for BT once a month from now on. Should i stick to below 7,,or chage gradually perhaps below 8 and then below 9? I actually told the doctor that why not we change to below 8 and see but they say it wouldnt help much. They prefer to treat Aqeel as major. Here's his statistics:-

                HB/Weight(kg)/Height(cm)   BT Date
Jan               7.5/18.3/109                      25/2
Feb               6.8/18.7/109                      9/4
Mar                                                    17/6
Apr               6.7/18.9/110                      3/9 350 ml
May               7.7/19.0/112      
Jun               6.7/19.0/113      
Jul               8.4/19.5/113      
Aug/sept       6.7/19.5/114      

Pray that Aleesya (his sister) is not thalassemic. Ameen. Gonna check next month when she is 7 months old.

Later,  :hugfriend



Title: Re: Latest Update On AQEEL
Post by: omega on September 06, 2010, 06:33:28 AM
Hi

My daughter was having the same case as yours and she started on regular monthly BT when she was 5. Maintaining a Hb level above 10 is beneficial to the child.

Cheers.
Title: Re: Latest Update On AQEEL
Post by: Zaini on September 06, 2010, 08:03:53 AM
Hi AL,

I agree with Omega,keeping hb below 7 isn't good for a child's growth.

Zaini.
Title: Re: Latest Update On AQEEL
Post by: Andy Battaglia on September 06, 2010, 03:45:52 PM
Al,

The doctors are correct in saying trying for an Hb of 8 would be useless. Either you stay with the current regimen of transfusing only when below 7, or you commit to regular transfusions and keep the Hb above 9. The in between method was used for years on patients and the results were not good, as patients did not get the real benefit of transfusion and suffered in terms of growth and skeletal deformities. If the child is not developing properly physically at an Hb of 7, transfusions should commence, and the Hb kept above 9 so that physical development can proceed normally. Since the doctors can detect changes in his facial structure (and this is one of the most important measurements in thal intermedia), I would advise to begin regular transfusions. He is at a stage where his bones will expand, causing weakness and malformation, unless more blood is available. Even though he will now need chelation, I am certain you will be much happier with his growth and development once he gets blood regularly.
Title: Re: Latest Update On AQEEL
Post by: AL on September 07, 2010, 07:11:34 AM
Thanks u guys, i sure hope for the very best. He's a strong boy. Gods willing. Will update periodically  :hugfriend
Title: Re: Latest Update On AQEEL
Post by: Zaini on September 07, 2010, 12:14:51 PM
Best of luck,with Aqeel and with Aleesya :goodluck .

Zaini.
Title: Re: Latest Update On AQEEL
Post by: Manal on September 14, 2010, 11:43:41 AM
AL, did you discuss using hydroxyurea with your doctor???

manal
Title: Re: Latest Update On AQEEL
Post by: AL on October 21, 2010, 12:59:23 AM
Hi Manal,

The doctor said that here in Malaysia, every kids must go through the normal iron chelator (not oral). She said that, should there be any problem whatsoever, only then they'll opt the orally active iron chelator.

However, I would still prefer the oral one, just that i dont bare to see Aqeel in any pain.

L

Title: Re: Latest Update On AQEEL
Post by: Syaida Lee on October 21, 2010, 03:21:43 AM
On hydroyurea, I understand that the test to check if it'll work, (xmn etc)  is unavailable in Singapore. (I live at the Southern most of Msia, we see Spore docs due to proximity). I doubt it's available in Malaysia. I've not consulted any hemotologist Msia, but my hemotologist in Spore was a reluctant to administer on Thal Major, she said it works on Intermedia but cautioned on long term side effects. Anyway, she is checking if we can get the test done in Thailand for me.   
Title: Re: Latest Update On AQEEL
Post by: Manal on October 22, 2010, 01:35:25 PM
AL

Hydroxurea is not an iron chelator. It is a fetal HB inducer that can increase HB in some patients and therefore eliminate the need for transfusions

You can read about it in the following links
http://www.thalassemiapatientsandfriends.com/index.php?topic=3694.0;highlight=hydroxurea

http://www.thalassemiapatientsandfriends.com/index.php?topic=3595.0;highlight=hydroxurea

http://www.thalassemiapatientsandfriends.com/index.php?topic=3352.0;highlight=hydroxurea


Syaida Lee
You are right about this test but now doctors tend to try this medication in general because sometimes there are other factors in the ody that makes it work.

Also there was a study done to measure the safety of the drug on long term basis and found that it is safe when used in low doses (up to 20mg/kg)

Also find below an important study about the role of hydroxy in eliminating transfusions in thal major patients done on 49 patients. Please show it to the doctors, hope they get convienced.
 
http://www.ams.ac.ir/AIM/09123/0013.pdf

Title: Re: Latest Update On AQEEL
Post by: AL on October 26, 2010, 03:39:18 AM
Thanks Manal  :hugfriend

I will for sure ask the doctor about this on next visit. Next appointment scheduled on 29.10.2010

Thanks Again

L
Title: Re: Latest Update On AQEEL
Post by: AL on November 03, 2010, 05:46:07 AM
Best of luck,with Aqeel and with Aleesya :goodluck .

Zaini.

 :whew Just got the good news, Aleesya follows her dad, She's Hbe Trait. Daddy's GIRL for sure heheheh :).  :cheer :cheer :yahoo :yahoo :yahoo :yahoo :yay

Thank You to all for the prayers and wishes  :thankyou

Love u all  :love
Title: Re: Latest Update On AQEEL
Post by: Andy Battaglia on November 03, 2010, 05:50:34 AM
 :yaaaaaay
Title: Re: Latest Update On AQEEL
Post by: Zaini on November 06, 2010, 06:37:22 AM
Oh that must be a relief  :biggrin congrats  :hugfriend

Zaini.
Title: Re: Latest Update On AQEEL
Post by: pleasance on November 06, 2010, 10:43:09 AM
Resveratrol is a natural supplement made from red grapes. It is also a hemoglobin inducer that can be used with wheatgrass. Hydroxyurea is a drug that is also a hemoglobin inducer and it can be taken with the other supplements. However, it is a drug, and must be taken under a doctor's supervision.

I am certain the spots were a reaction to the unfiltered blood. Often, an antihistamine like benadryl, is taken along with the transfusion to minimize this type of reaction.







as said above can even a thal major child on regular transfusion regimen also go for Resveratrol & Hydroxyurea  as these are the hb inducers
Title: Re: Latest Update On AQEEL
Post by: Andy Battaglia on November 06, 2010, 05:08:05 PM
Pleasance,

Any patient can take resveratrol. It is a natural supplement and readily found through online supplement companies. Hydroxyurea must be prescribed and taken under a doctor's supervision. However, it is difficult to find doctors familiar enough with the research to approve the use of hydroxyurea on transfusing patients. I would suggest that you talk to the doctor about hydroxyurea. I think in this particular case, it is definitely worth an attempt to see if the transfusion frequency can be reduced.
Title: Re: Latest Update On AQEEL
Post by: joyce on November 14, 2010, 03:34:12 PM
hi al,

hv you started the iron cheator on aqeel?

Does we hve oral iron cheltor here in m'sia? what say the doc on this recently?

joyce
Title: Re: Latest Update On AQEEL
Post by: AL on November 24, 2010, 12:27:05 AM


hv you started the iron cheator on aqeel?

Does we hve oral iron cheltor here in m'sia? what say the doc on this recently?

joyce

Hi Joyce,

Aqeel has not started with any iron chelator yet,, it seems that his iron level is 4++, previously 6++ (did'nt know that it is possible to fluctuate). About the oral chelator here in Malaysia, i did ask the doctor, they said that YES we do have it but only on certain cases will they prescribed it.

Later
Title: Re: Latest Update On AQEEL
Post by: AL on November 24, 2010, 12:52:31 AM
Hi everyone,  :hugfriend

Wish us luck, this coming Friday we're gonna bring Aleesya to the hospital during Aqeels monthly check up. The doctor told us to bring her along in order to see if she's a match for Aqeel.

 :hugfriend :hugfriend

LAter

L

 
Title: Re: Latest Update On AQEEL
Post by: Manal on November 25, 2010, 12:17:44 AM
Best of lick AL, keep updating :biggrin

manal
Title: Re: Latest Update On AQEEL
Post by: AL on November 25, 2010, 12:33:16 AM
Best of lick AL, keep updating :biggrin

manal

Sure hope NOT best of lick!    :biggrin

L
Title: Re: Latest Update On AQEEL
Post by: Manal on November 26, 2010, 01:20:17 PM
Ooops so sorry AL, best of LUCK :rotfl :rotfl
Title: Re: Latest Update On AQEEL
Post by: AL on November 28, 2010, 01:53:10 AM
 :crackup :crackup
Title: Re: Latest Update On AQEEL
Post by: AL on January 05, 2011, 02:27:35 AM
Hi everyone,  :hugfriend

Wish us luck, this coming Friday we're gonna bring Aleesya to the hospital during Aqeels monthly check up. The doctor told us to bring her along in order to see if she's a match for Aqeel.

 :hugfriend :hugfriend

LAter

L

 :( Unfortunately she's NO Match with Aqeel. Only 2/6.

Btw, Aqeel just had his transfusion yesterday, His HB was then 7.4.

 
Title: Re: Latest Update On AQEEL
Post by: Dori on January 05, 2011, 04:16:09 PM
I am very sorry to hear his sister is not a HLA match.
Do you feel comfortable by 7.4 gl/dl?
Title: Re: Latest Update On AQEEL
Post by: AL on March 01, 2011, 02:50:51 AM
I am very sorry to hear his sister is not a HLA match.
Do you feel comfortable by 7.4 gl/dl?

Its ok Dori,,,

i leave it at gods hand. Frankly speaking if you're asking me if i'm comfortable with 7.4, well i do feel comfortable coz i see him as a normal kid without any symptoms whatsoever,,i mean normal kid,,,but the only thing that worries me is that,,his spleen is enlarged etc. I sure hope that he does not need to have BT monthly.

To the rest of the group members  :hugfriend

Well here's an update on Aqeel,,,,we went to the tole (www.thetole.org/) the other day (last saturday to be exact). I told the master (or the chinese doctor) about aqeel and he gave us a compilation of different herbs in 7 packets, for 7 days and were told to see him again after a week. During the visit also he did some acupuncture on Aqeel by sticking those tiny needles (4 of them) at Aqeel's leg for half an hour.

I didn't ask much then, but for sure i'm gonna ask him more during our next visit that is this coming Saturday. There, i see a lot of people there coming from all over malaysia including Sabah (West Malaysia) ,,infact saw some foreigners there too. Btw, that particular clinic was officiated way back in 1993 by former health minister of Malaysia.

We have given Aqeel twice (2 days) the herbs, the herbs has to be boiled and simmer and it tastes bitter (very very bitter). Currently we are wait and see status.

Since Aqeel next appointment to the hospital is on the 6th day of having the herbs this friday, sure hope that there's positive result.  :pray

Will update u guys later when possible

CIAO
Title: Re: Latest Update On AQEEL
Post by: Zaini on March 01, 2011, 04:35:49 AM
Good luck :goodluck i hope the herbs benefit Aqeel.
Title: Re: Latest Update On AQEEL
Post by: love and prayers on March 01, 2011, 06:39:59 PM
Asa,

best of luck!!!
Title: Re: Latest Update On AQEEL
Post by: joyce on March 01, 2011, 11:27:34 PM
Al-
 Don't forget to update Aqeel's progress.
 Really eager to know the result. We pray Aqeel the best!

Title: Re: Latest Update On AQEEL
Post by: love and prayers on March 02, 2011, 06:48:12 PM
joyce how are your kids? haven't gtten any updates...
Title: Re: Latest Update On AQEEL
Post by: joyce on March 03, 2011, 01:09:43 AM
Hi Love..
at the moment.. their condition is just 'okay' :wink--
Thnx for asking ..(^^)!
Title: Re: Latest Update On AQEEL
Post by: AL on May 03, 2011, 06:06:51 AM
Hi zaini and maha

try to look here.http://www.sureco.com.my/madulina.html

this is the exact product i gve to my Joey and Jovy.

it's cost wisely and it is pure honey and live spiruliina.

Hi everyone, its been a while eh?

Anyway i've been busy for sometime now and haven't got the time to update.

Well, there's nothing much to update, as Aqeel went for his routine BT monthly. Just that, we have been given him the same product as Joyce given. Seems that his HB is slightly raised. Because of this, we're sticking with it for another few months.

Btw, not really sure whether i've updated about this,,well last month,(coz for sure i updated it in facebook) prior to his routine BT, aqeel vomitted a few times, for a few days. And his urine was red (really red) for 2 days (i took photos of it and showed the doctor). Because of that we made an early appointment to see the doctor. About the vomitting, the doctor said that it might be coz of (angin/kembung perut)  not sure the real word here,,,,its "air". But to my surprise the doctor has no explaination about the colour red in his urine because they said that after checking his urine sample (TWICE), it is not blood. I showed the photos to the doctor, they were surprised and said that since it is not blood, they told us to go straight to hospital should it happened again.  Anyone here encountered this problem before?

Just an update, as promised. :)

 :hugfriend


Title: Re: Latest Update On AQEEL
Post by: Andy Battaglia on May 04, 2011, 01:40:34 AM
Is it possible that the red urine was related to something he ate like beets?
Title: Re: Latest Update On AQEEL
Post by: AL on May 05, 2011, 08:31:31 AM
Is it possible that the red urine was related to something he ate like beets?

Hi Andy,

Its a NO. We have not given him any beets. No beets for sure 100% SURE
Title: Re: Latest Update On AQEEL
Post by: AL on May 06, 2011, 04:29:03 AM
UPDATE 06.05.2011 12.15hrs.

 :cheer  :veil :stars  :yay

Just got back from the hospital. Can't believe that Aqeels's HB raised to 10.4. I must say that it must be the MADULINA which we tried, recommended by Joyce. Since it was above 9, today no BT is required. The doctor set for the next appointment in 3 weeks time, istead of 1 month like usual. Just that his ferritin is now 700+/-. The last time that we check was way back in September, that was 8 months back. It was was 400+/- way back then. Not sure whether it increased way too fast or not? Any suggestions you guys?

Joyce,
I just bought another 2 bottles yesterday and i got it both for RM103.00 only. Got it as a dealer/agent price. Btw, how much/often do you give daily? I heard that there another member in here who gave twice a day. As for Aqeel, currently, we gave him once daily and it's in the morning together with his multivitamin and folic asid.

:pray
that he would not have to go through BT every month.

Later u all


Title: Re: Latest Update On AQEEL
Post by: nat on May 06, 2011, 09:53:35 AM
 :flowers Great for you!  :cheer

Definitely gonna try this one...I hope my doc will approve  :smileblue
Title: Re: Latest Update On AQEEL
Post by: Manal on May 06, 2011, 04:27:17 PM
Hi AL
I have posted in another link that I have ordered madulina online, but it seemed it was lost :mad and i am very very interested in trying it with my son.

Could you please -if possible- send my a contact of the Agent or a reliable good company that can ship it to me, as you know I live in Egypt .
Or even I can send you the money and the shippment fees and you send it to me

Please let me know

Manal
Title: Re: Latest Update On AQEEL
Post by: AL on May 09, 2011, 12:40:00 AM


Could you please -if possible- send my a contact of the Agent or a reliable good company that can ship it to me, as you know I live in Egypt .
Or even I can send you the money and the shippment fees and you send it to me

Please let me know

Manal

Hi Manal,

I will contact the company where i got it from,,not sure whether they do post it overseas. Dont worry, i will liase with them and see how it goes. Should it be difficult for them, i will do it for you personally :hugfriend (BTW, not sure about the posting fess from Malaysia To Egypt).

Just that i will be busy for these few weeks coz my younger brother is getting married soon on the 14&15th May 2011. I would say by end of May i will not as busy as for the wedding etc.

Will let you know as soon as i can (perhaps i'm message you personally).

Later



Title: Re: Latest Update On AQEEL
Post by: Manal on May 09, 2011, 12:44:26 AM
AL
Many many thanks for your kind reply, I really appreciate that sooooo much :hugfriend. I will be waiting for their reply.
Congratulations for the wedding, hope your brother all the best :biggrin
Manal
Title: Re: Latest Update On AQEEL
Post by: shaziya on May 10, 2011, 05:01:33 AM
HI AL.
Glad to hear that Aqeels HB has increased. hope he is fine now. guess u must be busy with ur brothers wedding.. i just read that u had  started a treatment for Aqeel at the TOLE. what happened? r u still going on with it or did u stop? pls i would really like to know the result. bcoz 2 years ago we also got to know abt the TOLE and went to them. but they said that it is a long procedure and have to stay there for some time if we r doing the treatment. since we were not able to stay there for so many days we did not try the treatment.
 we also saw so many people getting the acupuncture treatment done. and according to the master there he sd he has done it on thals. i would really appreciate it if u could tell me.
thanks
shaziya
Title: Re: Latest Update On AQEEL
Post by: AL on May 11, 2011, 04:10:35 AM
HI AL.
i just read that u had  started a treatment for Aqeel at the TOLE. what happened? r u still going on with it or did u stop? pls i would really like to know the result. bcoz 2 years ago we also got to know abt the TOLE and went to them. but they said that it is a long procedure and have to stay there for some time if we r doing the treatment. since we were not able to stay there for so many days we did not try the treatment.
 we also saw so many people getting the acupuncture treatment done. and according to the master there he sd he has done it on thals. i would really appreciate it if u could tell me.
thanks
shaziya

Well, we did go there once, the procedure does not take that much time,,roughly its about 30-45 minutes,,thats it. We did not further becoz Aqeel did not like the taste of the herbs given (seriously even myself too), and to be frank, its quite expensive for us. If i can recall correctly, it costs us rm4++ for the treatment and was told to visit then every week. After discussing with my wife and thinking of i need to spend like almost 2k,,it is just unaffordable. Another thing is, they said that they do thalassemia, the thing is i did not know personally of anybody who has cured or something like that.

AL
Many many thanks for your kind reply, I really appreciate that sooooo much :hugfriend. I will be waiting for their reply.
Congratulations for the wedding, hope your brother all the best :biggrin
Manal

Thanks bro, will update you about that later.
Title: Re: Latest Update On AQEEL
Post by: shaziya on May 12, 2011, 04:49:13 AM
HI AL
thank u so much for replying.
shaziya
Title: Re: Latest Update On AQEEL
Post by: AL on May 30, 2011, 03:33:33 AM
HB 7.1  :-\
Title: Re: Latest Update On AQEEL
Post by: AL on June 28, 2011, 06:46:16 AM
An Update,

This month is the worst month ever, Aqeel had fever two times in a month (early of this month and now currently have fever with temperature 39 degrees. Adding salt to the wound, his sister Aleesya also had fever/cough/flu and only recently recovered.

Praying for fast recovery  :pray Insya'ALLAH
Title: Re: Latest Update On AQEEL
Post by: Dori on June 28, 2011, 08:30:35 AM
I wish Aqeel speedy recovery.
Title: Re: Latest Update On AQEEL
Post by: Manal on July 09, 2011, 09:53:31 AM
Hope the kids are fine now AL
Manal
Title: Re: Latest Update On AQEEL
Post by: tanzim on August 07, 2011, 07:59:05 PM
Hi  Friends............
I want to collect Madulina & wheat grass (juice/tablet) for my son. Can anybody help me?
Title: Re: Latest Update On AQEEL
Post by: AL on October 31, 2011, 01:28:16 AM
Hi you all

Been a while since i posted in here (really miss all of you here), well i've been busy with work etc.

Ok now, there's nothing much to update really, Aqeel is still having his BT on monthly basis. He is now a 22.8 kg 5 years old boy. :). Just had his 5th birthday on 21st October the other day (thank god he does not have to celebrate his 5th birthday at the hospital like the one he had on his 1st birthday).

Come to think of it, it has been almost 5 years now that i've joined this family. :cheer :yahoo :clap

Currently Aqeel has 2 appointment at the hospital. One for the BT and the other is his dental appointment. Seems like he has problem cavities, seems like he 2-3 cavities and that they're are having problem in filling it. One of it, has been fill 3 times and it still came off. And his gum are swollen and seems like his wisdom ttoth are on the way (the doctor were amaze at his age it seems to developed, and the doctor mentioned that surely it hurts a lot)

Just wondering if any others facing tooth problem like Aqeel? Is it common for thalasemic patients?

OK got to go now, will definitely keep it touch (just dont know when) if time permits  :huh

Later U All.


Assalamualaikum
Title: Re: Latest Update On AQEEL
Post by: Andy Battaglia on October 31, 2011, 01:46:04 AM
Hi Al,

It's good to hear that Aqeel is doing well. You seem much more relaxed these days.  :biggrin  I would suggest that he take a vitamin C supplement of 50-100 mg daily. He can't take a lot of C but he can take small doses like this and this may help with the gum problems, which are often a sign of vitamin C deficiency, one of the most common deficiencies in thals.
Title: Re: Latest Update On AQEEL
Post by: AL on October 31, 2011, 02:52:08 AM
Hi Al,

It's good to hear that Aqeel is doing well. You seem much more relaxed these days.  :biggrin  I would suggest that he take a vitamin C supplement of 50-100 mg daily. He can't take a lot of C but he can take small doses like this and this may help with the gum problems, which are often a sign of vitamin C deficiency, one of the most common deficiencies in thals.

 :hugfriend thanks Dr. Andy (heheheh) , dare not say that i'm more relaxed these days, just that its now a routine monthly transfusion and busy with work etc. Not to mention, we have Aleesya now. Both of them really make us hard to control (knowing kids at their age)  :biggrin

I didn't know its a common deficiencies in thals, will for sure get some vitamin supplement later (small dosage as recommended).

Thanks Doc. :)
Title: Re: Latest Update On AQEEL
Post by: Dori on December 03, 2011, 10:39:08 AM
Interesting, gum problems and vit c deficiency.
Happy belated birthday to your son Aqueel.
Although life may not be relaxing, i do hope you have some sort of routine now (also regarding transfusions) and you can also relax a little bit each day. Five years part of the family. I just thought today how blessed I am to have met people who experience the same.
Title: Re: Latest Update On AQEEL
Post by: joyce on December 30, 2011, 07:27:20 AM
Happy New Year all esp to Al & Aqeel!!

First, Im very sorry for late reply, actly last March my 1st son also diagnosed as having thal major, so just few months when i still tried my best to accept his younger brother's condition, My oldest son also have the very same disease. It really broke my heart. Im so lost that I do nothing except doing my daily routine. I even didn't visit this site for very loong time. & now im back. verry sorry to all.

Second- about the MADULINA... I stopped it loong time ago when my 1st son diagnosed as having thal major because his HB didn't raised after few months I've  gave it to him. I do posted it somewhere here about the MADULINA. 

Third- I want to wish HAPPY BIRTHDAY to Aqeel!!

 :wink :wink :wink :wink :wink :wink :wink :wink :wink :wink :wink :wink :wink :wink :wink :wink :wink :wink :wink :wink :wink :wink :wink :wink :wink :wink
Title: Re: Latest Update On AQEEL
Post by: AL on May 04, 2012, 02:24:03 AM
:) been a while,

Not much of a difference really, Aqeel is on monthly transfusion, have not yet started with the iron chelators. He is now a 6 year old kid (time surely flies) who goes to a kindergarten and slowly learning Mandarin. Planning to send him to a Chinese Primary school next year. I've already registered him at the school and now waiting for their acceptance.

We are now considering of taking him to another hospital as we came to know (in fact we know this last year) that there is no specialist on Thalassemia etc at the hospital. We might end up sending him to a hospital which is 30 kilometers away and got to go through a hell of a traffic. Still contemplating tough :)

His youger sister is now 2 and a half yesr old, and seems that the do quarrel a lot ;) and Aqeel mostly had to give in.

I will update again soon.

Later u guys

 :hugfriend :hugfriend






Title: Re: Latest Update On AQEEL
Post by: mummy_timmy on May 04, 2012, 05:14:38 AM
Salam AL,

I'm in touch with your wife thru FB.

Which hospital do you plan to go?PPUM or HUKM?

My son currently received his treatment at PPUM and feel free to asked me if you need to know more about PPUM Thalas Clinic.

salam and thank you
Title: Re: Latest Update On AQEEL
Post by: AL on June 05, 2012, 09:23:57 AM
Salam AL,

I'm in touch with your wife thru FB.

Which hospital do you plan to go?PPUM or HUKM?

My son currently received his treatment at PPUM and feel free to asked me if you need to know more about PPUM Thalas Clinic.

salam and thank you

Please add me in FB too :)
Title: Re: Latest Update On AQEEL
Post by: AL on November 10, 2012, 10:57:20 AM
UPDATE!

Aqeel has finished his pre school and will be starting primary school next year. He now 24kg in weight and his height is 124cm (roughly)

His iron level 2 months back were 1700 and currently using exjade. We were advice to give him 4 tablet per day equivalent of 125mg deferasirox times 4 = 500mg

Yesterday during the routine monthly check up, we were told that his iron shoot up to 4+++ this is after using exjade daily without a miss for more than 2 months.

The doctor took again his blood to recheck the iron level and were told to come back to the hospital in 3 weeks (normally its 4 weeks)

My Questions is, is this normal? or perhaps the dosage were'nt right. We are now worried that maybe just maybe it is not suitable for him coz it is not effective. This has raise another question, do you guys know any cases where it is not effective to certain patient?

Looking forward to hearing from all the senior members here.

Thank You

For the record, the reason why i'm not active as before is that i am currently a fulltime student taking up Msc Management Psychology. Since then, i only open my computer for my assignments journals searching etc. :)
Title: Re: Latest Update On AQEEL
Post by: Andy Battaglia on November 10, 2012, 03:22:44 PM
The suggested dose for Exjade is 30 mg/kg body weight. At 24 kg, Aqeel should be on at least 720 mg daily. 750 would be an acceptable dose. So, his dose is too low for his weight and should be increased. We have also found that if the dose is split into two and taken half in the morning and half later in the day, that it is more effective at reducing the iron load, as this gives a true 24 hour chelation period, that can't be had through once per day dosing. The world famous thal center at Oakland Children's Hospital is now also recommending this split dose method that was developed at thalpal. It works.
Title: Re: Latest Update On AQEEL
Post by: Pratik on November 10, 2012, 04:40:03 PM
We have also found that if the dose is split into two and taken half in the morning and half later in the day, that it is more effective at reducing the iron load, as this gives a true 24 hour chelation period, that can't be had through once per day dosing. The world famous thal center at Oakland Children's Hospital is now also recommending this split dose method that was developed at thalpal. It works.
I very much second that. My speedy reduction in FE couldn't be possible without split dose! Am taking Asunra too and taking the proper increased dosage and splitting the dose definitely helps. It may also have happened in reports that the iron shown to be high was because of the free iron that has to be chelated was in blood steam, might be a good sign eventually, but we can't say. The dose is low which should definitely be increased to as to what Andy recommended.

-P.
Title: Re: Latest Update On AQEEL
Post by: AL on November 11, 2012, 01:50:07 AM
Thank You Guys,

What do you think? Should i go to the hospital and ask them immediately or just wait for the next appointment that is in 3 weeks time?

Thanks Again
Title: Re: Latest Update On AQEEL
Post by: AL on December 10, 2012, 06:32:46 AM
Update,

Aqeel's iron level dropped from 4+++ to 2+++. Dosage has been increased to 5 tablets per day, instead of 4.

Later :hugfriend
Title: Re: Latest Update On AQEEL
Post by: Pratik on December 10, 2012, 06:43:36 AM
Update,

Aqeel's iron level dropped from 4+++ to 2+++. Dosage has been increased to 5 tablets per day, instead of 4.

Later :hugfriend
Congratulations!
Title: Re: Latest Update On AQEEL
Post by: Bostonian_04 on December 11, 2012, 09:10:11 PM
Al,
in my opinion, one reaading of 4+++ may not be the true ferritin result if Aqeel's ferritin was hovering around 1700 ish before. if you get 2 or more consecutive reading of similar values then it is probably real. Many times fever, infection etc shot up ferritin values which will come down to previous level after the infection/fever has subsided.
We also do split dose for our 6 Year old. This works very well and has much much lower side effects like nausea, stomach pain etc. Good Luck !
Title: Re: Latest Update On AQEEL
Post by: AL on December 16, 2012, 05:40:14 AM
Al,
in my opinion, one reaading of 4+++ may not be the true ferritin result if Aqeel's ferritin was hovering around 1700 ish before. if you get 2 or more consecutive reading of similar values then it is probably real. Many times fever, infection etc shot up ferritin values which will come down to previous level after the infection/fever has subsided.
We also do split dose for our 6 Year old. This works very well and has much much lower side effects like nausea, stomach pain etc. Good Luck !

Will do

They are now currently checking the level frequently. And YES i do split the dose as recommended. So Far So GOOD  :wink

 :hugfriend :hugfriend

will update later
Title: Re: Latest Update On AQEEL
Post by: AL on December 27, 2012, 06:34:51 AM
Hi Everyone  :hugfriend

I'm currently at the hospital taking care of Aqeel for BT.

21/06/2012 Ferritin 1767,  Hb/TWC/Plt = 7.9/9.2/169 weight=23.9kg, height=123cm

26/07/2012 Hb/TWC/Plt = 8.9/9.6/184 weight 24.2kg, height=124.4cm

21/08/2012 Started Exjade with 4tablets of 125 each

30/08/2012 Hb/TWC/Plt = 8.5/10.0/182, weight=24.7kg, height=124

04/10/2012 Hb/TWC/Plt = 7.9/6.2/151, weight=25.1kg, height=126cm

Started Spliting the dose

08/10/2012 Ferritin 2814,                                         weight 24.8kg

29/11/2012 Ferritin 3330,  Hb/TWC/Plt = 10.1/9.9/297, weight 25.7kg

Increased dosage to 5 tablets of 125 each

27/12/2012 Ferritin ? Hb/TWC/Plt =6.7/2.9/39,  weight 25.4kg,

Doctor said that aqeel might me admitted to the ward as his platelet is low.

Would appreciate it if supreme members, senior members, junior members and active members to advice me on the findings given above.

Thank You  :hugfriend
Title: Re: Latest Update On AQEEL
Post by: AL on March 04, 2014, 07:04:25 AM
Hi, been a while since i last posted here

FYI Aqeel is doing fine. he is now 8 years old and in Standard 2 (primary 2). His on monthly transfusion and on exjade. His ferritin is at 3+++. Nothing much to update really just that he's doing okay and still on monthly transfusion. Alhamdulillah

Will upload a recent photo of him later

 :biggrin

Title: Latest Update On AQEEL 29.01.2016
Post by: AL on January 29, 2016, 09:16:30 AM
Hi,

 :biggrin

Just to update on Aqeel. He is now in standard 4 (coming to ten years old). I initially sent him to a chinese school from standrd 1 till 3. But middle of last year i transfered him to a non chinese school but i still send him to his chinese tuition classes. Seems like he cannot cope much on the homeworks as it was all given in chinese and i decided that Aqeel enjoy his life as a kid. Dont want to much stress him out on it. ;)

He recently was awarded the iron Hero from the hospital as his iron was the most reduced among all the kids. his ferritin is now 1+++.

Aqeel was warded for 13 days few weeks back as hes having mycoplasma and denggue that effected his lungs. He is now still coughing though. Yesterday was his monthly BT, and he was given antibiotics for another 5 days.

BTW, My wife is expecting our third child. Please pray for us that the baby is just a minor like my second child. My daughter is a 6 year old active kid having G6PD. So far she have not encountered anything difficulties of breathing etc.

Well thats about it really. Will update again later. :) (one of my new year resolutions is to be active back in this group) huhu.

 :biggrin

Title: Re: Latest Update On AQEEL
Post by: Dori on February 16, 2016, 10:56:58 AM
Thank you for the update.
If I am correct you can do a test during the pregnancy to see if the child has thalassemia  or not.
All the best to Aqeel and your family!
Title: Re: Latest Update On AQEEL
Post by: Sharmin on February 16, 2016, 03:33:50 PM
AL,

Thank you for the update.  Glad to know that Aqeel is doing well. Sending best wishes for your wife and hoping that your third child will be thal minor or have no thal at all.

Best,

Sharmin
Title: Re: Latest Update On AQEEL
Post by: BabyRiya on August 13, 2016, 12:19:06 AM
Hello
May I know after how many transfusions , spleen increases.  If one starts transfusing for a year or so , will the bone marrow stop producing hb and get transfusion dependent?
Title: Re: Latest Update On AQEEL
Post by: Dori on August 13, 2016, 10:58:46 AM
Hello
May I know after how many transfusions , spleen increases.  If one starts transfusing for a year or so , will the bone marrow stop producing hb and get transfusion dependent?

No, the bone marrow will not stop producing red blood cells. But the bone marrow does  not hsve to work crazy hard to try to get hb up. Transfusions bring a little bit of peace.
Title: Re: Latest Update On AQEEL
Post by: BabyRiya on August 14, 2016, 04:18:37 AM
Thank you for your reply! So basically if my baby keep hb level of at least 6.5 without transfusion and we start regular transfusion for a yer or so and then stop, the bone marrow should at least keep the hb leve of 6.5 not less , right?
Title: Re: Latest Update On AQEEL
Post by: Dori on August 15, 2016, 06:35:17 PM
No, I do not think it would like that. A hb is not precize stable. You should see and watch, I think. Do you talk about 6,5 gl/dl? Why so low? Where do you live?

Hopefully Andy will see this post too.
Title: Re: Latest Update On AQEEL
Post by: BabyRiya on August 16, 2016, 12:58:20 AM
I live in USA.  We have seen hb fluctuate between as high as 8.6 and as low as 6.5. We are monitoring.  And in bothe the scenarios since last 4 months we have transfused her as soon as it drops below 7.  She is Thal intermedia and we came to know about this during annual check up.  I went to chop philly and they also said the same to constantly monitor the hb level and decide on next steps.  We transfused when she was 13 months old and then again at 16 months old.  It's been a week now and I will check the number after two weeks. 
My question was related to be on a regular transfusion.  She has some adult hemoglobin like 34 % and she beta + +.  I was thinking if we regularly transfuse her, will the bonemarrow get used to the outside blood and stop producing the current hb even if it's low. 

I am not sure if Thal intermedia major or minor makes any difference.  There should be just two caregoroies. One need regular blood transfusions the other not. 
Praying some day the medicine will be available for kids after clinical trial so that we can avoid the transfusions.  Very difficult to find Iv for a one year old.
Title: Re: Latest Update On AQEEL
Post by: Andy Battaglia on August 19, 2016, 03:03:15 AM
If the Hb is kept below 9, bone marrow activity will continue. The higher the Hb is kept through transfusion, the less your bone marrow will work. The the goal in transfusing thal majors is exactly that, as their bone marrow works and produces nothing of value. If you are trying to minimize transfusions in an intermedia, you want to keep the Hb below 9. In this case, hydroxyurea and wheatgrass may be of significant value in raising Hb without transfusing.
Title: Re: Latest Update On AQEEL
Post by: BabyRiya on August 20, 2016, 02:58:17 AM
Thanks Andy.  That was precisely my question. I want to transfuse so that it stays above 8 and at the same time not transfuse chronically so that bone marrow does not produce anything.  Let's see. Will draw next week which is after 3 weeks of transfusion
Title: Re: Latest Update On AQEEL
Post by: Lokkhi maa on August 20, 2016, 06:38:37 AM

hydroxyurea and wheatgrass may be of significant value in raising Hb without transfusing.

What the dose or how hydroxyurea and wheatgrass should be take for raising Hb without transfusing.My baby is now 3 yrs old and take transfusion after every 5 weeks...

Please advice Andy..
Title: Re: Latest Update On AQEEL
Post by: Andy Battaglia on August 20, 2016, 10:39:33 PM
The dose of hydroxyurea is determined by the doctor. It can only be taken under a doctor's supervision. The typical dose used in thal is 10-20 mg/kg. The dose of wheatgrass is determined by what form the wehatgrass is in. If it's a packaged product, it will have dosing information on the label.
Title: Re: Latest Update On AQEEL / AAMARA
Post by: AL on July 07, 2017, 03:09:46 AM
Hi Everyone, :hugfriend  :hugfriend :hugfriend

Aqeel is now 11 years old this year, and the eldest of 3. Yesterday was his BT day. Dr said that his spleen size is 4cm. liver 1cm. Pre Transfusion HB 8.3.

Later, I will try to give him MADULINA as a lab test has been done by one of our members here and were found to be safe (comprises of Spirulina, honey etc) as i was told that it may have an effect in increasing his HB. Though, to some others it may not. As for me, i'm willing to try it for Aqeel & Aamara sake.

Btw, my youngest daughter Aamara is also as same as Aqeel (Thalasemic) she is now a one year old girl. Did ask the Doctor to do do the electrophoresis test. Waiting for the result. Planning soon to find out if the cord blood from her sister matches should we need to opt for BMT. If possible i dont want my daughter to go through what Aqeel went trough all these while. Cant imagine a little girl has to go be poke every now and then.

FYI, Here in Malaysia, the government Hospitals does not do Unrelated Donor for BMT, wonder which hospitals does it? Anyone here in Malaysia knows?. The fees surely gonna be expensive but he will try to work on it.

 :pray :pray Gene therapy :pray :pray
 :pray :pray Luspatercept :pray :pray  

Later ya

love u all  :hugfriend :hugfriend :hugfriend