Thalassemia Patients and Friends
Discussion Forums => Iron Chelation Corner => Topic started by: Sharmin on March 04, 2009, 07:38:51 PM
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Andy,
Little A had his ivig treatment today - and before his treatment he had his blood & urine tests done.
His ALT level was 53 (normal = 1 - 35) - is this something to be concerned about?
everything else seemed normal - although some results are pending. His hg 5 days post tx is 134 and his vitamin D levels are pending.
I am concerned about the liver enzyme - ALT level,
Thank you,
Sharmin
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It's fairly common to have raised ALT levels while on Exade but these levels are of no danger when slightly above normal. This is no problem at the current levels.
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Thank you Andy,
His levels have been fine since he started exjade July 30/08 - so I panicked when I saw this.
His phosphate levels were normal and I am happy with his hg for now. I hope that over time receiving dna matched blood will allow his antibodies to calm down. He has also been using nigella and colostrum for 1 week - I wonder if this may help his hg. If his hg shows signs of dropping too quickly we will start ritux immediately. As you know his Dexa was normal, but we are still awaiting his cardiac MRI results.
I am also eager to get the results of his vit D so that we can give him the megadoses as required.
Sharmin
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I am glad the levels Little A has are not a concern as of now. My question is (and I know this is a broader question) what would be the ALT level where one should start thinking of lowering the dose or stop taking Exjade?
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Thanks Narendra,
I am wondering the same thing myself. I have read somewhere that in patients that halted exjade during the trials their ALT levels were 5X the upper limit. The doctor in Oakland will be getting back to me about the results soon as well. I will post their indications.
Sharmin
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hi
my son on asunara. started 3 months now. before sgpt and sgot were ok just normal. now suddendly they had gone up to 157 and 90 respectively. so should we do anything or this is happenin to every1.
regs
micky
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Micky,
It does happen with Asunra,my daughter is also taking it and her SGPT is a bit high too,can you tell me what was the time when the test was done? SGPT should be checked after the child has rested and his activity level is high,preferably in early morning.
Zaini.
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hi
test were done in the morning when we wne for BT around 11.30 am.
thanx for answrin. any way to reduces these levels.?
regs
micky
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Micky,
I don't exactly know what can be done to reduce these levels,i think they are supposed to go back to normal with time being,what did your doctor say? Are you giving Nigella to your son? It might help.
Zaini.
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what is NIGELLA ?? PLEASE TELL ME I DONT KNOW
NEVER HEARD EVEN
REGS
MICKY
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Hi Kabir ,
Nigella = Kalonji, which is a herb widely available here in south asia , here it ussed in cooking as spice as well .. you can easily find it ...
(http://upload.wikimedia.org/wikipedia/commons/thumb/6/6a/Nigella_Sativa_Seed.jpg/180px-Nigella_Sativa_Seed.jpg)
In English, Nigella sativa seed is variously called fennel flower, nutmeg flower, Roman coriander, blackseed, black caraway, or black onion seed. Other names used, sometimes misleadingly, are onion seed and black sesame, both of which are similar-looking but unrelated. The seeds are frequently referred to as black cumin (as in Bengali kalo jira), but this is also used for a different spice, Bunium persicum. The scientific name is a derivative of Latin niger "black".[1] An older English name gith is now used for the corncockle. In English-speaking countries with large immigrant populations, it is also variously known as kalonji (Hindi कलौंजी kalauṃjī or कलोंजी kaloṃjī), kezah Hebrew קצח), chernushka (Russian), çörek otu (Turkish), habbat albarakah (Arabic حبه البركة ḥabbatu l-barakah "seed of blessing") or siyah daneh (Persian سیاهدانه siyâh dâne)or كلونجى in urdu
all that stuff is quoted from Wikipedia ...
Best Regards
Umair