Thal beta minor and Hemangiona

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Offline Ginni

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Thal beta minor and Hemangiona
« on: December 08, 2008, 09:36:19 PM »
Hi. I am 30 yrs old and a beta thal minor. offlate have been having pain in my abdomen quite often. I got an ultrasound done for my abdomen and couple of other blood and liver tests as well like CBC, ESR, SGPT, Biblurin etc. All the tests have come normal but there has been a a small 14mm most likely hemangiona in the right lobe of my liver. Could hemangiona be somehow related with Thal. Is it common in thals to develop such a blood clot? I would be meeting a gastro specialist in another couple of days to determine whether it actually is only a non significant hemangioma or is it a significant tumour. DOes anyone have any information about hemangiona? Thanks.... Ginni

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Offline Manal

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Re: Thal beta minor and Hemangiona
« Reply #1 on: December 09, 2008, 04:07:32 AM »
Actually i have no information about this issue but you can read this articel which will give you a clearer picture

http://www.medicinenet.com/hepatic_hemangioma/article.htm

Hope this helps

manal

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Offline Andy Battaglia

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Re: Thal beta minor and Hemangiona
« Reply #2 on: December 09, 2008, 04:32:26 AM »
There doesn't appear to be any connection between hepatic hemangioma and thalassemia. These are mostly associated with hormones or oral contraceptives. Abdominal pain is common but usually they are not treated unless they get fairly large. Mostly they are benign. If necessary, a CT scan or MRI may be done to further investigate it.
Andy

All we are saying is give thals a chance.

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Offline Dori

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Re: Thal beta minor and Hemangiona
« Reply #3 on: December 09, 2008, 11:22:04 AM »
Ok,

I can't have a look in an email now, since im at college.
There's a link with an other disorder. Someone must remind me of this.
That's Umair's task  :biggrin .  I won't be able to do that before wednesday.

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Offline nice friend

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Re: Thal beta minor and Hemangiona
« Reply #4 on: December 09, 2008, 03:50:58 PM »
http://www.uic.edu/depts/mcpt/curriculum/liver48_gc_lecture.html
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Pigment stones:

They are generally black or brown stones.

Black stones measure less than 1 cm and contain calcium bilirubinate, calcium salts and mucin. It is found in old and undernourished persons, sickle cell anemia, cirrhosis and thalassemia. It is related to high concentration of unconjugated bilirubin in the bile, which becomes insoluble in bile and precipitates as calcium bilirubinate, around a nidus of mucin.


Hemangioma:

It is the most common benign tumor of the liver, found in 7% of autopsies. They are usually small,
asymptomatic, solitary.

Cysts:

Liver cysts may be solitary or multiple, lined by cuboidal or columnar epithelium, often associated with
adult polycystic kidney disease.

The cysts may be microscopic, surrounded by fibrous tissue ("bile duct microhamartomas, Von Meyenburg complexes").

Congenital hepatic fibrosis is a recessive hereditary disorder with large portal tracts containing fibrous tissue
and numerous bile ducts, which communicate with the biliary tree; mainly seen in children and adolescents.
The fibrosis is sharply demarcated from the liver parenchyma. Patients may develop portal hypertension and bleeding from esophageal varices.


http://radiographics.rsnajnls.org/cgi/content/full/20/2/367
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Hepatocellular Adenoma
Hepatocellular adenoma is a rare benign liver tumor of uncertain origin. Since the introduction of oral contraceptives in 1960, its occurrence has increased dramatically, with an estimated incidence of four cases per year per 100,000 patients using long-term oral contraceptives (19–22). [bgcolor=#f5ff00]It is also seen in patients with glycogen storage disease, diabetes mellitus, or iron overload secondary to ß-thalassemia and in males using anabolic androgenic steroids (19–21). At histologic analysis, hepatocellular adenoma is characterized by cords of well-differentiated hepatocytes that can produce bile; however, there are no bile ductules present to enable biliary excretion[/bgcolor]. The hepatocytes are commonly rich in fat and glycogen. The tumor architecture lacks portal vein tracts and terminal hepatic veins, thus helping differentiate it from normal liver tissue or adenomatous hyperplasia. Hepatocellular adenoma manifests as a solitary lesion in 80% of cases and multiple lesions in 20% and is associated with an increased risk of malignant transformation. It may be clinically silent and may be incidentally discovered at laparotomy for an unrelated problem or appear as an asymptomatic RUQ mass at imaging. Hepatic adenomas may rupture and manifest as limited bleeding causing RUQ pain suggestive of acute cholecystitis. On occasion, the initial bleeding may be severe enough to produce hemorrhagic shock. Rapid hemostasis is essential for survival (22).

i dont know that i m poitning towards right probleme or wrong but  i found this , soo please if anybuddy know abt it please explain it ... and also let me know that i found riight thing or wrong ... please read both articles completely..

Best Regards
Umair
Sometimes , God breaks our spirit to save our soul.
Sometimes , He breaks our heart to make us whole.
Sometimes , He sends us pain so we can be stronger.
Sometimes , He sends us failure so we can be humble.
Sometimes , He sends us illness so we can take better care of our selves.
Sometimes , He takes everything away from us so we can learn the value of everything we have.

===========
Umair

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Offline Dori

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Re: Thal beta minor and Hemangiona
« Reply #5 on: December 09, 2008, 11:32:14 PM »
I am sorry, I didnt read very good this morning.
I know there is link between iron overload and  porphyria
Me is told that The American Porphyria Foundation has a great website.

 

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