Thalassemia Patients and Friends

Discussion Forums => Thalassemia Major => Topic started by: jatin on July 05, 2016, 02:32:27 PM

Title: I v desferal taken how long
Post by: jatin on July 05, 2016, 02:32:27 PM

Hi all I have query pls reply and share experiences.
One of my know thal major patient ferrtin is around 6500 from last 2 yrs.
T2 * mri of heart is 11.0 ms
T2 * mri of liver is severe around 1
T2* mri of pancreas is 3.3 severe.
Patients is on deferasirox 500 mg 4 tabs.
Weight is 40 kg ..
He has taken inj.desferal  for sat sun by pump for around 6 months .
Pls suggest what is max numbers of days I'v desferal can be given .thanks

Title: Re: I v desferal taken how long
Post by: Andy Battaglia on July 09, 2016, 02:12:51 AM

IV desferal is usually given for no more than two weeks at a time, unless the patient is in heart failure. In between IV sessions, pumping should continue at least 5 times per week. The patient's dose of deferasirox is too low. With those iron numbers, the patient should be on high dose of at least 40 mg/kg daily. For this patient, it should be 1600-2000 mg daily, split into two doses to maximize the benefit. It is critical that aggressive chelation be undertaken for at least two years.