Test for early daignoss of cardiac problems

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Offline jatin

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Test for early daignoss of cardiac problems
« on: August 22, 2018, 12:24:42 PM »
Hello all pls suggest test for early daignoss of cardiac problem in Thalassemia major with severe iron overload.
As 2 D echo can't help much .
Our cardialogist are not trained for cardaic problem in thalassemia major .pls suggest what's are test should be done if t 2 * MRI is less than 8 ms .
Ferritin is more than 2500


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Offline Andy Battaglia

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Re: Test for early daignoss of cardiac problems
« Reply #1 on: August 25, 2018, 07:14:11 PM »
Jatin, in addition to the MUGA scan we discussed on Facebook, there is tissue Doppler imaging (TDI).

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4900296/
Quote
Cardiac complications are among the most serious complications in Beta Thalassemia Major Patients. Our aim was to evaluate the value of tissue Doppler imaging (TDI) for early detection of myocardial dysfunction in pediatric and adolescent patients with B-TM before development of overt heart failure or cardiomyopathy...
Conclusion
Clinically asymptomatic thalassemic children and adolescents who had normal global functions by conventional echo-Doppler were found to have abnormal left ventricular and right ventricular dysfunctions detected by TDI. TDI is superior to Echo-Doppler in detection of early myocardial damage in asymptomatic thalassaemic patients.
Andy

All we are saying is give thals a chance.

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Offline jatin

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Re: Test for early daignoss of cardiac problems
« Reply #2 on: August 26, 2018, 06:34:48 AM »
Thanks Andy sir for you prompt reply.
I am confused between this test which should be done or all test should be done .
1) Tissue Doppler
2) Muga Scan
3 CMri.
Which one is best .
Thanks a lot

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Offline Andy Battaglia

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Re: Test for early daignoss of cardiac problems
« Reply #3 on: September 01, 2018, 04:59:01 PM »
I believe the tissue Doppler will give you the information you are looking for.
Andy

All we are saying is give thals a chance.

 

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