• Welcome, Guest. Please login or register.
    May 13, 2021, 03:14:23 PM

  • Login with username, password and session length

Sajid's dove

Tell everyone they can now find this site by typing this into their browser:


Click to visit us on Facebook

If you have any problems registering or signing in, please send an email to: andythalpal@yahoo.com
Please do not send questions about thalassemia to this address.


Thalassemia Patients and Friends and thalpal thalpal.com © A. Battaglia 2021

55477 Posts in 5941 Topics by 6282 Members
Latest Member: Shane20

This is Thalassemia Patients and Friends,
dedicated to its founder,
Lisa Cammilleri.
« previous next »
Pages: 1 Go Down Print
Author Topic: CRISPR Therapeutics Plans to Treat First Patients for Beta Thalassemia in Europe  (Read 3249 times)
New Member
Offline Offline

Posts: 19

« on: April 16, 2018, 09:11:41 PM »

CRISPR Therapeutics Plans to Treat First Patients for Beta Thalassemia in Europe


In this trial, researchers will harvest stem cells from the patients and, using CRISPR gene-editing tools, repair the cells so they have increased levels of fetal hemoglobin. Once completed, they will be infused back into the patients’ bodies via stem cell transplant. If all goes according to plan, the cells will generate a healthy supply of hemoglobin.

It will be the first human disease treated using CRISPR in Europe. China has several ongoing trials for various diseases using CRISPR. Salveen Richter, an analyst with Goldman Sachs, told the Telegraph, “As of the end of February 2018 there were nine registered clinical studies testing CRISPR-edited cells to treat various cancers and HIV infection in China.” In the U.S., there is only one. That is at the University of Pennsylvania for melanoma, sarcoma, and multiple myeloma.

“Certainly, 2018 promises to be the big year for clinical trials using CRISPR based genome editing,” Helen O’Neill, a geneticist from University College London (UCL), told the Telegraph. “Results presented by [CRISPR Therapeutics] at a hematology meeting showed that the method dramatically increased fetal hemoglobin in beta thalassemia patients’ cells. The therapy successfully edited over 90 percent of blood stem cells removed form patients, which were retransfused.”
Pages: 1 Go Up Print 
« previous next »
Jump to:  

Powered by MySQL Powered by PHP Powered by SMF 1.1.21 | SMF © 2015, Simple Machines Valid XHTML 1.0! Valid CSS!