Thalassemia Patients and Friends

Discussion Forums => Thalassemia Minor => Topic started by: dennis1106 on September 26, 2017, 06:14:48 PM

Title: Silent Alpha Thalassemia Dad with HbE Disease Mom
Post by: dennis1106 on September 26, 2017, 06:14:48 PM

I'm a silent Alpha Thalassemia carrier and my wife got HbE disease. is it possible for us to have a baby?
Will my baby have any major thalassemia disease or anaemia disease??

Title: Re: Silent Alpha Thalassemia Dad with HbE Disease Mom
Post by: Melissa A Tan on February 20, 2020, 02:50:57 PM

Hi! Any updates since this post? Does your child carry both traits?

Title: Re: Silent Alpha Thalassemia Dad with HbE Disease Mom
Post by: Andy Battaglia on February 28, 2020, 11:08:44 PM

I believe this was answered at a second post, but since HbE and alpha thal affect different genes, there is no danger of producing a child with a major condition.

Title: Re: Silent Alpha Thalassemia Dad with HbE Disease Mom
Post by: Melissa A Tan on March 01, 2020, 10:40:21 PM

Thanks Andy. I was curious since my daughter has Alpha II minor as well as HbE trait and has a whole hosts of issues. She is seen by neurology, psychiatry, haematology (going for first appointment this month) and cardiology. Her issues started at the onset of puberty. My son is Alpha II.

Title: Re: Silent Alpha Thalassemia Dad with HbE Disease Mom
Post by: Andy Battaglia on March 22, 2020, 10:00:50 PM

Both children should take folate (not folic acid) supplements. I continue to get reports that patients do better when L-methylfolate and sublingual vitamin B-12 are taken.

Title: Re: Silent Alpha Thalassemia Dad with HbE Disease Mom
Post by: Melissa A Tan on March 30, 2020, 09:02:58 AM

Both of my children are on sublingual methylcobalamin as well as l-methylfolate. My daughter has a mood disorder too which makes it even tougher.