Thalassemia Patients and Friends

Discussion Forums => Thalassemia Minor => Topic started by: ahassuna on May 06, 2014, 12:14:01 PM

Title: please help with this Hb electrophoresis test
Post by: ahassuna on May 06, 2014, 12:14:01 PM

Hi,

This is my first time here , and i just want to know if the below  hemoglobin electrophoresis test is ok for 9 months old male.

Hb A    92.8%
Hb A2  2.9%
Hb F     4.3%
Hb S     0

thanx .

Title: Re: please help with this Hb electrophoresis test
Post by: Andy Battaglia on May 06, 2014, 11:11:23 PM

The HbF is high indicating the possibility of beta thal minor, but at 9 months t's not unusual to still see an elevated level of HbF. The HbA2 is normal, and this is usually high in beta minor. What does the CBC show for MCV, MCH, RBC and RDW?

Title: Re: please help with this Hb electrophoresis test
Post by: ahassuna on May 07, 2014, 10:57:15 AM

Thanks Andy for your reply , and this is CBC test

Hb                9.2  g/dl
Haematocrit   26.7%
MCV               73 fl
MCH              25.1 pg
RBCs              3.66  x10E6/ul
RDWSD           40.1 fl
RDWCV           13.6 %
MCHC              34.5 g/dl
platelets          372  x10e3/ul
MBV                 8.7 fl
BCT                0.109 %
PDW                10.4
WBCs              8.05  x10e3/ul
serum Iron       0.36 ug/ml
TIBC               2.8
serum Ferritine 26.7
serum calcium  9.2 mg/dl
serum ionized calcium 4.8 mg/dl
serum phosphours 5.1

i have some questions :
is there any chance that HbF change to become HbA  as you said the high level of HbF is usual in this age?
if this is beta thal minor, is he in danger?is he need any vitamins or supplements?

Thanx alot Andy

Title: Re: please help with this Hb electrophoresis test
Post by: Andy Battaglia on May 08, 2014, 02:47:49 PM

Some of the values support a diagnosis of thal minor, but not enough to say for sure. I think a hemoglobin electrophoresis should be repeated after the child has turned on year old.