Thalassemia Patients and Friends

Discussion Forums => Iron Chelation Corner => Topic started by: dip1973 on May 27, 2015, 06:18:12 PM

Title: Chelation to start
Post by: dip1973 on May 27, 2015, 06:18:12 PM

Hi,

My son 9 years old having HbE-Beta Thalassemia.He is on regular transfusion from last one and half year ( transfusion gap is 5 week).
His weight is 23 Kg,current ferritine  is 850.
we have planned to start Asunra 600mg, please need your advice / comments on this.

regards

Dip

Title: Re: Chelation to start
Post by: Bostonian_04 on May 27, 2015, 07:37:14 PM

Dip,
Based on our experience, I will suggest to start on a very low dose initially (e.g. 10mg/kg weight or so) and then gradually increase the dose to the final dosage amount. Also try to give exjade with food to minimize stomach discomfort.

Title: Re: Chelation to start
Post by: dip1973 on May 28, 2015, 03:11:49 AM

Dear Bostonian_04

Thank you for your suggestion . I am also having same opinion of starting with lower dose.

Regards

Title: Re: Chelation to start
Post by: Andy Battaglia on May 28, 2015, 11:53:37 PM

I agree. I like to see patients start at 1/3 dose for two weeks before deciding to raise the dose. A slow introduction greatly reduces the early side effects. And make sure the child stays well hydrated.

Title: Re: Chelation to start
Post by: dip1973 on May 29, 2015, 04:42:36 AM

Dear Andy,

Thanks!

I have one more query, slightly different that subject topic,
Due to my Profession I may have to stay Two Years in South Korea, Do you have any experience or information about the treatment center in South Korea (Seoul)

Regards,
Dip

Title: Re: Chelation to start
Post by: Canadian_Family on May 29, 2015, 07:17:01 PM

Just adding my two cents.

Our daughter Little Miss A is 12 years old and 65lbs. She is taking 375mg of exjade everyday. Her ferritin is below 1000.

I think 600mg is a bit two high, how did you come up with 600mg dose. Did the doctor recommended it.

Title: Re: Chelation to start
Post by: Andy Battaglia on May 30, 2015, 12:32:37 AM

Dip,

I was given this link for S Korea treatment. https://www.snuh.org/english/ihc/ihc04/sub02/sub01/

Title: Re: Chelation to start
Post by: dip1973 on May 30, 2015, 11:15:16 AM

Dear Andy

Thanks for you information.

Dear Canadian Family

the above dose is suggested by doctor.
But currently I am giving slightly leass than 400mg.