Thalassemia Patients and Friends

Discussion Forums => Thalassemia Major => Topic started by: Babynorth on May 29, 2013, 10:25:24 AM

Title: Siblings with thal?
Post by: Babynorth on May 29, 2013, 10:25:24 AM

Question:
Theoretically, can it be siblings where one is Thal Major and the other is Thal Intermedia?
Where these two have one or both biological parents.

Title: Re: Siblings with thal?
Post by: Andy Battaglia on May 29, 2013, 02:03:09 PM

Yes, even if they have the same set of beta globin genes, because there may be other genetic modifiers at work in the intermedia, such as a coinciding alpha deletion.

Title: Re: Siblings with thal?
Post by: Bobby on May 29, 2013, 05:28:20 PM

I am Intermedia and my sister is minor and I have a sister without Thal. We all have the same parents.

Title: Re: Siblings with thal?
Post by: Wildbill on May 29, 2013, 06:24:52 PM

Bobby:

Not to change the subject of discussion, but where do you go for Thal treatment?  Did you initially go to Childrens Hospital in Atlanta?

Just curious............I'm in Arkansas and looking into going to one of the centers, but would like to be closer to home than Oakland or Boston.

Thanks,
Bill

Title: Re: Siblings with thal?
Post by: Babynorth on May 31, 2013, 10:06:12 AM

Thank you for your answers, great help for me :-)