ANDY SIR PLZ HELP

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Offline jatinder

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ANDY SIR PLZ HELP
« on: November 21, 2008, 05:59:29 AM »
DEAR ANDY,

i m taking ferriprox at the dose of 7 tabs(500mg each) per day.

and the problem is when i take the tabs the urine comes red colour.

so i m doubt that isnt this blood.

does the urine comes red when taking ferriprox.

plz help me

JATINDER KEWLANI
www.thalspoint.com

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Offline Andy Battaglia

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Re: ANDY SIR PLZ HELP
« Reply #1 on: November 21, 2008, 06:33:20 AM »
Iron being chelated causes red urine with desferal and to some extent with L1 also. This varies from patient to patient and is related to iron load and dose of the drug.

http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=2376085

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Reddish discoloration of urine due to excretion of the iron-deferiprone complex has been reported in Deferiprone (DFP, Ferriprox™, Kelfer™, L1, CP20) treated patients.

http://cat.inist.fr/?aModele=afficheN&cpsidt=14871185

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It increases urinary iron excretion, which mainly depends on the iron load of patients and the dose of the drug. It decreases serum ferritin levels and reduces the liver and heart iron content in the majority of chronically transfused iron loaded patients at doses >80 mg/kg/day. It is metabolised to a glucuronide conjugate and cleared through the urine in the metabolised and a non-metabolised form, usually of a 3 deferiprone: I iron complex, which gives the characteristic red colour urine.
Andy

All we are saying is give thals a chance.

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Offline Lena

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Re: ANDY SIR PLZ HELP
« Reply #2 on: November 21, 2008, 06:50:26 AM »
Do not worry, it does come red. I also take 7 ferriprox per day and it happens the same. It is good that it comes red. It shows you have iron to be chelated.The redder,in fact, the better and if you take vit c, it will help more.

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Offline Andy Battaglia

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Re: ANDY SIR PLZ HELP
« Reply #3 on: November 21, 2008, 07:08:56 AM »
Lena,

Because there have been no studies done with L1 and vitamin C, we have to rely on personal reports on how it has worked for people. How long have you used vitamin C with Ferriprox and how much do you take daily?
Andy

All we are saying is give thals a chance.

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Offline jatinder

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Re: ANDY SIR PLZ HELP
« Reply #4 on: November 21, 2008, 05:02:47 PM »
thanx andy and lena for help and getting me out from this doubt.

well well  is it necessary  to take vitamin c with ferriprox. :huh
i dont take that one.

thankx and rgrds :hugfriend :hugfriend
jatinder kewlani

JATINDER KEWLANI
www.thalspoint.com

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Offline Lena

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Re: ANDY SIR PLZ HELP
« Reply #5 on: November 21, 2008, 06:21:31 PM »
Hi Andy, hi jatinder

Glad to have helped.

Yes Andy I take vit C with Ferriprox from the start, which is 5 years ago when I started taking Ferriprox.I take 250 mg per day, preferably with the evening dosage and together with desferal too. It works out well with ferriprox too. Greek thals take vitamin C this way.

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Offline Smurfette

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Re: ANDY SIR PLZ HELP
« Reply #6 on: November 22, 2008, 04:40:34 AM »
Lena!

Who is your doctor in Greece? and do you go to the hospital in Athens?


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Offline Lena

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Re: ANDY SIR PLZ HELP
« Reply #7 on: November 22, 2008, 06:11:44 AM »
Hi Smurfette,

No, I do not go to any Athens hospital. I am transfused in the hospital of Corinth. But are you Greek?

 

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