Help with test results please

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Help with test results please
« on: June 07, 2022, 08:23:08 PM »
Hi,

I have just joined to try and get some help with my blood test results, I am a 43 year old male (from the UK); I have had lots of odd issues over the last 10 years but GP recently did some blood tests after constantly feeling fatigued.

The blood test results are from 6 weeks ago:

Haemoglobin A2:       2.7%
Haemoglobin F:         0.9%
Haemoglobin A:   84.5% ?
Haemoglobin estimation:   143g/L   (130 – 180)
RBC:                    4.91 (4.50 – 6.00)
Haematocrit:         0.399 (0.400 – 0.520)
MCV:            84 fL (80 – 98)
MCH:            29.1 pg (27.0 – 33.0)
MCHC:            349 g/L (320 – 365)
Platelet count:         139 (150 – 400) ABNORMAL
Percentage reticulocytes:   1.70% (0.50 – 1.50) ABNORMAL
Reticulocyte count:      74 (20 – 80)
RETICULOCYTE HB:      33.7 pg (28.0 – 30.8) ABNORMAL
Immature Platelet Fraction:   16.1% (0.0 – 6.0) ABNORMAL

I am not worried about the blood tests as I know that the Hb, MCV etc are normal; I just wanted to ask about the Haemoglobin A - 84.5% - the GP I spoke to was a junior doctor, so wasn't able to help. As normal Haemoglobin A is 95 - 98%, should I follow this up in that I could be a carrier. Any advice would be greatly appreciated and apologies in advance as I am not familiar with Haemoglobinopathies.
« Last Edit: June 07, 2022, 08:34:27 PM by andib »

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Offline Andy Battaglia

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Re: Help with test results please
« Reply #1 on: September 03, 2022, 07:59:07 PM »
I would get tested again, since your latest results don't match prior tests and also do not include other types of hemoglobin that would cause a lower HbA if present.
Andy

All we are saying is give thals a chance.

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Offline TonyF

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Re: Help with test results please
« Reply #2 on: December 07, 2022, 11:50:56 PM »
Interesting! I'd never heard of different types of HB!

https://www.biron.com/en/glossary/hb-a-hb-a2-hb-a1/

Andy - is there any use in getting the different types measured? I suspect a regular doc wont see the value in checking it.



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Offline Andy Battaglia

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Re: Help with test results please
« Reply #3 on: January 07, 2023, 08:17:59 PM »
When a hemoglobin electrophoresis test is done, it gives the breakdowns of the types of Hemoglobin one has. A non-thal will have mostly HbA and small amounts of HbA2 and HbF. HbA2 is normally raised in thal minors and is used to diagnose the condition.
Andy

All we are saying is give thals a chance.

 

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