Thalassemia Patients and Friends

Discussion Forums => Iron Chelation Corner => Topic started by: Andy Battaglia on July 12, 2008, 04:34:01 AM

Title: A Trial of Oral Nifedipine for the Treatment of Iron Overload Now Recruitng
Post by: Andy Battaglia on July 12, 2008, 04:34:01 AM

A trial of a new oral drug to remove iron in iron overloaded patients is now recruiting patients. This trial will take place at

National Institutes of Health Clinical Center, 9000 Rockville Pike         
         Bethesda, Maryland, United States, 20892

http://clinicaltrials.gov/ct2/show/NCT00712738?rcv_s=06%2F27%2F2008&count=1000

Quote

Please refer to this study by its ClinicalTrials.gov identifier: NCT00712738

Contacts
Contact: Patient Recruitment and Public Liaison Office        (800) 411-1222        prpl@mail.cc.nih.gov   
Contact: TTY        1-866-411-1010   

Based upon recently published data in a rodent model, the purpose of this study is to determine if nifedipine will increase iron excretion in the urine among humans with increased levels of iron. Volunteers will be given a single oral dose (20mg) of nifedipine. Iron level in collections of urine will be measured and compared before and after nifedipine to determine if there is an associated increase in urinary iron excretion.

This appears to be a preliminary trial to see if there is any affect in humans. The trial will consist of a one-time dose of nifedipine. Interested patients in the eastern US who meet the eligibility criteria should consider participating in this trial. The results of this trial will surely lead to further trials if they show an added excretion of iron after this dose.

Title: Re: A Trial of Oral Nifedipine for the Treatment of Iron Overload Now Recruitng
Post by: §ãJ¡Ð ساجد on July 12, 2008, 05:23:23 AM

Awesome! more competition for Novartis.
Prices should go down now :biggrin

Let's hope for the best.

:pray