Thalassemia Patients and Friends
Discussion Forums => The Spotlight => Topic started by: Dharmesh on May 29, 2012, 08:03:12 AM
-
I am Dharmesh 27 Yrs old living in Gujarat, India
Diagnosed Thal. Major at an age of 3 months, Diabetes in March 2006 right now on Asunra 1600mg daily + Folic Acid + Calcium + Insulin (twice a day). BT 1 unit at every 9-10 days. S.ferritin is climbing high too much at around 8000ng/ml. I have completed B.com and CA PE-II.
I am having lovely and caring family because of my father and mother i am able to reach at this stage which was looking quiet impossible before 27 years. At that time even doctors were predicting the age of thal major at maximum 12. But with the grace of mother, father and God this has became fact.
So this is my story
Awaiting your reply
-
Hi Dharmesh,
What is your weight and for how long has your Asunra dose been 1600 mg/day?
-
Welcome Dharmesh!
-
Hi Dharmesh,
As we chat first here (we're from same state), nice to meet you.
And its fantastic, did you completed inter CA? If yes, how much groups of final CA are completed?
And yes, the task that was seemed extremely blatant that Thal Majors cannot live more has changed way too much now. :)
You also have diabetes? Me too. At what ferritin levels did you got diabetes? I take 5 insulins a day btw. I possess it since January, 2009.
Nice to meet you, again. :)
Keep in touch.
-Pratik.
-
hi pratik,
i have completed CA Professional Education -II & CA Professional Education -I erstwhile known as CA Intermediate and Foundation respectively the toughest one. Then i completed the 3 yrs articleship training and GMCS and so on......
In 2006 March 28/29 i became more sweet due to IDDM , ferritin was around 4000-5000 ng/ml despite of taking desferal since 1990.
I am taking two shots daily. why u r taking it 5 times?
BTW, there are some thal. major having diabetes at an age of 7 :( so u n me are more blessed
Sweet dharmesh
-
Hi Dharmesh,
What is your weight and for how long has your Asunra dose been 1600 mg/day?
Hiiiiiiii Andyyyyy,
Weight 48.5Kgs
Since last 3 weeks on 1600mg/day.
Coz not able to increase the dose due to allergies, skin rash ooohhh(that is more painful than thal.major) due to asunra and high sugar level.
From yesterday i started splitting 800+800mg and 1200+800mg every alternate day
So avg. dose will be 37.5mg/kg/day.
awaiting your suggestions
-
Welcome Dharmesh!
Hi Bobby,
Thanx for warm welcome.
-
Oh Dharmesh, you caught Diabetes around 4500 only? I was around 5000 or 5500 I guess.
Are there any chances to it go if our iron levels goes down? What you think?
-Pratik.
-
Dharmesh,
I think splitting the dose may make it easier regarding the rash and side effects. The dose is good and should provide better results than 30 mg/kg. If progress isn't seen after 6 months or so, you should consider combination chelation, using desferal and Kelfer.
-
Oh Dharmesh, you caught Diabetes around 4500 only? I was around 5000 or 5500 I guess.
Are there any chances to it go if our iron levels goes down? What you think?
-Pratik.
it was in range of 4000-6000ng/ml approx consistently higher( i don't write exact report coz exact reporting of s. ferritin is myth :rotfl). some unfortunate patients caught by diabetes in first decade of life we are more lucky than them :rolleyes
2. always expect miracle , i have seen such kind of miracle which are increasing our faith, believe in god. ALL YOU NEED TO DO IS BELIEVE STRONGLY IN GOD :biggrin
-
Dharmesh,
I think splitting the dose may make it easier regarding the rash and side effects. The dose is good and should provide better results than 30 mg/kg. If progress isn't seen after 6 months or so, you should consider combination chelation, using desferal and Kelfer.
Hi Andy,
Thanx for the expert advise regarding the dose.
But combination therapy as far as kelfer concern, when it was launched in india, i started it and got the joint pain and stopped kelfer or L1.
Before 5 years sometime i was taking kelfer i don't remember it exactly but that had caused much acidity etc.
As regarding asunra right now mild catract has been developed in my eye. So all the three chelators are giving me unwanted side effects since long.
-
Is desferal an option for you? Combinations of desferal and low dose kelfer can be effective, as can desferal and Exjade together. Low dose kelfer can reduce the joint pains.
-
Is desferal an option for you? Combinations of desferal and low dose kelfer can be effective, as can desferal and Exjade together. Low dose kelfer can reduce the joint pains.
Hi Andy,
Truly speaking, I hate desferal :mad
Desferal and Exjade together? ??? Just have heard from 1 doc. here but not having much info. Anybody is taking Exjade and Desferal (I.V. or I.M.?) together? Whether doc prescribe it?
Please throw some light on the issue.
Dharmesh
-
There have been various small trials in different countries combining desferal and Exjade. They all show the same thing. The combination works better to reduce ferritin and it is safe. I know one woman whose life was saved by this shortly after Exjade was released. Congestive heart failure was reversed. Her doctor prescribed this for her even though there were no trials yet. It was a matter of saving the patient and we can't wait for trials. Danielle, our other administrator has also used this combination with success. Baal also has used all combinations of chelators. Sharmin's son took part in a US trial and all went well. I do not hesitate to recommend it, because your lives are far more important than waiting for long term trials.
-
There have been various small trials in different countries combining desferal and Exjade. They all show the same thing. The combination works better to reduce ferritin and it is safe. I know one woman whose life was saved by this shortly after Exjade was released. Congestive heart failure was reversed. Her doctor prescribed this for her even though there were no trials yet. It was a matter of saving the patient and we can't wait for trials. Danielle, our other administrator has also used this combination with success. Baal also has used all combinations of chelators. Sharmin's son took part in a US trial and all went well. I do not hesitate to recommend it, because your lives are far more important than waiting for long term trials.
Hi Andy,
What should be the composition of schedule of combi. therapy Asunra & Desferal?
-
The normal dose of Asunra should be used daily. This should be supplemented with desferal 2-5 times per week, depending on the severity of the iron load. It is best if true iron load can be determined by liver and heart MRI.
-
The normal dose of Asunra should be used daily. This should be supplemented with desferal 2-5 times per week, depending on the severity of the iron load. It is best if true iron load can be determined by liver and heart MRI.
Hi Andy,
Before going towards combi. therapy of Asunra + Desferal , i think that i should wait for 6 months to see the effect of maximum as well as splitted dose of Asunra. As i have just increased the dose from 1200mg to 1600mg since one month before. And now i am taking appox. 1800mg. daily. So , am i right to give time to Asunra?
-
Yes Dharmesh. I feel one big problem with Exjade or Asunra is that patients often abandon the drug before giving it enough time to show results.
-
Yes Dharmesh. I feel one big problem with Exjade or Asunra is that patients often abandon the drug before giving it enough time to show results.
Thanx Andy for reply,
Want to know that whether the Asunra remove iron from heart? Because it remove tissue iron than how the iron running in blood get removed which can cause reduction of S.Ferritin? ??? ???
-
Yes, Exjade has been shown to be effective removing iron from the heart and other organs. It removes iron throughout the body, including free iron in the blood. It is not as effective as deferiprone (Kelfer, Ferriprox) at removing heart iron, but over time it is effective.
-
Hello,
My S.Ferittin's Latest Report on 28/05/2012=15560 ng/ml
and previous reports are 15/03/2012=6870 ng/ml and 29/11/2011=6129 ng/ml
Whether this kind of large fluctuation is possible?(From 6870 to 15560 ng/ml within so short period)
Dharmesh
-
This is the second time this week that someone from India has reported ridiculous ferritin scores to me. The other person is chelating 24/7 with desferal. I am prone to think that it is the lab and not the patients. The other patient's doctor even told her that the score could not be accurate. Is it possible to get tested at a different lab?
-
This is the second time this week that someone from India has reported ridiculous ferritin scores to me. The other person is chelating 24/7 with desferal. I am prone to think that it is the lab and not the patients. The other patient's doctor even told her that the score could not be accurate. Is it possible to get tested at a different lab?
Yeah, defenately i will try another lab and i am sure the last report of 15560ng/ml s.ferittin is wrong. I am on regular chelation since last 22 years but with low dose and this jump is not possible from 6870 to 15560 ng/ml :rotfl
Please pray for me to have a good report of s.ferittin.
I will update report soon
Dharmesh
-
Hi Andy,
My latest report today S.Ferritin 6440ng/ml done in another lab.
Still an existing chellange to bring it to 440 ng/ml.
Dharmesh
-
I think you should consider taking desferal a couple times each week in addition to Asunra.
-
Hi Andy,
How many desferal injection to be taken in a week in addition to Asunra?
Right now i am taking Asunra twice a day so if i take Desferal in the evening then i have to skip Asunra on that particular evening? Or I have to take Asunra and Desferal both at the same time?
Need your guidence.
Dharmesh.
-
You can take both at the same time. It won't be a problem. Take whatever you can manage. I would suggest 2-3 times per week.
-
Hi Andy,
Don't be shocked please
Heare is my T2* Score
Heart Severe= 7.1
Liver Severe= 370
On 2000 mg Asunra
Weight 47.5 Kgs
Doctor Suggested to take 2400 mg Asunra for temporary 1 month
Otherwise will add Desferal
Dharmesh
-
Dharmesh,
The scores are of great concern, but I have seen similar reversed by a total commitment to chelation compliance. Ideally, combination therapy should be used. High dose Exjade or Asunra, at 40 mg/kg has shown to be effective for reducing high iron loads, but side effects can make this a difficult long term strategy. I would definitely recommend adding desferal at least twice weekly. I have seen patients turn things around using various strategies. These are some of the strategies.
Desferal 7 days a week for at least 12 hours each time.
IV desferal 24/7 and kelfer (Ferriprox).
Exjade at maximum dosage along with desferal several times per week.
All 3 chelators in combinations of no more than 2 at one time (this method worked well for an experienced patient who developed this on his own).
The key is a total commitment to chelation. There can be no excuses. Chelation has to come first in your life. A thal mom I know used desferal 7 days a week. She started with a T2* of 8. After one year, it was 13.8. After two years it was over 20.
Stay committed. Report your progress and lean on us for support. You can do this, so don't let the scores scare or depress you. I have seen patients with ferritins over 13,000 bring them down to under 1000 and even much lower by staying focused. You can and will succeed as long as you decide you will.
-
Hi Andy,
Thank You for your such in-depth advice.
I am going to start Combination Therapy within this week.
I will start Desferal and Asunra.
Desferal atleast twice in a week and Asunra 2000mg daily.
Exjade at maximum dosage along with desferal several times per week.( What is the mean of maximum dose 30mg/kg or 40mg/kg?)
Dharmesh
-
Hi Dear Andy,
I started Combination Therapy with Asunra (1200+800=2000mg daily) + Desferal S.C.
I want to take 12 to 15 Desferal (500mg each) in a week.
Have started one tablet daily to tackle mild heart pain.
Is the dosage is correct?
About Asunra i want to ask is that should i take 1600mg or2000mg or2400mg daily in addition to desferal? My weight is 48kgs.
And i hope that definitely i will give a good news regarding reduction of iron overload within some months.
And i would like to say stop to iron overload :stopmad
Thanks.
-
Dharmesh,
Take between 1600 and 2000 mg Asunra daily. This will depend on well, you tolerate Asunra. Intensive chelation is needed. When you take desferal, take 100-200 mg vitamin C when you start, so that more iron is released. Do not take higher doses of C.
-
Dharmesh,
You also have heart pain? Like what? Did you got it diagnosed or checked up?
-
YES,
I have very tiny, mild pain sometimes in the heart due to iron overload in heart as per T2* MRI.
Cardiac Physician prescribe me 1 medicine for it before some days. Now i feel better.
-
Dharmesh,
You also have heart pain? Like what? Did you got it diagnosed or checked up?
Pratik,
You also have the same pro?
-
Dharmesh,
Take between 1600 and 2000 mg Asunra daily. This will depend on well, you tolerate Asunra. Intensive chelation is needed. When you take desferal, take 100-200 mg vitamin C when you start, so that more iron is released. Do not take higher doses of C.
Hi Andy,
I have started combination therapy with Asunra and Desferal. I am taking 2000mg Asunra and 1000mg Desferal daily. I have stomach discomfort after starting use of both the chelators. What should i require to do to resolve this discomfort?
Dharmesh.
-
I assumne you are splitting the dose, so I suggest only taking half the Asunra dose for a few days and see how your stomach responds. What are you using to mix the Asunra in? Are you aware that it can be taken with a variety of soft foods, in addition to liquids.
-
I assumne you are splitting the dose, so I suggest only taking half the Asunra dose for a few days and see how your stomach responds. What are you using to mix the Asunra in? Are you aware that it can be taken with a variety of soft foods, in addition to liquids.
Yeah i am splitting the dose(1200+800mg), I have skip today's evening dose and will skip tomorrow morning's dose.
I am using Juice of a fruit identical to Orange(It is ditto like Orange but i don't know the exact word for it in English)
Yeah i am aware about other soft food to mix of Asunra but don't know about exact food iteam. Thalpal make me aware about it. Thanks.
The problem was started when i started Desfeal in addition to Asunra.
So now i have skipped Asunra and Desferal. I will restart it tomorrow with half dose if everything goes well.
Thanks for Suggestion.
Dharmesh.
-
YES,
I have very tiny, mild pain sometimes in the heart due to iron overload in heart as per T2* MRI.
Cardiac Physician prescribe me 1 medicine for it before some days. Now i feel better.
Hi Dharmesh, yes, I do have pain and recently it is blooming lately. Sometimes I feel like attack or someone is pinching my heart with a needle, I would get these T2 tests done within a month from now and see where I stand, am scared a lot though. I was never scared in my life but these heart pains makes me depressed sometimes.
What medicine did your physician described?
-Pratik.
-
First of all i want to say is that don't worry , don't be depressed. Because before 2 weeks i was feeling the same problem , identical situation same like you. Now i feel much better. Ok.?(FYI in rajkot there are so many patients are taking the same kind of pill for smooth heart functioning.)
What exactly happen to me was that my echo cardiography report was normal but MRI show severe iron overload and i consult my pediatrician and he advised me to cousult local cardiac physician and then he prescribed me the tablet.
I don't want to give the name because there are two different drugs to tackle this pro. i have to take only one. and the dose is depending on many things.
All you have to do is1. just consult your Thal. specialist doc. 2. Do MRI (Don't postponed it like me , i postponed it for 4 to 5 years :wink and due to that mistake i am taking the heart pill)
The pain will be resolved within one or two weeks i believe but consult your doc quickly.
Because iron damage the organ continuously and i suffer the pain for 2 - 3 months.
But i hope you will not repeat the mistake i did.
Update us and feel free to ask. Bye sweetu.
Dharmesh.
-
First of all i want to say is that don't worry , don't be depressed. Because before 2 weeks i was feeling the same problem , identical situation same like you. Now i feel much better. Ok.?(FYI in rajkot there are so many patients are taking the same kind of pill for smooth heart functioning.)
What exactly happen to me was that my echo cardiography report was normal but MRI show severe iron overload and i consult my pediatrician and he advised me to cousult local cardiac physician and then he prescribed me the tablet.
I don't want to give the name because there are two different drugs to tackle this pro. i have to take only one. and the dose is depending on many things.
All you have to do is1. just consult your Thal. specialist doc. 2. Do MRI (Don't postponed it like me , i postponed it for 4 to 5 years :wink and due to that mistake i am taking the heart pill)
The pain will be resolved within one or two weeks i believe but consult your doc quickly.
Because iron damage the organ continuously and i suffer the pain for 2 - 3 months.
But i hope you will not repeat the mistake i did.
Update us and feel free to ask. Bye sweetu.
Dharmesh.
Hi Dharmesh, thanks for the reply. Well, I won't definitely start taking it right away, but I just wanted to know more about this and consult/talk with my Thal doctor (Physician) who also happens to be a very fine heart/cardiac physician and a doctor. Hence I just wanted to ask the name of the pill and also how much mg you take and consult/talk with them. Just PM me the pill name (both, also tell one which you're taking) and how much mg you take? I would ask the physician and would get advice once again after T2 is done.
And don't worry, I won't delay now. I didn't heard about T2 function yet or I would have done it very long ago. Day after tomorrow (Saturday), my transfusion is scheduled. Thereafter, next after 21 days, when my transfusion happens, I am gonna get T2 and liver function done. So basically within around 25 days. Although, this time I am gonna get Color Doppler test done most probably to see how heart is functioning. I got this last done on around 28th or 30th January, 2009 when I got diabetes.
Also one more question about heart pain, did you also felt that during heart pain, right from heart in front, it used to pain in the same straight line of heart till back side as well? Because I do feel this way many times. While even writing this post, my heart is paining.
Last question, did your heart pain went away? I mean that medicine would help solve the issue? Am also feeling this since past 2 months only. :/
-Pratik.
-
Hi Pratik,
1.T2* Score that is the result of the reporting. It is simply MRI of Cardiac and Liver Iron Assessment for Thalassemia Protocol.(to be done annually). You know about MRI?
2.Don't know about color doplor for heart. Are you talking about 2 D Echo cadrdiography? But let me share u my personal experience. My Echo cardiography is absolutely normal and still i was have pain in heart. ??? ??? So inspite of having much iron overload in heart and liver these organ try to work well and normally. so i believe Echo cardiography my mislead us because it shows the function of heart not the iron deposited in heart.
Though i am not a doc. i can just share my experience so if doc. suggest you the doppler then u should act accordingly.
3. For the pain in heart, i believe 99.99% it is due to iron overload. When iron deposited in small veins of heart , it causes pain. Yes there was continuous pain at one point in my heart after having started at for half or one seconds early and then duration was increasing.
4. Now i am taking the pill since last 7 days, have much relief aprox. 80%.
5.I was having the same pro. while writing my post earlier. but now no pain.
WHAT I WANT TO SAY AND FINISH IS THAT DON'T WASTE THE SINGLE HOUR. CONSULT YOU R DOC. DO MRI FOR CARDIAC AND LIVER IRON ASSESSMENT IN AHMEDABAD. AND START THE PILL. SEE PM
AND THE MIGHT BE DUE TO LOVE. ARE YOU IN LOVE WITH YOUR GF? HOW MANY GF U HAVE :rotfl :rotfl
BE SERIOUS, CONSULT YOU DOC.ON SUNDAY. WHY DON'T U CALL ME?
DHARMESH
-
Yeah i am splitting the dose(1200+800mg), I have skip today's evening dose and will skip tomorrow morning's dose.
I am using Juice of a fruit identical to Orange(It is ditto like Orange but i don't know the exact word for it in English)
Yeah i am aware about other soft food to mix of Asunra but don't know about exact food iteam. Thalpal make me aware about it. Thanks.
The problem was started when i started Desfeal in addition to Asunra.
So now i have skipped Asunra and Desferal. I will restart it tomorrow with half dose if everything goes well.
Thanks for Suggestion.
Dharmesh.
Hi Andy,
Got relief from Stomach discomfort for one day (had taken just 800mg asunra once in a day.)
Today have mild stomach discomfort(had taken 1200mg Asunra instead of 800mg Yesterday.) I am mixing the Asunra with juice of 1 piece Sweet Lime and appropriate qty of water
What i would like to do is that i will try it in morning. from two days i am taking it in evening.
Is it okay?
Need your suggestion.
Dharmesh
-
Dharmesh,
Stomach problems when raising the dose of Exjade/Asunra are common, so any method you can find to work yourself up to the full desired dose is exactly what you need to do. Patient ingenuity is how thals survive, so find what works for you, as long as in the end, you get up to your desired dosage.
-
Hi Dharmesh,
Just came here to update the situation a little bit. I believe I don't have heart pain (or if any, very very mild) but GASTRIC (Acidity) problem. I am taking acidity pills and Acidity syrup (Jivan Mixxer) and I feel a little relaxed than yesterday.
Hope for best. :biggrin
Though, am gonna get T2 MRI done in under 25 days. Just got transfused today in morning.
-
Hi Pratik,
Many times it happen that we get confused between heart pain and acidity. One doc. also said to me before some days that my pain was due to gas trouble :biggrin
So if u are sure then it is ok.
Dharmesh
-
Dharmesh,
Stomach problems when raising the dose of Exjade/Asunra are common, so any method you can find to work yourself up to the full desired dose is exactly what you need to do. Patient ingenuity is how thals survive, so find what works for you, as long as in the end, you get up to your desired dosage.
Yes ,
You are absolutely right Andybrother.
I am also thinking in the same direction try trying to find the ideal schedule for me by trial and error method.
Will update you.
Dharmesh
-
Hi Very Speedy Andyyy,
My Desferal Pump is running now while i want to ask you that
Whether i required any report in addition to CBC, ALT, S.Creatinine and Ferittin as i have added Desferal with Asunra with my chelation schedule? Any other monitoring required for this combination? Perhaps i am going for reporting tomorrow.
Dharmesh.
-
If you use desferal for an extended period of time, the annual vision and hearing tests should also be done.
-
If you use desferal for an extended period of time, the annual vision and hearing tests should also be done.
Yes , i just decided yesterday to have 3 desferals(for 15-20 hours) instead of 2 desferal(for 12 hours) for 3 to 4 days.( I want S.Ferritin to 440ng/ml from 6440ng/ml by any mode.and think that 40-45 desferals in a month won't be suffice)
About Vision and Hearing( I can look into future and can hear voice of heart :biggrin)
I was realized at an age of 17 or 18 that i have some kind of hearing problem. Then found out the reason is desferal and it has cause HIGH FREQUENCY HEARING LOSS at an age of 5 years soon after starting desferal therapy. I wanted to cure this problem as sometime it becomes more painful to me than Thal.
Do you have any suggestions or medicine or the hearing machine is the only solution.?
I was taking Desirox and then Asunra from 2008. In April i went for eye examination and doc. seen CATARACT in my eyes. and has suggested me for bi-annual examination of eyes.
Thank you,
Dharmesh
-
Yes , i just decided yesterday to have 3 desferals(for 15-20 hours) instead of 2 desferal(for 12 hours) for 3 to 4 days.( I want S.Ferritin to 440ng/ml from 6440ng/ml by any mode.and think that 40-45 desferals in a month won't be suffice)
About Vision and Hearing( I can look into future and can hear voice of heart :biggrin)
I was realized at an age of 17 or 18 that i have some kind of hearing problem. Then found out the reason is desferal and it has cause HIGH FREQUENCY HEARING LOSS at an age of 5 years soon after starting desferal therapy. I wanted to cure this problem as sometime it becomes more painful to me than Thal.
Do you have any suggestions or medicine or the hearing machine is the only solution.?
I was taking Desirox and then Asunra from 2008. In April i went for eye examination and doc. seen CATARACT in my eyes. and has suggested me for bi-annual examination of eyes.
Thank you,
Dharmesh
Hi Dharmesh,
Your hearing is affected too? Well, I once in 2009 had a misconception that due to Asunra/Exjade, I had a little problem in hearing but I went to an ENT and got the hearing test done and they were perfectly normal.
I also get my eye tests done every year.
-
Hi Pratik,
Both Asunra and Desferal does affect Hearing and Vision ability, Patient require yearly vision and hearing checkup.
Generally, the person who is talking to me do not realize that i have this kinda pro.
-
Dharmesh,
All 3 chelators in combinations of no more than 2 at one time (this method worked well for an experienced patient who developed this on his own).
Dear Andy,
I need some more Information on the above option of all the three chelators in combinations. Does it means that these 3 chelators are to be taken daily at appropriate time? or two chelators(Asunra+Desferal) combined for some weeks, months and then after another two chelators(Desferal+Kelfer) for some weeks, months? How that person has managed it can u please elaborate it?
Please , Please guide.
Dharmesh
-
Our member, Baal did this. He used two chelators at a time but never more than two. He alternated the chelators over time, always taking two, but never more than two at the same time. This was his own method and not approved by any doctor, but it helped him reduce side effects of the drugs.
-
Hi Andy,
Thank You for throwing lights on this issue. I was thinking that 3 chelators in 24 hours.
Whether Baal has used combination of both the oral chelators? i.e. L1 & DFX. What was the results?
Dharmesh
-
No, Baal never used 3 chelators at the same time. I would not suggest 3 different chelators within such a short period. The point in changing the combinations is to minimize side effects, so this is something he did periodically.
-
Hi Andy,
Right now i am on ONLY 1200MG ASUNRA and Desferal(i took 41 desferals in a month). Unable to tolarate higher dosage of Asunra because it's causing stomach discomfort.
Doctor has advised me to take 1600mg Asunra in split dosage.
I want to keep the dose at this level for sometime. Is it ok?
Another question , How many minutes the Asunra take to fully dissolved? Should i wait for half an hour to dissolve it ? Right now i am taking it with water.
-
Hi Andy,
My latest report today S.Ferritin 6440ng/ml done in another lab.
Still an existing chellange to bring it to 440 ng/ml.
Dharmesh
hahahaha
S.Ferritin on 16/07/2012 11620ng/ml :biggrin Vs 6440ng/ml last month and in the same lab. :rotfl :rotfl
-
I suspect something like an infection or inflammation is causing the higher readings. This illustrates the importance of relying on scans for your true iron readings, as ferritin does not seem reliable in your case. And yes, I have seen this in others.
-
I suspect something like an infection or inflammation is causing the higher readings. This illustrates the importance of relying on scans for your true iron readings, as ferritin does not seem reliable in your case. And yes, I have seen this in others.
Hi Dear,
1. My WBC are below 4000 since last 2-3years.
2. Thrice After bt i got inflammation /swelling in feet and face.
Once My face was looking like a balloon.
3. I am taking half Cetrezine twice in a week for allergise or reactions of bt. My doc. said to me that this allergies is not due to Asunra but due to constant bt and adviese TSW RBC instead of plain RBC/RCC. Right now i am on LR-RCC(SAGM Method)
Please guide
-
I want to ask that why i am not finding reply from other senior members...
Where are they? Yes they might be engaged in their own issues but i am missing senior members. :sadno
-
Yes , i just decided yesterday to have 3 desferals(for 15-20 hours) instead of 2 desferal(for 12 hours) for 3 to 4 days.( I want S.Ferritin to 440ng/ml from 6440ng/ml by any mode.and think that 40-45 desferals in a month won't be suffice)
Dear if you want to have S. Ferritin lowered by that margin then I guess 3-4 days desferal isnt enough. My iron is in 7000 range and I am on 24/7 pump + kelfer. I would suggest atleast taking it 5days a week, but for optimum result it has do be 24/7 since you are also experiencing mild chest pain. And remember that its not desferal dosage that matters, but for how long you took it.
-
Dear if you want to have S. Ferritin lowered by that margin then I guess 3-4 days desferal isnt enough. My iron is in 7000 range and I am on 24/7 pump + kelfer. I would suggest atleast taking it 5days a week, but for optimum result it has do be 24/7 since you are also experiencing mild chest pain. And remember that its not desferal dosage that matters, but for how long you took it.
Hi Waleed,
Thanx for reply.
You might be right dear that the frequency and dosage are not optimal.
Exactly whenever i increases the dosage some reactions get started. It was joint pain with Kelfer before many years. Recently i increased the dose of Asunra and it causes stomach discomfort.
Another problem which i faced last night is pain in both ears, tinitus problem and it get resolved after 7 hours when desferal pump got completed.(Desferal pump was running continuously for last two days with a break of 6 hours and it cause problems)
Every chelator is causing side effects when i am rising the dose.
-
I too would like to see more participation by the senior members. There are so many questions that can only be answered by those with experience.
-
Hanumant,
From my experience, the only way to reduce side effects and get good results is to increase the amount of time desferal is on and the use of combination chelation. You need to come up with a good plan and then proper assessment through blood tests afterwards.
We can help you come up with a plan and you can discuss it with your doctor. Personally, we have found the combination of exjade and desferal to be very effective very quickly with very few side effects. You must be diligent and use the chelators very consistently but you can achieve success very quickly as well.
Most importantly your doctor must check your kidney and liver funciton every 3 weeks.
We are here to support and help,
Sharmin
-
Dear Dharmesh,
Try increasing amount of water. Make sure its atleast 5ml for every one vial of desferal and transfuse it not less than 8hours. Even then if you experience problem 'itching / rashes' on the injection site then you can increase water more than 5ml for every injection.
Secondly, I think that its not because of desferal that you are experiencing side effects but because of Asunra. Why I am saying this is because you have not been taking desferal for long time, since this is reflected in your iron levels, and even you are not taking high doses. Desferal toxicity increases when ferritin levels are very low and desferal starts disturbing you or when you are on desferal for a very prolonged time.
So far, nearly every thal I met had not seen other side effects of desferal except 'itching/rashes/lumps' on injection site.
I think you should check again, whether it is desferal or asunra causing problems.
One more experience I would like to share. In 2002/2003 I had high iron levels. Sure around 10,000. I used desferal only 24/7 and within a month ferritin was 5,000 and next month it was 2,500. Dont undermine the power of desferal, if taken correctly will yield excellent results.
Since your iron levels are very high and given your chest pains. I think you should not compromise desferal at all.
This is my suggestion. In the end, you are the boss !
-
Hanumant,
From my experience, the only way to reduce side effects and get good results is to increase the amount of time desferal is on and the use of combination chelation. You need to come up with a good plan and then proper assessment through blood tests afterwards.
We can help you come up with a plan and you can discuss it with your doctor. Personally, we have found the combination of exjade and desferal to be very effective very quickly with very few side effects. You must be diligent and use the chelators very consistently but you can achieve success very quickly as well.
Most importantly your doctor must check your kidney and liver funciton every 3 weeks.
We are here to support and help,
Sharmin
Thanx Dear Sharmin,
How is little A?
I took 2 desferal of 500mg in 10ml Distilled Water for 12 hours. I just tried to increase the time of Desferal in last week and i took 3 desferal simultaneously for 18-20 hours and i firmly believe that my ear pain was due to continuous desferal because when desferal get completed then the pain got disappear in some hours . As my hearing is affected since long but this kind of pain in ear is new for me because i have just restarted desferal before 5 weeks.
I am monitoring ALT/SGPT and S.Creatinine every 2-3 weeks continuously since 2008 when i started Asunra. In addition also Eye and Ear Check up etc.
I am going to ask the doctor about the Ear Problem.
-
Dear Dharmesh,
Try increasing amount of water. Make sure its atleast 5ml for every one vial of desferal and transfuse it not less than 8hours. Even then if you experience problem 'itching / rashes' on the injection site then you can increase water more than 5ml for every injection.
Secondly, I think that its not because of desferal that you are experiencing side effects but because of Asunra. Why I am saying this is because you have not been taking desferal for long time, since this is reflected in your iron levels, and even you are not taking high doses. Desferal toxicity increases when ferritin levels are very low and desferal starts disturbing you or when you are on desferal for a very prolonged time.
So far, nearly every thal I met had not seen other side effects of desferal except 'itching/rashes/lumps' on injection site.
I think you should check again, whether it is desferal or asunra causing problems.
One more experience I would like to share. In 2002/2003 I had high iron levels. Sure around 10,000. I used desferal only 24/7 and within a month ferritin was 5,000 and next month it was 2,500. Dont undermine the power of desferal, if taken correctly will yield excellent results.
Since your iron levels are very high and given your chest pains. I think you should not compromise desferal at all.
This is my suggestion. In the end, you are the boss !
Hi Waleed,
Yes i am taking 1 vial in 5 ml but u said that for not less than 8 hours means 16 hours for 2 vials or 8 hours for 2 vials?
Why i am feeling that Desferal is causing the pro because i just restarted it before 4-5 weeks and this ear pain disappeared when i complet the desferal.
High dose of Asunra is causing stomach discomfort so i have decided to take 1200mg for some weeks then i will increase it to 1600mg.
And ya, There is no more Chest Pain as i have started one pill for it and added desferal to my chelation programme.
Thanx for heartily reply.
-
I meant 2 vials together for atleast 8 hours. Longevity is better though. And by chest pain, my point was not about pain itself, but the signal it gives that hear is overloaded with iron. I think you should do 3vials 24/7 + asunra. I am doing 4vials 24/7 + kelfer.
-
Hi and Cool Hello to All,
Right now i am taking 1200mg Asunra and 1000mg Desferal Daily. Desferal takes atleast 10 to 12 hours. No Chest pain. Ear pain was due to infection and there was throat infection as well.
-
Hi Dear All,
My SGPT 32 IU/L
S. Creatinine 1.01 mg/dl
S. Ferritin 11452 µg/L
Still having an infection in throat and ear.
Having 4 Units Tx LR RCC(225ml each approx, still low hb)
CURRENT UPGRADED CHELATION PLAN
4 ASUNRA Total 1600mg (instead of 3)
2 Desferal Daily(12 hours/10ml d.water)
-
GETTING MORE & MORE KNOWLEDGE WHENEVER I OPEN THALPAL.
EXPLORING THALPAL
THANX LISA AND ANDY. :lovethissite
-
Dear Andy Bro,
I was thinking on this matter since many days, let me write it over here. Need your help.
To reduce iron level and ferritin level chelation is much important, but right now in my case there is iron overload and Chelation remain insufficient. What i have observed since long that it's the HIGH LEVEL OF INPUT(Blood Transfusion) in my case , i am getting 4 units a month(Approx 225ml each) which is causing iron level very up and that's why the OUTPUT (chelation) become lower in comparision of INPUT. still my hb remains low at most 8.5gm
So, what could be the reason for higher need of transfusions.?
1. I have my spleen intact, BUT It's size is not big.
2. I have some Antibody reactions(Though doc. says COOMB'S TEST WILL BE NEGATIVE).
3. I am not taking Vitamin-E
Whenever i get transfusions thenafter 2-3 days my upper abdomen(liver) area become hard. After that it gradually day by day become soft and before the day of transfusion it's ultimately become original soft. Again this process repeated as and when i got tx.
What's all these? Plz guide me.
-
Dear Andy Bro,
I was thinking on this matter since many days, let me write it over here. Need your help.
To reduce iron level and ferritin level chelation is much important, but right now in my case there is iron overload and Chelation remain insufficient. What i have observed since long that it's the HIGH LEVEL OF INPUT(Blood Transfusion) in my case , i am getting 4 units a month(Approx 225ml each) which is causing iron level very up and that's why the OUTPUT (chelation) become lower in comparision of INPUT. still my hb remains low at most 8.5gm
So, what could be the reason for higher need of transfusions.?
1. I have my spleen intact, BUT It's size is not big.
2. I have some Antibody reactions(Though doc. says COOMB'S TEST WILL BE NEGATIVE).
3. I am not taking Vitamin-E
Whenever i get transfusions thenafter 2-3 days my upper abdomen(liver) area become hard. After that it gradually day by day become soft and before the day of transfusion it's ultimately become original soft. Again this process repeated as and when i got tx.
What's all these? What should be done to up pre bt hb level? Plz guide me.
Hey Dear Andy,
Nothing to Say?
-
The upper left abdomen is where the spleen is located and your experience after transfusion sounds very much like your spleen is active in destroying the red blood cells after your transfusion. Are you using filtered blood?
-
Dear Andy,
Thankx for reply.
1. I am not using filters Set or filtered blood.
2. It is just phynotyped blood (Extended panel Cross Matching) Leuko Reduced RCC which has been started by me since June 2012.
3. I am advised to use filter set (by one doc) and Triple Saline Washed RCC (by another doc.) coz i am having allergic reactions on skin due to blood transfusions.
4. Should i use the Filter set or Triple Saline Washed RCC , which is good for me?
Plz guide, i want to see my pre bt hb at 9.5 to 10 gms%
-
A filter will remove more white cells. Since you are reacting, a filter should be tried for a few transfusions to see if your blood lasts longer.
-
Definitely i will try Filter Set.
But otherwise Saline Washed is only option?
-
Washed cells are a good option, but not quite as effective as a filter. Even with filters, fragments sometimes get through, causing reactions.
-
Just to add, I was using filter in early 2009 but eventually stopped using it, it didn't caused me any low WBC situation as I remained protected all the times, but it actually caused more troubles than any good it may do. Sometimes the blood won't just flow, maybe due to weather (cold) or some other issues, so I stopped it. And I haven't noticed any good or bad difference with or without using a filter.
I take TSW (Triple Saline Washed) PCV around 500 CC (ml) which lasts around 21 days keeping my Hb above 9 or sometimes around 9.5.
-
@ Andybro
I am going to use Bayer filters on next transfusion. Pray for me that blood lasts longer. I really need higher pre bt hb.
@ Pratikdear,
You might be using TSW RBC & not PCV. Because PCV contains White cells in addition to Red Cells. We require Red Cells only. Do check it.
-
A filter will remove more white cells. Since you are reacting, a filter should be tried for a few transfusions to see if your blood lasts longer.
Dear Andy,
There is no improvement in hb level after using filters.
Pre bt hb and post bt hb both came at 9 gm/dL, inspite having large unit of blood.
After that (in next week) pre bt come to 8.4gm/dL.
Now transfusing blood at every week(large unit and without phynotyping using filter)
Every time after tx abdomen area become hard and thenafter in some day returned to normal.
Splenectomy to be done?
-
Splenectomy should be a last resort. My opinion is don't remove the spleen unless the size is a danger. How large is your spleen?
-
Hi Andy,
Actually it is very long time i had have sonography. Old Report on Feb 02,2010
Spleen Size about 17.5 cm.
Conclusion
Moderate spleenomegaly noted
Mild hepatomegaly noted
I will go for latest Sonography of Abdoman Area.
By the way , what are the other options to improve the hemoglobin ?
Thankx
-
Regarding the liver pain or abnormalities,
you can try turmeric (Haldi/haldar) with honey.
I'm taking it these days due to throat infection and it also doesn't increase my sugar levels at all, instead I find it's helping me to manage my sugar levels.
When in past I took, my SGPT levels were very nice, 28 or so.
I plan to take this now at least 3-4 times a week.
-P.
-
Hi Dear Pratik,
Actually i am taking turmeric with Milk 365days in the morning.
My SGPT level is 32 which was staying around 65 before starting Desirox.
Just add some Ghee drops to Honey + Turmeric combination , it will work best for throat infection, in addition to it Chew Tulsi Pan daily. It's my personal experience and it works
-
Hi Andy,
Actually it is very long time i had have sonography. Old Report on Feb 02,2010
Spleen Size about 17.5 cm.
Conclusion
Moderate spleenomegaly noted
Mild hepatomegaly noted
I will go for latest Sonography of Abdoman Area.
By the way , what are the other options to improve the hemoglobin ?
Thankx
Hi Andy,
My today's report
Sonography Abdomen Screening
Conclusion:
Hepato-splenomegaly.
Spleen measures about 172mm.
Please Help. Should i go for splenectomy?
-
I would not suggest splenectomy yet. It is large, but not dangerously so. I would say give i some time and also talk to the doctor about the antibody reaction that cause the high rate of blood turnover. We have also previously been told of some herbal remedy for spleen size. Have you tried anything like that yet?
-
Antibody reaction test COOMB Test was done before 2 years and it was Negative. Before just one month it is NEGATIVE. Whether any other test require? or shoud is go for retest of COOMB's Test , Direct and Indirect?
Regarding herbal remedy the problem is that it is not used by any other. If i take it and if there is some reactions then there will be no body to rescue me. So i am a bit afraid.
Morover i am going to start Wheatgrass tablets and Natural Vitamin E and hope it will help in hb maintaining.
Since some weeks I am taking Evion 200 and i feel that it is helping very very limited but it is. I feel that Evion is avoiding chest pain and back pain happend to me before a day of Tx.
-
The pain is usually because of low Hb, I believe. And yes, I too take Evion (Vit E brand in India) and I feel it helps me a lot. It also helps me get away and saves me from any fatigue and restlessness.
About Hb, usually, if and when, sometimes, I've low Hb, like 8 or so (in very rare cases), my legs and joints do pain, which after TX, on the next day of it, are much relieved. So yes I do believe there is some connection of pain due to Hb levels being low.
-P.
-
About Hb, usually, if and when, sometimes, I've low Hb, like 8 or so (in very rare cases), my legs and joints do pain, which after TX, on the next day of it, are much relieved. So yes I do believe there is some connection of pain due to Hb levels being low.
-P.
This is the same in my case
-
I would not suggest splenectomy yet. It is large, but not dangerously so. I would say give i some time and also talk to the doctor about the antibody reaction that cause the high rate of blood turnover. We have also previously been told of some herbal remedy for spleen size. Have you tried anything like that yet?
Hi Andy,
i am still in dilemma about spleenectomy.
My blood transfusion volume of last 3 months is exceeding 20ml/kg/month . Approx around 23ml/kg/month.
This is causing iron overload , inspite of having combo therapy of desferal (50 vials per month) and asunra (40mg/kg), the last ferritin report came at 7590 Vs 6490.
Though my health is improving and m feeling well after the six months of desferal and asunra combo therapy
My abdomen area is quiet enlarged and causing me trouble in routine.
In addition , Can vitamin E cause weight gain? i gained around 4-5 kgs after starting GNC Vitamin E ., though i like the weight gain it make desferal prick smooth and it is more convenient now (due to more muscle at thigh) but abdomen area get enlarged after starting it.
Plz guide on spleenectomy
-
Regardless of how much blood you will need, you should strive to keep your Hb above 9.5 at all times. This is actually the best thing to counter hypersplenism. Splenectomy should be the last resort, as there are long term problems associated with splenectomy. For some perspective on how big a spleen can get before splenectomy is the course of action, Nur's was 25 cm when it was removed. Don't rush into a decision on splenectomy.
Vitamin E can help one gain weight if one is deficient in vitamin E, and almost all thals tested are deficient. I do not believe it aids weight gain when levels are sufficient.
Keep chelating and don't be concerned about single ferritin readings. Be confident that you are on the right course and iron is being removed from your organs.
-
Hi D,
Sorry to hear that.
But gaining weight is such a beautiful thing. :D
I'm doing weight training these days (at home though) to gain weight specially and build a good physique. And I feel great after working out. I hope you curb these problems soon. :wink
-P.
-
Regardless of how much blood you will need, you should strive to keep your Hb above 9.5 at all times. This is actually the best thing to counter hypersplenism. Splenectomy should be the last resort, as there are long term problems associated with splenectomy. For some perspective on how big a spleen can get before splenectomy is the course of action, Nur's was 25 cm when it was removed. Don't rush into a decision on splenectomy.
Vitamin E can help one gain weight if one is deficient in vitamin E, and almost all thals tested are deficient. I do not believe it aids weight gain when levels are sufficient.
Keep chelating and don't be concerned about single ferritin readings. Be confident that you are on the right course and iron is being removed from your organs.
But Hypertransfusion lead to more RBCs destruction in the spleen even after maintaining the pre bt hb at 9.5gms.
Can Vitamin E or excess dosage be harmful to Liver?
Above all , i am getting confident, strong and strength full day by day. Iron is definitely removed by combo. therapy and organs are becoming clearer. Body is giving signs of it. :smiley
The only problem is Hyper transfusion because it require hyper chelation, even there are others problem also associated with transfusions like HCV .. etc.
Can you tell me when i will off from Desferal? or Single chelator (Asunra) can be sufficient to maintain iron balance in my case due to this huge volume of blood transfusion, when iron come below 1000ng/ml?
-
Can two large units (total approx 650 ml , RCC) be transfused at 9.5gm hb? Generally my hb increases by 2.4 gm/dL after transfusion of 2 large units.
It put a load on heart when hb is 9.5gm/dl?
-
Moreover,
I have joined GYM, and it's exactly complete 1 month. :biggrin
I use some machines at GYM but without Weight. The core to be considered , the most important part, is the DIET.
Pratik,
No one can believe that our Gujarati diet , pure vegetarian, can be so much qualitative. Without increase the quantity of food , it can be more nutritious.
I am on such diet since 2009 and it is helping me when i started combo therapy to reduce iron level.
-
Moreover,
I have joined GYM, and it's exactly complete 1 month. :biggrin
I use some machines at GYM but without Weight. The core to be considered , the most important part, is the DIET.
Pratik,
No one can believe that our Gujarati diet , pure vegetarian, can be so much qualitative. Without increase the quantity of food , it can be more nutritious.
I am on such diet since 2009 and it is helping me when i started combo therapy to reduce iron level.
Damn D, you hided that from us. :biggrin
I plan on hitting the Gym in near future soon enough, gotta shape a nice body.
And yes, diet is most important and that's why I'm trying to max out protein intake and calories and lower the carbs. That's the very reason I've ordered Whey protein powder.
Well, as you're going to Gym, why not lifting the weights? Or that your trainer told no unless he prepares you for that (as normally Gym trainers don't recommend to lift weight until they make our body suit to it with training for 1-2 months). Your muscles can only expand when you train them.
When you lift weight, muscle breakdown occurs, and so more and more cells are transported or generated at that site to form a new tissue and that is how the muscle mass keeps on increasing. I was very fancy about exercise and gym since childhood.
-P.
-
Can you tell me when i will off from Desferal? or Single chelator (Asunra) can be sufficient to maintain iron balance in my case due to this huge volume of blood transfusion, when iron come below 1000ng/ml?
Dharmesh - Once the levels go below 1000 you can go on a single chelator as many thals have done. There are thals who had to lower the Exjade dose once their ferritin levels were in the range of 500. Until then combination therapy will greatly help you get rid of the iron from your body.
-
Damn D, you hided that from us. :biggrin
I plan on hitting the Gym in near future soon enough, gotta shape a nice body.
And yes, diet is most important and that's why I'm trying to max out protein intake and calories and lower the carbs. That's the very reason I've ordered Whey protein powder.
Well, as you're going to Gym, why not lifting the weights? Or that your trainer told no unless he prepares you for that (as normally Gym trainers don't recommend to lift weight until they make our body suit to it with training for 1-2 months). Your muscles can only expand when you train them.
When you lift weight, muscle breakdown occurs, and so more and more cells are transported or generated at that site to form a new tissue and that is how the muscle mass keeps on increasing. I was very fancy about exercise and gym since childhood.
-P.
Oh and I also forgot to mention, "the increased weight" that you mentioned is likely to be result of Gym/weight training.
-P.
-
Dharmesh - Once the levels go below 1000 you can go on a single chelator as many thals have done. There are thals who had to lower the Exjade dose once their ferritin levels were in the range of 500. Until then combination therapy will greatly help you get rid of the iron from your body.
Hello Narendra,
Thanks for the reply.
I agree with you and when Fe is below 1000 single chelator will be enough.
But actually those who are on single chelator, none of them would be taking 4 large units every month like me.
All the Thals to whom i know personally are on mostly on 2 small units of blood every month, also they are spelenectomised and i am not, they have achieved the goal of Fe <1000ng/ml
Do you think that Asunra alone can remove iron increased by 4 large(approx volume 1250 ml) units per month. This is my point to be considered.
Thanks.
-
Damn D, you hided that from us. :biggrin
I plan on hitting the Gym in near future soon enough, gotta shape a nice body.
And yes, diet is most important and that's why I'm trying to max out protein intake and calories and lower the carbs. That's the very reason I've ordered Whey protein powder.
Well, as you're going to Gym, why not lifting the weights? Or that your trainer told no unless he prepares you for that (as normally Gym trainers don't recommend to lift weight until they make our body suit to it with training for 1-2 months). Your muscles can only expand when you train them.
When you lift weight, muscle breakdown occurs, and so more and more cells are transported or generated at that site to form a new tissue and that is how the muscle mass keeps on increasing. I was very fancy about exercise and gym since childhood.
-P.
Hey Dear Pratik,
It was my plan since 2009 to join the Gym which became fact in Dec.2012.
When my body start giving me signs , then i thought to join it. And i got these signs after 6 months of adding desferal with Asunra. My diet is also heavy since 2009 but only natural milk, cereal protein(you can get the recepe of the diet) and not any Whey Protein (I think it is bull shit, i am getting result without it and natural qualititive diet can fetch the desired result). I never cut carbo. in my diet, it is the key to Gym, and my result is seen by you.
Machines have atlest 5 kgs weight by default, so i don't add more weight to it as my body don't permit
-
Oh and I also forgot to mention, "the increased weight" that you mentioned is likely to be result of Gym/weight training.
-P.
No
The reason is God's blessing, diet aided by reduction in body iron and Combo therapy
-
When you lift weight, muscle breakdown occurs, and so more and more cells are transported or generated at that site to form a new tissue and that is how the muscle mass keeps on increasing. I was very fancy about exercise and gym since childhood.
-P.
I always try harder to ensure that muscle breakdown happenes never. When u lift weight beyond your capacity , any exercise done in speed including walking in garden or trade mill, or your carbo. intake is improper, or all of the above then there will be muscle breakdown.
The process of forming of tissues called metabolism and it happen when iron is under control and qualititive diet is taken full of Carbo, protein , fat, minerals, vitamins, water and above all much oxygen.
-
This is the same in my case
Last time the pain was not there even when my pre bt hb dropped to 7.6gm/dL.
I think the iron is decreasing.
-
Hi Andy , P and All,
My splenectomy done on 11th July. :wink
-
How are you feeling? Any change in blood requirement yet?
-
Healing is almost done, dear Andy bro.
No bt taken after operating. Lastly 2 units taken on during operation on July11. Overall appetite recovery is slow i think.
It was 20cms n 1 kg size. Chelation will start when i feel perfect nd healing cmplted. Any suggestion post op?
-
Wow D, never recognized you did splenectomy. Any particular reason? How is your Hb now? I'm surprised you didn't required transfusion since almost a month. Also was it giving you any problems or pain or such?
-P.
-
Dharmesh,
Recover fast. Are you back home from the hospital. Is your platelet with range. Keep posted.
Take care
-
Hi Dharmesh ,
Get well soon man.
-
Wow D, never recognized you did splenectomy. Any particular reason? How is your Hb now? I'm surprised you didn't required transfusion since almost a month. Also was it giving you any problems or pain or such?
-P.
Hello P,
I have had signeled abt splenectomy. Excess trans req was the reason. i was exceeding the accepted qty of bt i.e. 250ml/kg/yr
No pain. most of healing done
-
Dharmesh,
Recover fast. Are you back home from the hospital. Is your platelet with range. Keep posted.
Take care
Rashmi,
i got discharged on 6th day.
platelet r 12 L approx
-
Hi Dharmesh ,
Get well soon man.
Hello Shrikant,
Thank u :)